The purpose of this note is to show that the Betti realization of motives is compatible with Grothendieck's six operations and the nearby cycles functors, which in the motivic world, were previously studied by the author. We first review the construction of the Betti realization. Then, we establish some general criteria which, applied to the Betti realization, give the compatibilities we seek except for the one concerning the nearby cycles functors. The latter will be treated in a separate section.