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1 results

  • Chapter 26 - Post-herpetic Neuralgia (PHN)

  • from Part VI - Misc
  • Edited by Omar Viswanath, Creighton University, Omaha, Ivan Urits, Southcoast Brain & Spine Center, Wareham
  • Book:
    Cambridge Handbook of Pain Medicine
    Published online:
    01 December 2023
    Print publication:
    14 December 2023, pp 213-219

  • Summary

    Post-herpetic neuralgia (PHN) is a common, painful reaction following herpes zoster (HZ) infection. There have been one million cases of HZ per year, with 20% resulting in PHN, which is the prevalent condition that significantly reduces the quality of life in affected individuals. There is increased nociception in dermatomal region following typical HZ rash. The strongest risk factor is increasing age, and the FDA recommends all people age >50 to get vaccinated as a prevention. First-line treatments include topical capsaicin, lidocaine, and pharmacological management with TCAs and Calcium channel a2d ligands. Myriad of other treatment options are available, many with conflicting evidence.