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Chapter 66 - Toxoplasmosis in Pregnancy

from Section 11 - Infectious Conditions in Pregnancy

Published online by Cambridge University Press:  23 February 2023

By
Amira El-Messidi
Edited by
Amira El-Messidi  and
Alan D. Cameron
Amira El-Messidi
Affiliation:
McGill University, Montréal
Alan D. Cameron
Affiliation:
University of Glasgow
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Summary

You are seeing a healthy 28-year-old primigravida for her second prenatal visit. She is currently at 14 weeks’ gestation and works at an accounting firm. All routine prenatal laboratory investigations as well as first-trimester fetal anatomy and aneuploidy screenings are unremarkable. Incidentally, she tells you her friend is away for the summer, leaving her to care for two cats.

Keywords

Toxoplasmosis, T. gondii, pregnancyPrevention, lifestyle interventionsMaternal serology, diagnosis, avidity testing,Congenital toxoplasmosis, fetal sonographyTetrad, neonatal toxoplasmosisFetal prophylaxisPerinatal risks, complications, fetal morbidity, adverse outcomeAntepartum management, counselingPreconception counselingTreatment, spiramycin, pyrimethamine, folinic acid, sulfadiazineObstetric delivery
Type
Chapter
Information
OSCEs in Obstetrics and Maternal-Fetal Medicine
An Evidence-Based Approach
 , pp. 843 - 850
Publisher: Cambridge University Press
Print publication year: 2023

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References

Suggested Readings

Berghella, V. Maternal-Fetal Evidence-Based Guidelines. Boca Raton, FL: CRC Press; 2017.Google Scholar
Centers for Disease Control and Prevention. Available at www.cdc.gov/parasites/toxoplasmosis/. Accessed July 26, 2020.Google Scholar
Montoya, JG, Liesenfeld, O. Toxoplasmosis. Lancet 2004;36:1965–1976.CrossRefGoogle Scholar
Montoya, JG, Remington, JS. Management of Toxoplasma gondii infection during pregnancy. Clinical Infectious Diseases 2008;47(4):554–566.CrossRefGoogle ScholarPubMed
Paquet, C, Yudin, MH. No. 285 – toxoplasmosis in pregnancy: prevention, screening, and treatment. J Obstet Gynaecol Can. 2018;40(8):e687–e693.Google Scholar
Petersen, E. Toxoplasmosis. Semin Fetal Neonatal Med. 2007;12(3):214–223.Google Scholar
Saso, A, Bamford, A, Grewal, K, et al. Fifteen-minute consultation: management of the infant born to a mother with toxoplasmosis in pregnancy. Arch Dis Child Educ Pract Ed 2020.Google Scholar
Villard, O, Cimon, B, L’Ollivier, C, et al. Serological diagnosis of Toxoplasma gondii infection: recommendations from the French National Reference Center for Toxoplasmosis. Diagn Microbiol Infect Dis. 2016;84(1):22–33.Google Scholar

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