Based on current commercial aquaculture production practices, the production cycle for Atlantic salmon (Salmo salar) extends over a 36-month period during which time the fish are first exposed to intensive freshwater rearing conditions followed by transportation to marine netpen sites for ongrowing. It is predictable that, because of the duration of the production cycle and the variety of water conditions, deleterious environmental conditions have many opportunities to affect salmon health directly and indirectly. Furthermore, diseases which are iatrogenic arise from current methods used to prevent or treat infectious diseases. Specific, more frequently encountered examples are explored, with reference to the possible roles which these diseases may have in favouring the onset of infectious diseases.