The definitions of disability adopted in the UN Convention on the Rights of Persons with Disabilities (CRPD) necessitate an important change in the way disability is assessed and introduce a new idea of justice in relation to persons with disabilities. The article starts by reviewing the various ‘models of disability’ prevailing in the past and the respective ideas of justice underlying them. The charity model, for instance, was rooted in ideas of divine justice and human beneficence, where care for the disabled led in practice to their being segregated from the rest of society, while the medical model saw justice in terms of treatments or compensations for individual pathologies rather than of positive enablement for active living. The CRPD overturns these models and the related conceptions of justice by emphasising society's obligations towards persons with disabilities and, above all, their human right to full inclusion and participation in society. The key concepts are empowerment and capability. In Italy these concepts and this new conception of justice have started to be applied by the Osservatorio nazionale sulla condizione delle persone con disabilità, the body created to monitor the effective application of the CRPD in Italy, and they are included in the two-year action programme on disability, approved by the Italian government in October 2013.