Field studies were conducted from 2005 to 2009 in Idaho and Oregon to 1) evaluate the competitive effect of volunteer potato on sugar beet yield (volunteer potato competition experiment), and 2) determine the optimum timing of volunteer potato removal from glyphosate-tolerant sugar beet fields using glyphosate (volunteer potato removal timing experiment). The volunteer potato competition experiment consisted of eight potato densities, including the untreated check: 0, 6,741, 10,092, 13,455, 16,818, 20,184, 26,910, and 40,365 tubers ha−1. The volunteer potato removal experiment consisted of 10 removal timings (including the untreated check) ranging from the 10-cm rosette stage to mid-tuber bulking. There was a linear decrease in sugar beet root and sucrose yield as volunteer potato density increased (P < 0.001) such that with every volunteer potato tuber per square meter, sugar beet root yield decreased by 15% and sucrose yield decreased by 14%. At the highest volunteer potato density (40,365 tubers ha−1), sugar beet root yield was 29,600 kg ha−1 (compared to 73,600 kg ha−1 for the untreated), representing a 60% reduction in sugar beet root yield. In the removal timing study, a one-time application of glyphosate at the 10-cm rosette, hooking, and tuber initiation stages provided 74% to 98% reduction in volunteer potato tuber biomass. Delaying volunteer potato removal beyond the tuber initiation stage reduced sugar beet root and sucrose yield (12% to 20%), resulting in an economic loss of $104 to $161 per hectare. The best potato removal timing that optimizes the trade-off between improved control and potential for sugar beet yield reductions is before or at the tuber initiation stage.