The generating function methods have been applied successfully to generalized Hamiltonian systems with constant or invertible Poisson-structure matrices. In this paper, we extend these results and present the generating function methods preserving the Poisson structures for generalized Hamiltonian systems with general variable Poisson-structure matrices. In particular, some obtained Poisson schemes are applied efficiently to some dynamical systems which can be written into generalized Hamiltonian systems (such as generalized Lotka-Volterra systems, Robbins equations and so on).
