The eruption of protests within consolidated authoritarian regimes is an infrequent event seen by many scholars as resulting from the separatist intentions of a regional elite enabled by autonomy. In this article, by analysing the July 2022 protest events in Karakalpakstan we challenge this assumed link and instead propose that the emergence of large-scale protests formed as a grassroots reaction to the symbolic loss of the region’s nominal autonomy, state repression, and the detention of popular activists. Based on semi-structured interviews in Karakalpakstan, research findings reveal a moderate and mostly non-separatist approach to the Karakalpak question and a high interconnection with Uzbekistan. The existence of an authoritarian regime in Uzbekistan and its repression mechanisms can provide a straightforward explanation of non-resistant character of Karakalpak population. However, the research showed the strong notion of Karakalpak identity, not being transformed into political demands if Uzbekistan does not harm it.