The political involvement of adolescents is characterized by a substantial socioeconomic gradient already at a young age with enduring effects into adulthood. This study investigates whether high parental income creates an enhancing environment that increases the influence of genetic dispositions on political interest using the German TwinLife study (2014–2020, age 10–29, n = 6,174, 54% female, 19% migration background). While 30–40% of the total variance in political interest of twin adolescents (age 10–18) can be attributed to genetic influences, a gene–environment interaction model shows that this share is much lower among poor compared to rich families. Family fixed-effects models among early adults further show no significant effect of income differences on political interest after controlling for family background and genetic influences. This study suggests that the income gap in political participation cannot be fully understood without accounting for life cycle processes and genetic background.