Numerous theories of ageing have been proposed, and many have been tested experimentally, particularly
using nematode models such as Caenorhabditis elegans. By combining those theories of ageing that remain
plausible with recent findings from studies of C. elegans life span mutants, an integrated theory of ageing
has been devised. This is formed from 3 interconnected elements: the evolutionary theory of ageing, the
oxidative damage theory of ageing, and a nonadaptive programmed ageing theory. This tripartite theory of
ageing gives rise to a number of predictions that may be tested experimentally.
