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A 31-year-old nulligravida with a body mass index (BMI) of 42 kg/m2 is referred by her primary care provider to your high-risk obstetrics clinic for preconception counseling. Prior to the consultation, you highlight to your obstetric trainee that motivational interviewing with nonstigmatizing terminology avoids negative influences on mood and self-esteem, promoting patient uptake of weight management strategies and a healthy lifestyle.
A 28-year-old nulligravida with Marfan syndrome is referred to your tertiary center’s high-risk obstetric unit for preconceptional counseling. She has no other medical issues.
During your call duty, a healthy 32-year-old primigravida at 22+3 weeks’ gestation, confirmed by first-trimester sonography, presents to the obstetrics emergency assessment unit of your hospital center with new-onset, asymptomatic port-wine-colored urine with chills and an oral temperature of 39.1°C at home; she also notes a two-day history of headache, now accompanied by visual changes. Your obstetric trainee informs you that clinical history is not suggestive of an infectious etiology, although comprehensive investigations are pending. She has no obstetric complaints, and fetal viability was ascertained upon presentation. Routine prenatal laboratory investigations, aneuploidy screening, and fetal morphology survey were unremarkable. The laboratory urgently notifies you that the platelet concentration is 12 × 109/L, confirmed on manual count; other requested laboratory tests are in progress.
During your overnight call duty, a 37-year-old G2P1 with a spontaneous pregnancy presents to the obstetrics emergency assessment unit of your tertiary center at 32+3 weeks’ gestation with pruritis preventing her from sleep. She has no obstetric complaints; cardiotocography initiated upon the patient’s presentation shows a normal fetal heart tracing and uterine quiescence.
A 30-year-old nulligravida with epilepsy is referred by her primary care provider to your hospital center’s high-risk obstetrics unit for preconception counseling.
A 28-year-old nulligravida with known factor V Leiden mutation is referred by her primary care provider to your hospital center’s high-risk obstetrics unit for preconception counseling.
A 37-year-old G1P1 with a three-year history of type 2 diabetes mellitus (T2DM) is referred by her primary care provider to your high-risk obstetrics clinic for preconception counseling. Six years ago, she delivered her son at another hospital center.
A 29-year-old primigravida is referred by her primary care provider to your tertiary center’s high-risk obstetrics unit for preconception counseling for known Graves’ disease.
A 25-year-old G2P1 presents for prenatal care at 8+2 weeks’ gestation by menstrual dates with complaints of nausea and vomiting for the past two weeks. Your clinical nurse reassures you the patient is not in acute distress and converses well. There is no history of vaginal bleeding.
A 28-year-old nulligravida is referred by her primary care provider to your high-risk obstetrics clinic for preconception counseling for known systemic lupus erythematosus (SLE).
A 43-year-old G1P1 is referred by her primary care provider to your hospital center’s high-risk obstetrics unit for preconception counseling for advanced maternal age (AMA). She started folic-containing prenatal vitamins and has recently discontinued five-year use of a copper intrauterine contraceptive device. They wish to attempt spontaneous conception prior to considering fertility evaluation.
You are seeing a healthy 28-year-old primigravida for her second prenatal visit. She is currently at 14 weeks’ gestation and works at an accounting firm. All routine prenatal laboratory investigations as well as first-trimester fetal anatomy and aneuploidy screenings are unremarkable. Incidentally, she tells you her friend is away for the summer, leaving her to care for two cats.
During your on-call duty, a 34-year-old primigravida at 23 weeks’ gestation with no systemic condition presents to the obstetric emergency assessment unit with a one-day history of a headache.
A 32-year-old healthy primigravida at 13+2 weeks’ gestation is referred by her primary care provider for urgent consultation at your high-risk obstetrics clinic. Four days ago, at the first prenatal visit, she reported feeling ‘unwell’ for a few days upon returning from an urgent family trip to a country with a Zika virus outbreak. By the time of initial prenatal visit, the patient had recovered from her illness; examination was unremarkable. First-trimester dating sonography was concordant with menstrual dates, and fetal morphology appeared normal, with a low risk of aneuploidy. Results of routine prenatal investigations are normal. The patient does not work, has healthy social habits, and takes only prenatal vitamins. She has not experienced nausea, vomiting, abdominal cramps, or vaginal bleeding. In very early gestation, she required emergent medical treatment for an allergic reaction after inadvertent exposure to a neighbor’s cat.
A 30-year-old G6P2A4L1 is referred by her primary care provider to your high-risk obstetrics clinic for preconception counseling after a pregnancy loss at 21+4 weeks’ gestation last year, shortly after incidental transvaginal cervical shortening was noted at second-trimester fetal morphology survey. After an uncomplicated first pregnancy and term delivery, she experienced four consecutive first-trimester losses for which comprehensive investigations were unremarkable.
A 26-year-old G2P1 with Crohn’s disease (CD) is referred by her primary care provider to your high-risk obstetrics unit for transfer of care at 10 weeks’ gestation by dating sonography. Routine prenatal investigations are unremarkable. She has no obstetric complaints.
A 32-year-old nulligravida with a history of mitral valve replacement is referred by her cardiologist to your high-risk obstetrics clinic for preconception consultation.
A 30-year-old nulligravida with ulcerative colitis (UC) is referred by her primary care provider to your hospital center’s high-risk obstetrics unit for preconceptional counseling.
Preconception counseling is far beyond providing information about pregnancy to women prior to conception. It is an ultimate period for risk assessment, health promotion and medical/psychosocial interventions. Low pre-pregnancy weight increases risks for preterm birth and low birth weight both associated with significant neonatal morbidity. The assessment of the woman's vaccination history is strongly recommended before beginning the treatment of infertility. Identified risk factors that require referral to genetic counseling include developmental delay, congenital anomalies or any genetic family disorders, chromosomal anomalies or known genetic conditions in at least one member of a couple. For the majority of chronic diseases, optimal control prior to conception is associated with favorable maternal and neonatal outcomes. Men should be targeted because their lifestyle and general health affect semen quality and the health of their offspring, and influence women's compliance with recommendations.
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