MDLs rely, for legitimacy, on the notion that the individual litigant calls the shots. That fact justifies a system that affords MDL litigants few, if any, safeguards, even while furnishing class members in class actions elaborate procedural protections. In this Chapter, we zero in on litigant autonomy in MDLs. We explain why autonomy matters, dissect its components, and evaluate how much autonomy MDL litigants seem to have in practice. We then turn to a necessary component of that autonomy: information. We review data from a recent survey indicating litigants felt confused and uninformed regarding their suits. In light of that evidence, we assess what transferee courts are doing to keep litigants up-to-date and well informed. We then furnish the results of our own empirical analysis of court-run MDL websites, which are often extolled, including by judges, as a key venue for client-court communication. Unfortunately, our analysis reveals deep and pervasive deficits with respect to usability and relevance. If this is where case-related communication is supposed to be happening, then litigant confusion is unsurprising. We close with recommendations for courts seeking to harness simple technology to promote better communication. Improved MDL websites aren’t a panacea. But they might promote the autonomy interests of litigants—and light a path for future reform.