This article argues that the notion of cultural biography presents a key to understanding the social and cultural practices that created archaeological records of domestic architecture, as it brings the close and dynamic relationships between a house and its inhabitants to the fore. To do so it presents a case study of the construction, habitation and abandonment cycles of late prehistoric farmsteads in the southern Netherlands. After discussing typical biographies of farmhouses and the way these are affected by a transformation from a ‘wandering’ to a stable settlement pattern, the perspective is broadened through a comparison with burial practices. These witness a roughly contemporaneous shift from monumental and communal to short-lived and dispersed cemeteries. Finally, it is suggested that we view these contrasting patterns in terms of a transformation of the perception of farmsteads as places in the landscape and land tenure practices.