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Section 11 - Diseases of Body Systems

Published online by Cambridge University Press:  18 June 2025

Edited by
David Mabey ,
Martin W. Weber ,
Moffat Nyirenda ,
Dorothy Yeboah-Manu ,
Jackson Orem ,
Laura Benjamin ,
Michael Marks  and
Nicholas A. Feasey
David Mabey
Affiliation:
London School of Hygiene and Tropical Medicine
Martin W. Weber
Affiliation:
World Health Organization
Moffat Nyirenda
Affiliation:
London School of Hygiene and Tropical Medicine
Dorothy Yeboah-Manu
Affiliation:
Noguchi Memorial Institute for Medical Research, University of Ghana
Jackson Orem
Affiliation:
Uganda Cancer Institute, Kampala
Laura Benjamin
Affiliation:
University College London
Michael Marks
Affiliation:
London School of Hygiene and Tropical Medicine
Nicholas A. Feasey
Affiliation:
Liverpool School of Tropical Medicine
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Principles of Medicine in Africa , pp. 705 - 978
Publisher: Cambridge University Press
Print publication year: 2025

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References

References

Andy, J J, Ogunowo, P O et al. (1998). Helminth associated eosinophilia and tropical endomyocardial fibrosis (EMF) in Nigeria. Acta Trop 69: 127–140.10.1016/S0001-706X(97)00125-3CrossRefGoogle ScholarPubMed
Arguedas, A & Mohs, E (1992). Prevention of rheumatic fever in Costa Rica. J Pediatr 121(4): 569–572.CrossRefGoogle ScholarPubMed
Barillari, A, Barillari, G et al. (2011). Extended compression ultrasound performed by emergency physicians: a modified compression ultrasound examination to detect superficial and deep lower limb thromboses in the emergency department. J Med Ultrasound 19(103e108).10.1016/j.jmu.2011.08.005CrossRefGoogle Scholar
Bukhman, G, Ziegler, J et al. (2008). Endomyocardial fibrosis: still a mystery after 60 years. PLoS Negl Trop Dis 2(2): e97.10.1371/journal.pntd.0000097CrossRefGoogle Scholar
Freers, J, Masembe, V et al. (2000). Peritoneal fibrosis and muscle fibrosis are part of the endomyocardial fibrosis (EMF) syndrome. Lancet 355: 1994.CrossRefGoogle Scholar
Freers, J, Mayanja-Kizza, H et al. (1996). Endomyocardial fibrosis: why is there striking ascites with little or no peripheral oedema? Lancet 347: 197.10.1016/S0140-6736(96)90383-9CrossRefGoogle ScholarPubMed
Gewitz, MH, Baltimore, RS et al. (2015). Revision of the Jones Criteria for the diagnosis of acute rheumatic fever in the era of Doppler echocardiography: a scientific statement from the American Heart Association. Circulation 131(20): 1806–1818.CrossRefGoogle Scholar
Hahn, D, Thomson, PD et al. (1998). A review of Takayasu’s arteritis in children in Gauteng, South Africa. Pediatr Nephrol 12(8): 668–675.10.1007/s004670050526CrossRefGoogle ScholarPubMed
Johnson-Coyle, L, Jensen, L et al. (2012). Peripartum cardiomyopathy: review and practice guidelines. Am J Crit Care 21(2): 89–98.10.4037/ajcc2012163CrossRefGoogle ScholarPubMed
Kingue, S, Kamdaju, R et al. (1999). Pronostic de la cardiomyopathic dilatée chez le noir africain de l’insuffisance cardiaque. Cardiol Trop 25: 49–53.Google Scholar
Kline, JA, Courtney, DM et al. (2008). Prospective multicenter evaluation of the pulmonary embolism rule-out criteria. J Thromb Haemost 6(5): 772–780.10.1111/j.1538-7836.2008.02944.xCrossRefGoogle ScholarPubMed
Marijon, E, Ou, P et al. (2007). Prevalence of rheumatic heart disease detected by echocardiographic screening. N Engl J Med 357(5): 470–476.10.1056/NEJMoa065085CrossRefGoogle ScholarPubMed
Mayanja-Kizza, H, Gerwing, E et al. (2000). Tropical endomyocardial fibrosis in Uganda: the tribal and geographic distribution, and the association with eosinophilia. Trop Cardiol 103: 45–48.Google Scholar
Mayosi, BM (2007). Contemporary trends in the epidemiology and management of cardiomyopathy and pericarditis in sub-Saharan Africa. Heart 93(10): 1176–83. doi: 10.1136/hrt.2007.127746.CrossRefGoogle ScholarPubMed
Mayosi, BM and Scott, Millar RN (2000). Permanent cardiac pacing in South Africa. East Afr Med J 77(6): 339.Google ScholarPubMed
Messias-Reason, IJ, Hayashi, SY et al. (2002). Complement activation in infective endocarditis: correlation with extracardiac manifestations and prognosis. Clin Exp Immunol 127(2): 310–315.CrossRefGoogle ScholarPubMed
Mocumbi, AO, Ferreira, MB et al. (2008). A population study of endomyocardial fibrosis in a rural area of Mozambique. N Engl J Med 359(1): 43–49.10.1056/NEJMoa0708629CrossRefGoogle Scholar
Opio, M O & Kellett, J (2017a). How well are pulses measured? practice-based evidence from an observational study of acutely ill medical patients during hospital admission. Am J Med 130(7): 863 e813–863 e816.10.1016/j.amjmed.2017.01.033CrossRefGoogle ScholarPubMed
Opio, M O & Kellett, J (2017b). An observational study of the quality of ECGs recorded by inexperienced staff in a resource-poor African hospital using a reusable ECG belt linked to an internet ECG device. Eur J Intern Med 42: e17–e18.10.1016/j.ejim.2017.04.004CrossRefGoogle Scholar
Rees, DC, Williams, TN et al. (2010). Sickle cell disease. Lancet 376: 2018–2031.10.1016/S0140-6736(10)61029-XCrossRefGoogle ScholarPubMed
Regitz-Zagrosek, V, Roos-Hesselink, J W et al. (2018). 2018 ESC Guidelines for the management of cardiovascular diseases during pregnancy. Eur Heart J 39(34): 3165–3241.10.1093/eurheartj/ehy340CrossRefGoogle ScholarPubMed
Rimbi, M, Dunsmuir, D et al. (2019). Respiratory rates observed over 15 and 30 s compared with rates measured over 60 s: practice-based evidence from an observational study of acutely ill adult medical patients during hospital admission. QJM 112(7): 513–517.10.1093/qjmed/hcz065CrossRefGoogle ScholarPubMed
Rutakingirwa, M, Ziegler, JL et al. (1999). Poverty and eosinophilia are risk factors for endomyocardial fibrosis (EMF) in Uganda. Trop Med Int Health 4: 229–235.CrossRefGoogle ScholarPubMed
Stewart, S, Wilkinson, D et al. (2008). Predominance of heart failure in the Heart of Soweto Study cohort: emerging challenges for urban African communities. Circulation 118(23): 2360–2367.CrossRefGoogle ScholarPubMed
Wells, PS, Anderson, DR et al. (2003). Evaluation of D-dimer in the diagnosis of suspected deep-vein thrombosis. N Engl J Med 349(13): 1227–1235.CrossRefGoogle ScholarPubMed
White, RH & Keenan, CR (2009). Effects of race and ethnicity on the incidence of venous thromboembolism. Thromb Res 123 Suppl. 4: S11–17.10.1016/S0049-3848(09)70136-7CrossRefGoogle ScholarPubMed
Wragg, A & Strang, J I (2000). Tuberculous pericarditis and HIV infection. Heart 84(2): 127–128.CrossRefGoogle ScholarPubMed
Wyber, R, Johnson, T et al. (2018). Tools for Implementing Rheumatic Heart Disease Control Progammes (TIPs) Handbook. 2nd ed. Geneva: RHD Action.Google Scholar
Zuhlke, L, Karthikeyan, G et al. (2016). Clinical outcomes in 3343 children and adults with rheumatic heart disease from 14 low- and middle-income countries: two-year follow-up of the Global Rheumatic Heart Disease Registry (the REMEDY Study). Circulation 134(19): 1456–1466.10.1161/CIRCULATIONAHA.116.024769CrossRefGoogle ScholarPubMed

References

Ashraf, N., Kubat, R. C., Poplin, V. et al. 2020. Re-drawing the maps for endemic mycoses. Mycopathologia, 185, 843–865.10.1007/s11046-020-00431-2CrossRefGoogle ScholarPubMed
Aston, S. J. & Rylance, J. 2016. Community-acquired pneumonia in sub-Saharan Africa. Semin Respir Crit Care Med, 37, 855–867.Google ScholarPubMed
Bruce, N., Dherani, M., Liu, R. et al. 2015. Does household use of biomass fuel cause lung cancer? A systematic review and evaluation of the evidence for the GBD 2010 study. Thorax, 70, 433–41.CrossRefGoogle ScholarPubMed
Corbett, E. L., Churchyard, G. J. et al. 2000. HIV infection and silicosis: the impact of two potent risk factors on the incidence of mycobacterial disease in South African miners. AIDS, 14, 2759–2768.10.1097/00002030-200012010-00016CrossRefGoogle ScholarPubMed
Cribbs, S. K., Crothers, K. & Morris, A. 2020. Pathogenesis of HIV-related lung disease: Immunity, infection, and inflammation. Physiol Rev, 100, 603–632.CrossRefGoogle ScholarPubMed
Crothers, K., Huang, L., Goulet, J. L. et al. 2011. HIV infection and risk for incident pulmonary diseases in the combination antiretroviral therapy era. Am J Respir Crit Care Med, 183, 388–95.10.1164/rccm.201006-0836OCCrossRefGoogle ScholarPubMed
Distefano, G., Fanzone, L., Palermo, M. et al. 2020. HRCT patterns of drug-induced interstitial lung diseases: a review. Diagnostics (Basel), 10, 244.10.3390/diagnostics10040244CrossRefGoogle ScholarPubMed
Fitzmaurice, C., Abate, D., Abbasi, N. et al. 2019. Global, regional, and national cancer incidence, mortality, years of life lost, years lived with disability, and disability-adjusted life-years for 29 cancer groups, 1990 to 2017: a systematic analysis for the Global Burden of Disease Study. JAMA Oncol, 5, 1749–1768.Google ScholarPubMed
Graham, B. B., Bandeira, A. P., Morrell, N. W., Butrous, G. & Tuder, R. M. 2010. Schistosomiasis-associated pulmonary hypertension: pulmonary vascular disease: the global perspective. Chest, 137, 20S–29S.10.1378/chest.10-0048CrossRefGoogle ScholarPubMed
Ho, A., Aston, S. J., Jary, H. et al. 2018. Impact of human immunodeficiency virus on the burden and severity of influenza illness in Malawian adults: a prospective cohort and parallel case-control study. Clin Infect Dis, 66, 865–876.CrossRefGoogle ScholarPubMed
Jeebhay, M. F. & Quirce, S. 2007. Occupational asthma in the developing and industrialised world: a review [State of the Art Series. Occupational lung disease in high- and low-income countries, Edited by M. Chan-Yeung. Number 1 in the series]. Int J Tuberculosis Lung Dis, 11, 122–133.Google ScholarPubMed
Lois-Correa, J. A., Flores-Vela, A., Ortega-Grimaldo, D. & Berman-Delgado, J. 2010. Experimental evaluation of sugar cane bagasse storage in bales system. J Appl Res Technol, 8, 365–375.10.22201/icat.16656423.2010.8.03.460CrossRefGoogle Scholar
Morrow, B. M., Hsaio, N. Y., Zampoli, M., Whitelaw, A. & Zar, H. J. 2010. Pneumocystis pneumonia in South African children with and without human immunodeficiency virus infection in the era of highly active antiretroviral therapy. Pediatr Infect Dis J, 29, 535–539.10.1097/INF.0b013e3181ce871eCrossRefGoogle ScholarPubMed
Okoi, C., Anderson, S. T. B., Antonio, M., Mulwa, S. N., Gehre, F. & Adetifa, I. M. O. 2017. Non-tuberculous mycobacteria isolated from pulmonary samples in sub-Saharan Africa – a systematic review and meta analyses. Sci Rep, 7, 12002.10.1038/s41598-017-12175-zCrossRefGoogle ScholarPubMed
Rees, D. & Murray, J. 2007. Silica, silicosis and tuberculosis [State of the Art Series. Occupational lung disease in high- and low-income countries, Edited by M. Chan-Yeung. Number 4 in the series]. Int J Tuberculosis Lung Dis, 11, 474–484.Google Scholar
Semeere, A. S., Busakhala, N. & Martin, J. N. 2012. Impact of antiretroviral therapy on the incidence of Kaposi’s sarcoma in resource-rich and resource-limited settings. Curr Opinion Oncol, 24, 522–530.10.1097/CCO.0b013e328355e14bCrossRefGoogle Scholar
Setianingrum, F., Rautemaa-Richardson, R. & Denning, D. W. 2019. Pulmonary cryptococcosis: a review of pathobiology and clinical aspects. Med Mycol, 57, 133–150.CrossRefGoogle ScholarPubMed
Sharp, M. F. & Lopata, A. L. 2014. Fish allergy: in review. Clin Rev Allergy Immunol, 46, 258–271.CrossRefGoogle ScholarPubMed
Urman, A., Josyula, S., Rosenberg, A., Lounsbury, D., Rohan, T. & Hosgood, H. 2016. Burden of lung cancer and associated risk factors in Africa by region. J Pulm Resp Med, 6. doi: 10.4172/2161-105X.1000340.Google Scholar
Walker, S. P., Bibby, A. C., Halford, P., Stadon, L., White, P. & Maskell, N. A. 2018. Recurrence rates in primary spontaneous pneumothorax: a systematic review and meta-analysis. Eur Resp J, 52, 1800864.10.1183/13993003.00864-2018CrossRefGoogle ScholarPubMed
Wasserman, S., Engel, M. E., Griesel, R. & Mendelson, M. 2016. Burden of pneumocystis pneumonia in HIV-infected adults in sub-Saharan Africa: a systematic review and meta-analysis. BMC Infect Dis, 16, 482.10.1186/s12879-016-1809-3CrossRefGoogle ScholarPubMed

References

Acquah, ME, Hsing, AW, McGuire, V et al. (2019). Presentation and survival of multiple myeloma patients in Ghana: a review of 169 cases. Ghana Med J. 53(1):52–58. doi: 10.4314/gmj.v53i1.8.CrossRefGoogle Scholar
Asamoah-Akuoko, L, Hassall, OW, Bates, I et al. (2017). Blood donors’ perceptions, motivators and deterrents in Sub-Saharan Africa – a scoping review of evidence. Br J Haematol 177(6): 864–877 DOI: 10.1111/bjh.14588CrossRefGoogle ScholarPubMed
Asare, EV, Wilson, I, Benneh-Akwasi Kuma, AA et al. (2018). Burden of sickle cell disease in Ghana: the Korle-Bu experience. Adv Hematol. 2018:6161270. doi: 10.1155/2018/6161270. PMID: 30631363; PMCID: PMC6304501.Google ScholarPubMed
Asare, EV, Olayemi, E, Boafor, T et al. (2019). Third trimester and early postpartum period of pregnancy have the greatest risk for ACS in women with SCD. Am J Hematol 94(12):E328–E331. doi: 10.1002/ajh.25643. PMID: 31571271.CrossRefGoogle ScholarPubMed
Bates, I, Chapotera, GK, McKew, S et al. (2008). Maternal mortality in sub-Saharan Africa: the contribution of ineffective blood transfusion services. Brit J Obs Gynae 115:1331–1339.10.1111/j.1471-0528.2008.01866.xCrossRefGoogle ScholarPubMed
Bazuaye, N, Nwogoh, B, Ikponmwen, D et al. (2014). First successful allogeneic hematopoietic stem cell transplantation for a sickle cell disease patient in a low resource country (Nigeria): a case report. Ann Transplant 19:210–213. doi: 10.12659/AOT.890248. PMID: 24792997.Google Scholar
Bedu-Addo, GK, Bates, I (2002). Causes of massive tropical splenomegaly in Ghana. Lancet 360:449–454.10.1016/S0140-6736(02)09680-0CrossRefGoogle ScholarPubMed
Boafor, TK, Olayemi, E, Galadanci, N et al. (2016). Pregnancy outcomes in women with sickle-cell disease in low and high income countries: a systematic review and meta-analysis. Br J Obstet Gynae 123(5):691–698. doi: 10.1111/1471-0528.13786. Epub 2015 Dec 15. PMID: 26667608.CrossRefGoogle ScholarPubMed
Boele, M, Calis, J, Phiri, K et al. (2010). Pathophysiological mechanisms of severe anaemia in Malawian children. PLoS ONE 5:e12589.10.1371/journal.pone.0012589CrossRefGoogle Scholar
Brandow AM, Carroll CP, Creary S et al (2020). American Society of Hematology 2020 guidelines for sickle cell disease: management of acute and chronic pain. Blood Adv (12): 2656–2701.Google Scholar
British Committee for Standards in Haematology (BCSH) (2003). Guidelines for the management of the acute painful crisis in sickle cell disease. Br J Haematol 120:744–752.10.1046/j.1365-2141.2003.04193.xCrossRefGoogle Scholar
Calis, JC, Phiri, KS, Faragher, EB et al. (2008). Severe anemia in Malawian children. N Engl J Med 358:888–899.10.1056/NEJMoa072727CrossRefGoogle ScholarPubMed
Durosinmi, MA, Faluyi, JO, Oyekunle, AA et al. (2008). The use of imatinib mesylate in Nigerians with chronic myeloid leukemia. Cell Ther Transpl 2: 15.Google Scholar
English, M, Ahmed, M, Ngando, C et al. (2002). Blood transfusion for severe anaemia in children in a Kenyan hospital. Lancet 359:494–495.10.1016/S0140-6736(02)07666-3CrossRefGoogle Scholar
Fakunle, EE, Shokunbi, WA, Shittu, OB (2007). Incidence of factor FVIIIC deficiency in live male infants undergoing circumcision in South West, Nigeria. Haemophilia 13:567–569.10.1111/j.1365-2516.2007.01549.xCrossRefGoogle ScholarPubMed
Fleming, AE, de Silva, PS (2003). Haematological diseases in the tropics. In Cook, GC, Zumla, A (eds) Manson’s Tropical Diseases. 21st ed., 169–243. London: W.B. Saunders.Google Scholar
Friedman, JF, Kanzaria, HK, McGarvey, ST (2005). Human schistosomiasis and anemia: the relationship and potential mechanisms. Trends Parasitol 21: 386–392.10.1016/j.pt.2005.06.006CrossRefGoogle ScholarPubMed
Hassall, O, Maitland, K, Pole, L et al. (2009). Bacterial contamination of pediatric whole blood transfusions in a Kenyan hospital. Transfusion 49: 2594–2598.10.1111/j.1537-2995.2009.02344.xCrossRefGoogle Scholar
Khan, KS, Wojdyla, D, Say, L et al. (2006). WHO analysis of causes of maternal death: a systematic review. Lancet 367: 1066–1074.CrossRefGoogle ScholarPubMed
Lulseged, S (1993). Haemorrhagic disease of the newborn: a review of 127 cases. Ann Trop Paediatr 13:331–336.10.1080/02724936.1993.11747666CrossRefGoogle ScholarPubMed
Mahlangu, JN (2009). Haemophilia care in South Africa: 2004–2007 look back. Haemophilia 15:135–141.10.1111/j.1365-2516.2008.01807.xCrossRefGoogle ScholarPubMed
Maitland, K, Pamba, A, English, M et al. (2005). Pre-transfusion management of children with severe malarial anaemia: a randomised controlled trial of intravascular volume expansion. Br J Haematol 128: 393–400.10.1111/j.1365-2141.2004.05312.xCrossRefGoogle ScholarPubMed
Maitland K for the TRACT trial group (2019). Transfusion volume for children with severe anemia in Africa. N Engl J Med 381:420–431.10.1056/NEJMoa1900100CrossRefGoogle Scholar
Martin-Peprah, R, Bates, I, Bedu-Addo, G et al. (2006). Investigation of familial segregation of hyperreactive malarial splenomegaly in Kumasi, Ghana. Trans R Soc Trop Med Hyg 100:68–73.10.1016/j.trstmh.2005.07.006CrossRefGoogle ScholarPubMed
Mbanya, D, Binam, F, Kaptue, L (2001). Transfusion outcome in a resource-limited setting of Cameroon: a five-year evaluation. Int J Infect Dis 5:70–73.10.1016/S1201-9712(01)90028-1CrossRefGoogle Scholar
Menendez, C, Fleming, AF, Alonso, PL (2000). Malaria related anaemia. Parasitol Today 16:469–476.10.1016/S0169-4758(00)01774-9CrossRefGoogle ScholarPubMed
Mitchell, C, Hall, G, Clarke, RT (2009). Acute leukaemia in children: diagnosis and management. Br Med J 338:b2285.Google Scholar
Mosha, D, Poulsen, A, Reyburn, H et al. (2009). Quality of paediatric blood transfusions in two district hospitals in Tanzania: a cross-sectional hospital based study. BMC Pediatr 9:51.10.1186/1471-2431-9-51CrossRefGoogle ScholarPubMed
Mukwala, EC, Banda, J, Siziya, S et al. (1989). Alpha thalassaemia in Zambian newborn. Clin Laborat Haematol 11:1–6.10.1111/j.1365-2257.1989.tb00167.xCrossRefGoogle Scholar
Omoti, CE, Halim, NK (2005). Adult lymphomas in Edo state, Niger Delta region of Nigeria – clinicopathological profile of 205 cases. Clin Lab Haematol 27:302–306.10.1111/j.1365-2257.2005.00711.xCrossRefGoogle ScholarPubMed
Omoti, CE, Omuemu, CE (2007). Multiple myeloma: a ten year study of survival and therapy in a developing nation. J Pak Med Assoc 57:341–344.Google Scholar
Oppong, SA, Asare, EV, Olayemi, E et al. (2019). Multidisciplinary care results in similar maternal and perinatal mortality rates for women with and without SCD in a low-resource setting. Am J Hematol 94(2):223–230. doi: 10.1002/ajh.25356.CrossRefGoogle Scholar
Ord RL, Lobo CA (2015). Human babesiosis: Pathogens, prevalence, diagnosis and treatment. Curr Clin Microbiol Rep (4):173–181.Google Scholar
Payne JN, Gee BE (2024). Management of acute sickle cell disease pain. Pediatr Rev 45(1):26–38.Google Scholar
Phiri, K, Calis, JCJ, Siyasiya, A et al. (2009). New cut off levels for ferritin and soluble transferrin receptor for the assessment of iron deficiency in children in a high infection pressure area. J Clin Path 62: 1103–1106.10.1136/jcp.2009.066498CrossRefGoogle Scholar
Roberts, LN (2021). Rebalanced hemostasis in liver disease: a misunderstood coagulopathy. Hematology. American Society of Hematology. Education Program 2021(1):485–491.10.1182/hematology.2021000283CrossRefGoogle ScholarPubMed
Rubinstein, R, Kolia, F, Novitzky, N (2000).Prevalence of Factor V Leiden in three ethnic groups of patients with deep vein thrombosis in the Western Cape province of South Africa. Eur J Haematol 65:78–79.10.1034/j.1600-0609.2000.9c168.xCrossRefGoogle ScholarPubMed
Stoffel, NU, Zeder, C, Brittenham, GM et al. (2020). Iron absorption from supplements is greater with alternate day than with consecutive day dosing in iron-deficient anemic women. Haematologica 105(5):1232–1239. doi.org/10.3324/haematol.2019.220830CrossRefGoogle ScholarPubMed
Tezanos, PM, Ortiz, Z (2004). Haemophilia in the developing world: successes, frustrations and opportunities. Haemophilia 10:S14–19.10.1111/j.1365-2516.2004.00986.xCrossRefGoogle Scholar
Violi, F, Corazza, GR, Caldwell, SH et al. (2019). PRO-LIVER Collaborative Group. Incidence and recurrence of portal vein thrombosis in cirrhotic patients. Thromb Haemost 119(3):496–499. doi: 10.1055/s-0038-1676981.Google Scholar
von Meijenfeldt, FA, van den Boom, BP, Adelmeijer, J et al. (2021). Prophylactic fresh frozen plasma and platelet transfusion have a prothrombotic effect in patients with liver disease. J Thromb Haemost 19(3):664–676. doi:10.1111/jth.15185.CrossRefGoogle ScholarPubMed
Ware, RE, Davis, BR, Schultz, WH et al. (2016). Hydroxycarbamide versus chronic transfusion for maintenance of transcranial doppler flow velocities in children with sickle cell anaemia-TCD With Transfusions Changing to Hydroxyurea (TWiTCH): a multicentre, open-label, phase 3, non-inferiority trial. Lancet 387(10019):661–670.10.1016/S0140-6736(15)01041-7CrossRefGoogle ScholarPubMed
Weatherall, DJ (2008). Genetic variation and susceptibility to infection: the red cell and malaria. Br J Haematol 141:276–286.10.1111/j.1365-2141.2008.07085.xCrossRefGoogle ScholarPubMed
White, NJ (2018). Anaemia and malaria. Malar J 17:371. doi.org/10.1186/s12936-018-2509-9CrossRefGoogle ScholarPubMed
WHO (2001). The prevention and management of severe anaemia in children in malaria-endemic regions of Africa. Geneva: WHO.Google Scholar
WHO (2016). Global Status Report on Blood Safety and Availability (2016) https://apps.who.int/iris/bitstream/handle/10665/254987/9789241565431-eng.pdf?sequence=1.Google Scholar
WHO (2018). Fact sheet: blood safety and availability. www.who.int/news-room/fact-sheets/detail/blood-safety-and-availability.Google Scholar
WHO/NHD (2001). Iron deficiency anaemia: assessment, prevention and control. Geneva: WHO.Google Scholar
Williams, TN, Uyoga, S, Macharia, A et al. (2009). Bacteraemia in Kenyan children with sickle-cell anaemia: a retrospective cohort and case-control study. Lancet 374:1364–1370.10.1016/S0140-6736(09)61374-XCrossRefGoogle ScholarPubMed
Wun T (2001). The role of inflammation and leukocytes in the pathogenesis of sickle cell disease. Haemoglobinopathy. Hematology 5(5):403–412.Google Scholar

References

Archampong, TN, Asmah, RH, Richards, CJ et al. (2019). Gastro-duodenal disease in Africa: literature review and clinical data from Accra, Ghana. World J Gastroenterol 25(26):3344–3358.10.3748/wjg.v25.i26.3344CrossRefGoogle ScholarPubMed
Banks, M, Graham, D, Jansen, M et al. (2019). British Society of Gastroenterology guidelines on the diagnosis and management of patients at risk of gastric adenocarcinoma. Gut 68(9):1545–1575.10.1136/gutjnl-2018-318126CrossRefGoogle ScholarPubMed
Black, CJ, Thakur, ER, Houghton, LA et al. (2020). Efficacy of psychological therapies for irritable bowel syndrome: systematic review and network meta-analysis. Gut 69(8):1441–1451.10.1136/gutjnl-2020-321191CrossRefGoogle ScholarPubMed
Dawsey, SP, Tonui, S, Parker, RK et al. (2010). Esophageal cancer in young people: a case series of 109 cases and review of the literature. PLoS One 22;5(11):e14080.10.1371/journal.pone.0014080CrossRefGoogle Scholar
Ferlay, J, Ervik, M, Lam, F et al. (2020). Global Cancer Observatory: Cancer Today. Lyon, France: International Agency for Research on Cancer. https://gco.iarc.fr/today.Google Scholar
Gravina, AG, Zagari, RM, De Musis, C et al. (2018). Helicobacter pylori and extragastric diseases: A review. World J Gastroenterol 24(29):3204–3221.10.3748/wjg.v24.i29.3204CrossRefGoogle ScholarPubMed
Hodges, P, Kelly, P. (2020). Inflammatory bowel disease in Africa: what is the current state of knowledge? Int Health 12(3):222–230.10.1093/inthealth/ihaa005CrossRefGoogle Scholar
Jaka, H, Rhee, JA, Östlundh, L et al. (2018). The magnitude of antibiotic resistance to Helicobacter pylori in Africa and identified mutations which confer resistance to antibiotics: systematic review and meta-analysis. BMC Infect Dis 18(1):193.10.1186/s12879-018-3099-4CrossRefGoogle ScholarPubMed
Kayamba, V, Mutale, W, Cassell, H et al. (2021). Systematic review of cancer research output from Africa, with Zambia as an example. JCO Glob Oncol 7:802–810.10.1200/GO.21.00079CrossRefGoogle ScholarPubMed
Kayamba, V, Sinkala, E, Mwanamakondo, S et al. (2015). Trends in upper gastrointestinal diagnosis over four decades in Lusaka, Zambia: a retrospective analysis of endoscopic findings. BMC Gastroenterol 15:127.CrossRefGoogle ScholarPubMed
Kayamba, V, Zyambo, K, Mulenga, C et al. (2020). Biomass smoke exposure is associated with gastric cancer and probably mediated via oxidative stress and DNA damage: a case-control study. JCO Glob Oncol 6:532–541.CrossRefGoogle ScholarPubMed
Kelly, P, Katema, M, Amadi, B et al. (2008). Gastrointestinal pathology in the University Teaching Hospital, Lusaka, Zambia: review of endoscopic and pathology records. Trans R Soc Trop Med Hyg 102(2):194–199.10.1016/j.trstmh.2007.10.006CrossRefGoogle ScholarPubMed
Malfertheiner, P, Megraud, F, O’Morain, CA et al. (2017). Management of Helicobacter pylori infection – the Maastricht V/Florence Consensus Report. Gut 66(1):6–30.10.1136/gutjnl-2016-312288CrossRefGoogle ScholarPubMed
Mushi, BP, Mwachiro, MM, Buckle, G et al. (2021). Improving access to self-expanding metal stents for patients with esophageal cancer in eastern Africa: a stepwise implementation strategy. JCO Glob Oncol 7:118–126.CrossRefGoogle ScholarPubMed
Ofosu, A, Mohan, BP, Ichkhanian, Y et al. (2021). Peroral endoscopic myotomy (POEM) vs pneumatic dilation (PD) in treatment of achalasia: a meta-analysis of studies with ≥ 12-month follow-up. Endosc Int Open 9(7):E1097–E1107.10.1055/a-1483-9406CrossRefGoogle ScholarPubMed
Paruk, IM, Naidoo, VG, Pirie, FJ et al. (2019). Prevalence and characteristics of celiac disease in South African patients with type 1 diabetes mellitus: results from the Durban Diabetes and Celiac Disease Study. J Gastroenterol Hepatol 34(4):673–678.10.1111/jgh.14596CrossRefGoogle ScholarPubMed
Unnikrishnan, R, Mohan, V. (2015). Fibrocalculous pancreatic diabetes (FCPD). Acta Diabetol 52(1):1–9.10.1007/s00592-014-0685-9CrossRefGoogle ScholarPubMed
Watermeyer, G, Epstein, D, Adegoke, O et al. (2020). Epidemiology of inflammatory bowel disease in sub-Saharan Africa: a review of the current status. S Afr Med J 110(10):1006–1009.10.7196/SAMJ.2020.v110i10.14489CrossRefGoogle ScholarPubMed

References

Acharya, C., Bajaj, J.S. 2018. Current management of hepatic encephalopathy. American Journal of Gastroenterology 113, 1600–1612. doi.org/10.1038/s41395-018-0179-4.CrossRefGoogle ScholarPubMed
Agarwal, B., Wright, G., Gatt, A. et al. 2012. Evaluation of coagulation abnormalities in acute liver failure. Journal of Hepatology 57, 780–786. doi.org/10.1016/j.jhep.2012.06.020.CrossRefGoogle ScholarPubMed
Agbaji, O.O., Ladep, N.G., Agaba, P. et al. 2008. Prevalence and characteristics of hepatitis B surface antigenaemia among HIV infected patients in Jos, Nigeria. Hungarian Medical Journal 2, 77–82.10.1556/HMJ.2.2008.1.9CrossRefGoogle Scholar
Aithal, G.P., Palaniyappan, N., China, L. et al. 2021. Guidelines on the management of ascites in cirrhosis. Gut 70, 9–29. doi.org/10.1136/gutjnl-2020-321790.CrossRefGoogle ScholarPubMed
Alvarez, M.A., Cirera, I., Solà, R., Bargalló, A., Morillas, R.M., Planas, R. 2011. Long-term clinical course of decompensated alcoholic cirrhosis: a prospective study of 165 patients. Journal of Clinical Gastroenterology 45, 906–911. doi.org/10.1097/MCG.0b013e3182284e13.CrossRefGoogle ScholarPubMed
Angeli, P., Bernardi, M., Villanueva, C. et al. 2018. EASL Clinical Practice Guidelines for the management of patients with decompensated cirrhosis. Journal of Hepatology 69, 406–460. doi.org/10.1016/j.jhep.2018.03.024.CrossRefGoogle Scholar
Angeli, P., Wong, F., Watson, H., Ginès, P., Investigators, CAPPS 2006. Hyponatremia in cirrhosis: results of a patient population survey. Hepatology 44, 1535–1542. doi.org/10.1002/hep.21412.CrossRefGoogle ScholarPubMed
Bagulo, H., Majekodunmi, A.O., Welburn, S.C. 2020. Hepatitis E in sub Saharan Africa – a significant emerging disease. One Health 11, 100186. doi.org/10.1016/j.onehlt.2020.100186.CrossRefGoogle ScholarPubMed
Bittencourt, P.L., Farias, A.Q., Strauss, E., Mattos, A.A. de 2010. Variceal bleeding: consensus meeting report from the Brazilian Society of Hepatology. Arquivos de Gastroenterologia 47, 202–216. doi.org/10.1590/S0004-28032010000200017.CrossRefGoogle ScholarPubMed
Chatterjee, S., Van Marck, E. 2001. The role of somatostatin in schistosomiasis: a basis for immunomodulation in host-parasite interactions? Trop Med Int Health 6, 578–581. doi.org/10.1046/j.1365-3156.2001.00758.x.Google ScholarPubMed
Cribier, B., Petian, P., Keller, F. et al. (1995). Porphyria cutanea tarda and hepatitis C viral infection. A clinical and virological study. Arch Dermatol 131, 801–804.10.1001/archderm.1995.01690190055010CrossRefGoogle Scholar
Dorrucci, M., Pezzotti, P., Phillips, A.N. et al. (1995). Coinfection of hepatitis C virus with human immunodeficiency virus and progression of AIDS. Italian Seroconversion Study. Journal of Infectious Diseases 172, 1503–1508.10.1093/infdis/172.6.1503CrossRefGoogle ScholarPubMed
Farias, A.Q., Kassab, F., da Rocha, E.C.V. et al. 2009. Propranolol reduces variceal pressure and wall tension in schistosomiasis presinusoidal portal hypertension. Journal of Gastroenterology and Hepatology 24, 1852–1856. doi.org/10.1111/j.1440-1746.2009.05912.x.CrossRefGoogle ScholarPubMed
Fenwick, A., Webster, J.P., Bosque-Oliva, E. et al. 2009. The Schistosomiasis Control Initiative (SCI): rationale, development and implementation from 2002–2008. Parasitology 136, 1719–1730. doi.org/10.1017/S0031182009990400.CrossRefGoogle ScholarPubMed
Frean, J., Innis, B.L., He, J., Seriwatana, J., Isaäcson, M. 2000. An outbreak of hepatitis E in Northern Namibia, 1983. American Journal of Tropical Medicine and Hygiene 62, 619–625. doi.org/10.4269/ajtmh.2000.62.619.Google Scholar
Galle, P.R., Foerster, F., Kudo, M. et al. 2019. Biology and significance of alpha‐fetoprotein in hepatocellular carcinoma. Liver International 39, 2214–2229. doi.org/10.1111/liv.14223.CrossRefGoogle ScholarPubMed
Gangaidzo, I.T., Gordeuk, V.R. (1995). Hepatocellular carcinoma and African iron overload. Gut 37, 727–730.10.1136/gut.37.5.727CrossRefGoogle ScholarPubMed
Garcia-Tsao, G., Sanyal, A.J., Grace, N.D., Carey, W., Practice Guidelines Committee of the American Association for the Study of Liver Diseases, the Practice Parameters Committee of the American College of Gastroenterology 2007. Prevention and management of gastroesophageal varices and variceal hemorrhage in cirrhosis. Hepatology 46, 922–938. doi.org/10.1002/hep.21907.CrossRefGoogle ScholarPubMed
Gilson, RJ, Hawkins, AE, Beecham, MR et al. (1997). Interaction between HIV and hepatitis B in homosexual men: effects on the natural history of infection. AIDS 11, 597–606.10.1097/00002030-199705000-00007CrossRefGoogle ScholarPubMed
Gunda, D.W., Kilonzo, S.B., Manyiri, P.M., Peck, R.N., Mazigo, H.D. 2020. Morbidity and mortality due to Schistosoma mansoni related periportal fibrosis: could early diagnosis of varices improve the outcome following available treatment modalities in sub Saharan Africa? A scoping review. Tropical Medicine 5, 20. doi.org/10.3390/tropicalmed5010020.Google ScholarPubMed
Hennig, B.J., Hall, A.J. (2012). Host genetic factors in hepatitis B infection, liver cancer and vaccination response: a review with a focus on Africa. Science of the Total Environment 423, 202–209.10.1016/j.scitotenv.2010.09.036CrossRefGoogle ScholarPubMed
Jobarteh, M., Malfroy, M., Peterson, I. et al. 2010. Seroprevalence of hepatitis B and C virus in HIV-1 and HIV-2 infected Gambians. Virology Journal 15, 230.CrossRefGoogle Scholar
Khanna, R., Sarin, S.K. 2019. Noncirrhotic portal hypertension. Clinics in Liver Disease 23, 781–807. doi.org/10.1016/j.cld.2019.07.006.CrossRefGoogle ScholarPubMed
Kiire, CE, Gombe-Mbalawa, C, Tsega, E et al. 1992. Multicentre study of the treatment of primary liver cancer in Africa with two anthracycline drugs. Central African Journal of Medicine 38, 428–431.Google ScholarPubMed
Kong, D.-R. 2013. Effects of propranolol or propranolol plus isosorbide-5-mononitrate on variceal pressure in schistosomiasis. World Journal of Gastroenterology 19, 4228. doi.org/10.3748/wjg.v19.i26.4228.CrossRefGoogle ScholarPubMed
Kossard, A.A., Lindor, K.D. 2000. Medical management of chronic cholestatic liver diseases. Canadian Journal of Gastroenterology 14, D1–D98.Google Scholar
Kramvis, A., Kew, M.C. 2007. Epidemiology of hepatitis B virus in Africa, its genotypes and clinical associations of genotypes. Hepatology Research 37, S9–S19. doi.org/10.1111/j.1872-034X.2007.00098.x.CrossRefGoogle ScholarPubMed
Lampertico, P., Agarwal, K., Berg, T. et al. 2017. EASL 2017 Clinical Practice Guidelines on the management of hepatitis B virus infection. Journal of Hepatology 67, 370–398. doi.org/10.1016/j.jhep.2017.03.021.CrossRefGoogle Scholar
Leber, B., Spindelboeck, W., Stadlbauer, V. 2012. Infectious complications of acute and chronic liver disease. Seminars in Respiratory and Critical Care Medicine 33, 80–95. doi.org/10.1055/s-0032-1301737.Google ScholarPubMed
Lee, W.M., Stravitz, R.T., Larson, A.M. 2012. Introduction to the revised American Association for the Study of Liver Diseases position paper on acute liver failure 2011. Hepatology 55, 965–967. doi.org/10.1002/hep.25551.CrossRefGoogle Scholar
Martins, R.D., Szejnfeld, J., Lima, F.G., Ferrari, A.P. 2000. Endoscopic, ultrasonographic, and US-Doppler parameters as indicators of variceal bleeding in patients with schistosomiasis. Digestive Diseases and Sciences 45, 1013–1018. doi.org/10.1023/a:1005501930808.CrossRefGoogle ScholarPubMed
Moore, K. 2003. The management of ascites in cirrhosis: report on the consensus conference of the International Ascites Club. Hepatology 38, 258–266. doi.org/10.1053/jhep.2003.50315.CrossRefGoogle ScholarPubMed
Olinger, C.M., Venard, V., Njayou, M. et al. 2006. Phylogenetic analysis of the precore/core gene of hepatitis B virus genotypes E and A in West Africa: new subtypes, mixed infections and recombinations. Journal of General Virology 87, 1163–1173. doi.org/10.1099/vir.0.81614-0.CrossRefGoogle Scholar
Peto, T.J., Mendy, M.E., Lowe, Y. et al. 2014. Efficacy and effectiveness of infant vaccination against chronic hepatitis B in the Gambia Hepatitis Intervention Study (1986–90) and in the nationwide immunisation program. BMC Infectious Diseases 14, 7.10.1186/1471-2334-14-7CrossRefGoogle ScholarPubMed
Powell, W.J., Klatskin, G. 1968. Duration of survival in patients with Laennec’s cirrhosis. American Journal of Medicine 44, 406–420. doi.org/10.1016/0002-9343(68)90111-3.CrossRefGoogle ScholarPubMed
Schoental, R., Coady, A. 1968. The hepatotoxicity of some Ethiopian and East African plants, including some used in traditional medicine. East African Medical Journal 45, 577–800.Google Scholar
Scott, T.R. 2013. Pathophysiology of cerebral oedema in acute liver failure. World Journal of Gastroenterology 19, 9240. doi.org/10.3748/wjg.v19.i48.9240.CrossRefGoogle ScholarPubMed
Sersté, T., Gustot, T., Rautou, P.-E. et al. 2012. Severe hyponatremia is a better predictor of mortality than MELDNa in patients with cirrhosis and refractory ascites. Journal of Hepatology 57, 274–280. doi.org/10.1016/j.jhep.2012.03.018.CrossRefGoogle ScholarPubMed
Shim, J.H., Lee, H.C., Kim, K.M. et al. 2010. Efficacy of entecavir in treatment-naïve patients with hepatitis B virus-related decompensated cirrhosis. Journal of Hepatology 52, 176–182. doi.org/10.1016/j.jhep.2009.11.007.CrossRefGoogle ScholarPubMed
Siniscalchi, A., Dante, A., Spedicato, S. et al. 2010. Hyperdynamic circulation in acute liver failure: reperfusion syndrome and outcome following liver transplantation. Transplantation Proceedings 42, 1197–1199. doi.org/10.1016/j.transproceed.2010.03.097.CrossRefGoogle ScholarPubMed
Sinkala, E., Kapulu, M.C., Besa, E. et al. 2016a. Hepatosplenic schistosomiasis is characterised by high blood markers of translocation, inflammation and fibrosis. Liver International 36, 145–150. doi.org/10.1111/liv.12891.CrossRefGoogle ScholarPubMed
Sinkala, E., Kapulu, M.C., Besa, E. et al. 2016b. Hepatosplenic schistosomiasis is characterised by high blood markers of translocation, inflammation and fibrosis. Liver International 36, 145–150. doi.org/10.1111/liv.12891.CrossRefGoogle ScholarPubMed
Sinkala, E., Vinikoor, M., Miyanda Siyunda, A. et al. 2020a. Hepatosplenic schistosomiasis in Zambian adults is characterized by increased liver stiffness: a nested case-control study. Heliyon 6, e04534. doi.org/10.1016/j.heliyon.2020.e04534.CrossRefGoogle ScholarPubMed
Sinkala, E., Vinikoor, M., Zyambo, K., Besa, E., Nsokolo, B., Kelly, P. 2020b. Propranolol reduces portal vein diameter in schistosomal liver disease with portal hypertension: a prospective cohort study. American Journal of Tropical Medicine and Hygiene 102, 832–837. doi.org/10.4269/ajtmh.19-0452.CrossRefGoogle ScholarPubMed
Sinkala, E., Zyambo, K., Besa, E. et al. 2018. Rifaximin reduces markers of inflammation and bacterial 16S rRNA in Zambian adults with hepatosplenic schistosomiasis: a randomized control trial. American Journal of Tropical Medicine and Hygiene 98, 1152–1158. doi.org/10.4269/ajtmh.17-0637.CrossRefGoogle Scholar
Stanley, A.J., Laine, L. 2019. Management of acute upper gastrointestinal bleeding. British Medical Journal l536. doi.org/10.1136/bmj.l536.CrossRefGoogle Scholar
Strauss, E., Valla, D. 2014. Non-cirrhotic portal hypertension – concept, diagnosis and clinical management. Clinics and Research in Hepatology and Gastroenterology 38, 564–569. doi.org/10.1016/j.clinre.2013.12.012.CrossRefGoogle ScholarPubMed
Tangkijvanich, P., Anukulkarnkusol, N., Suwangool, P. et al. 2000. Clinical characteristics and prognosis of hepatocellular carcinoma: analysis based on serum alpha-fetoprotein levels. Journal of Clinical Gastroenterology 31, 302–308. doi.org/10.1097/00004836-200012000-00007.CrossRefGoogle ScholarPubMed
Tsebe, K.V., Burnett, R.J., Jlungwani, N.P., Sibara, M.M., Venter, P.A., Mphahlele, M.J. 2001. The first five years of universal hepatitis B vaccination in South Africa: evidence for elimination of HbsAg carriage in under 5 years olds. Vaccine 19, 3919–3926.10.1016/S0264-410X(01)00120-7CrossRefGoogle Scholar
Tsega, E., Krawczynksi, K., Hansson, B.- G. et al. 1993. Hepatitis E virus infection in pregnancy in Ethiopia. Ethiopian Medical Journal 31, 173–181.Google ScholarPubMed
Tsega, E., Nordenfelt, E., Hansson, B.G. 1995. Hepatitis C virus infection and chronic liver disease in Ethiopia where hepatitis B infection is hyperendemic. Transactions of the Royal Society of Tropical Medicine & Hygiene 89, 171–174.10.1016/0035-9203(95)90482-4CrossRefGoogle ScholarPubMed
Umoh, N.J., Lesi, O.A., Mendy, M. et al. 2011. Aetiological differences in demographical, clinical and pathological characteristics of hepatocellular carcinoma in The Gambia. Liver International 31, 215–221.10.1111/j.1478-3231.2010.02418.xCrossRefGoogle ScholarPubMed
Ungo, J.R., Jones, D., Ashkin, D. et al. 1998. Antituberculosis drug-induced hepatotoxicity. The role of hepatitis C virus and the human immunodeficiency virus. American Journal of Respiratory and Critical Care Medicine 157, 1871–1876.10.1164/ajrccm.157.6.9711039CrossRefGoogle ScholarPubMed
Vento, S., Garofano, T., Renzini, C. et al. 1998. Fulminant hepatitis associated with hepatitis A virus superinfection in patients with chronic hepatitis C. New England Journal of Medicine 338, 286–290.CrossRefGoogle ScholarPubMed
Wang, D.-W. 2013. Advances in the management of acute liver failure. World Journal of Gastroenterology 19, 7069. doi.org/10.3748/wjg.v19.i41.7069.CrossRefGoogle ScholarPubMed
Wang, J.Y., Bajaj, J.S., Wang, J.B. et al. 2019. Lactulose improves cognition, quality of life, and gut microbiota in minimal hepatic encephalopathy: a multicenter, randomized controlled trial. Journal of Digestive Diseases 20, 547–556. doi.org/10.1111/1751-2980.12816.CrossRefGoogle ScholarPubMed
WHO 2013. Schistosomiasis: progress report 2001–2011, strategic plan 2012–2020. Geneva: WHO.Google Scholar
Ziraba, A.K., Bwogi, J., Namale, A., Wainaina, C.W., Mayanja-Kizza, H. 2010. Sero-prevalence and risk factors for hepatitis B virus infection among health care workers in a tertiary hospital in Uganda. BMC Infectious Diseases 10, 191. doi.org/10.1186/1471-2334-10-191.CrossRefGoogle Scholar

Bibliography

Abdelrahman, M., Sinha, A. K. & Karkar, A. (2006) Tuberculosis in end-stage renal disease patients on hemodialysis. Hemodialysis International. doi: 10.1111/j.1542-4758.2006.00130.x.CrossRefGoogle Scholar
Al-Efraij, K. et al. (2015) Risk of active tuberculosis in chronic kidney disease: a systematic review and meta-analysis. International Journal of Tuberculosis and Lung Disease. doi: 10.5588/ijtld.15.0081.CrossRefGoogle Scholar
Andrade, L., de Francesco Daher, E. & Seguro, A. C. (2008) Leptospiral nephropathy. Seminars in Nephrology, 28(4). doi: 10.1016/j.semnephrol.2008.04.008.CrossRefGoogle ScholarPubMed
Anochie, I. & Eke, F. (2003) Chronic renal failure in children: a report from Port Harcourt, Nigeria (1985–2000). Pediatric Nephrology. doi: 10.1007/s00467-003-1150-0.CrossRefGoogle Scholar
Arogundade, F. A. et al. (2016) Spectrum of kidney diseases in Africa: Malaria, schistosomiasis, sickle cell disease, and toxins. Clinical Nephrology. doi: 10.5414/CNP86S120.CrossRefGoogle Scholar
Bae, K. T. et al. (2006) Magnetic resonance imaging evaluation of hepatic cysts in early autosomal-dominant polycystic kidney disease: the Consortium for Radiologic Imaging Studies of Polycystic Kidney Disease cohort. Clinical Journal of the American Society of Nephrology. doi: 10.2215/CJN.00080605.CrossRefGoogle Scholar
Bargman, J. M., Thorpe, K. E. & Churchill, D. N. (2001) Relative contribution of residual renal function and peritoneal clearance to adequacy of dialysis: a reanalysis of the CANUSA study. Journal of the American Society of Nephrology. doi: 10.1681/asn.v12102158.CrossRefGoogle Scholar
Barsoum, R. S. (2013) Parasitic kidney disease: milestones in the evolution of our knowledge. American Journal of Kidney Diseases. doi: 10.1053/j.ajkd.2012.09.025.CrossRefGoogle Scholar
Bello, A. K. et al. (2017) Assessment of global kidney health care status. Journal of the American Medical Association. doi: 10.1001/jama.2017.4046.CrossRefGoogle Scholar
Bhimma, R. et al. (2008) The spectrum of chronic kidney disease (stages 2–5) in KwaZulu-Natal, South Africa. Pediatric Nephrology. doi: 10.1007/s00467-008-0871-5.CrossRefGoogle Scholar
Brown, D. D. et al. (2020) Malaria and acute kidney injury. Pediatric Nephrology. doi: 10.1007/s00467-018-4191-0.CrossRefGoogle Scholar
Bukabau, J. B. et al. (2019) Performance of creatinine- or cystatin C–based equations to estimate glomerular filtration rate in sub-Saharan African populations. Kidney International. doi: 10.1016/j.kint.2018.11.045.CrossRefGoogle Scholar
Cadnapaphornchai, M. A. et al. (2014) Effect of pravastatin on total kidney volume, left ventricular mass index, and microalbuminuria in pediatric autosomal dominant polycystic kidney disease. Clinical Journal of the American Society of Nephrology. doi: 10.2215/CJN.08350813.CrossRefGoogle Scholar
Caillard, S. et al. (2021) Is COVID-19 infection more severe in kidney transplant recipients? American Journal of Transplantation 21(3). doi: 10.1111/ajt.16424.CrossRefGoogle ScholarPubMed
Capone, V. P. et al. (2017) Genetics of congenital anomalies of the kidney and urinary tract: the current state of play. International Journal of Molecular Sciences. doi: 10.3390/ijms18040796.CrossRefGoogle Scholar
Centers for Disease Control, (2021) Malaria. www.cdc.gov/parasites/malaria/.Google Scholar
Chapman, A. B. et al. (2015) Autosomal-dominant polycystic kidney disease (ADPKD): Executive summary from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference. Kidney International. doi: 10.1038/ki.2015.59.CrossRefGoogle Scholar
Cohen, D. B., Allain, T. J., Glover, S. et al. (2010) A survey of the management, control and complications of diabetes mellitus in patients attending a diabetes clinic in Blantyre, Malawi – an area of high HIV prevalence. American Journal of Tropical Medicine and Hygiene 83, 575–81.10.4269/ajtmh.2010.10-0104CrossRefGoogle ScholarPubMed
Cornec-Le Gall, E., Alam, A. & Perrone, R. D. (2019) Autosomal dominant polycystic kidney disease. Lancet. doi: 10.1016/S0140-6736(18)32782-X.CrossRefGoogle Scholar
Cullis, B. et al. (2021) ISPD guidelines for peritoneal dialysis in acute kidney injury: 2020 update (adults). Peritoneal Dialysis International 41(1),15–31. doi: 10.1177/0896860820970834.CrossRefGoogle ScholarPubMed
Cullis, B. et al. (2021) Special Series/Guidelines ISPD guidelines for peritoneal dialysis in acute kidney injury: 2020 update (adults). doi: 10.1177/0896860820970834.CrossRefGoogle Scholar
Dutra, M. et al. (1985) Renal involvement in visceral leishmaniasis. American Journal of Kidney Diseases. doi: 10.1016/S0272-6386(85)80034-2.CrossRefGoogle Scholar
Eastwood, J. B. et al. (2010) Assessment of GFR by four methods in adults in Ashanti, Ghana: the need for an eGFR equation for lean African populations. Nephrology Dialysis Transplantation. doi: 10.1093/ndt/gfp765.CrossRefGoogle Scholar
Eastwood, J. B., Corbishley, C. M. & Grange, J. M. (2001) Tuberculosis and the kidney. Journal of the American Society of Nephrology. doi: 10.1681/asn.v1261307.CrossRefGoogle Scholar
Ekrikpo, U. E. et al. (2018) Chronic kidney disease in the global adult HIV-infected population: a systematic review and meta-analysis. PLoS ONE. doi: 10.1371/journal.pone.0195443.CrossRefGoogle Scholar
Elkinton, J.R. & Danowski, T. S. (1955) The body fluids. basic physiology and practical therapeutics. Baltimore: Williams and Wilkins.Google Scholar
Evans, R. D. R. et al. (2017) Incidence, aetiology and outcome of community-acquired acute kidney injury in medical admissions in Malawi. BMC Nephrology 18(1). doi: 10.1186/s12882-017-0446-4.CrossRefGoogle ScholarPubMed
Flores-Mireles, A. L. et al. (2015) Urinary tract infections: epidemiology, mechanisms of infection and treatment options. Nature Reviews Microbiology. doi: 10.1038/nrmicro3432.CrossRefGoogle Scholar
Gansevoort, R. T. et al. (2016) Recommendations for the use of tolvaptan in autosomal dominant polycystic kidney disease: a position statement on behalf of the ERA-EDTA Working Groups on Inherited Kidney Disorders and European Renal Best Practice. Nephrology Dialysis Transplantation. doi: 10.1093/ndt/gfv456.CrossRefGoogle Scholar
Gill, K. et al. (2016) Hepatitis C virus as a systemic disease: reaching beyond the liver. Hepatology International. doi: 10.1007/s12072-015-9684-3.CrossRefGoogle Scholar
Gonzalez Suarez, M. L. et al. (2019) Renal disorders in pregnancy: core curriculum (2019) American Journal of Kidney Diseases. doi: 10.1053/j.ajkd.2018.06.006.CrossRefGoogle Scholar
Gupta, A. & Quigg, R. J. (2015) Glomerular diseases associated with hepatitis B and C. Advances in Chronic Kidney Disease. doi: 10.1053/j.ackd.2015.06.003.CrossRefGoogle Scholar
Heaf, J. G., Løkkegaard, H. & Madsen, M. (2002) Initial survival advantage of peritoneal dialysis relative to haemodialysis. Nephrology Dialysis Transplantation. doi: 10.1093/ndt/17.1.112.CrossRefGoogle Scholar
Hirsch, J. S. et al. (2020) Acute kidney injury in patients hospitalized with COVID-19. Kidney International 98(1). doi: 10.1016/j.kint.2020.05.006.CrossRefGoogle ScholarPubMed
Hogan, M. C. et al. (2015) Liver involvement in early autosomal-dominant polycystic kidney disease. Clinical Gastroenterology and Hepatology. doi: 10.1016/j.cgh.2014.07.051.CrossRefGoogle Scholar
Kaballo, M. A. et al. (2018) A comparative analysis of survival of patients on dialysis and after kidney transplantation. Clinical Kidney Journal. doi: 10.1093/ckj/sfx117.CrossRefGoogle Scholar
Kajawo, S. et al. (2021) A systematic review of complications associated with percutaneous native kidney biopsies in adults in low- and middle-income countries. Kidney International Reports 6(1), pp. 78–90. doi: 10.1016/j.ekir.2020.10.019.CrossRefGoogle ScholarPubMed
Kamath, N. & Iyengar, A. (2018) Infections and the kidney: a tale from the tropics. Pediatric Nephrology. doi: 10.1007/s00467-017-3785-2.CrossRefGoogle Scholar
Kane, Y., Manga, J. S., Dia, D. G. et al. (2016) Secondary hypertension in Sub-Saharan African populations: a retrospective study between 2011 and 2016 at Regional Hospital of Saint-Louis, Senegal. Open Journal of Nephrology 6, 93–97. doi: 10.4236/ojneph.2016.63012.CrossRefGoogle Scholar
Kellum, J. A. et al. (2012) Kidney disease: improving global outcomes (KDIGO) acute kidney injury work group. KDIGO clinical practice guideline for acute kidney injury. Kidney International Supplements 2(1), 1–138. doi: 10.1038/kisup.2012.1.Google Scholar
Krischock, L., Kennedy, S. E. & Hayen, A. (2017) Multicentre study of treatment outcomes in Australian adolescents and young adults commencing dialysis. Nephrology. doi: 10.1111/nep.12914.CrossRefGoogle Scholar
Legrand, M. et al. (2021) Pathophysiology of COVID-19-associated acute kidney injury. Nature Reviews Nephrology. doi: 10.1038/s41581-021-00452-0.CrossRefGoogle Scholar
Levey, A. S. et al. (2009) A new equation to estimate glomerular filtration rate. Annals of Internal Medicine 150(9), 604–612. doi: 150/9/604 [pii].CrossRefGoogle ScholarPubMed
Levey, A. S., Inker, L. A. & Coresh, J. (2014) GFR estimation: from physiology to public health. American Journal of Kidney Disease. doi: S0272-6386(13)01634-X.Google Scholar
Levin, A. et al. (2024) Executive summary of the KDIGO 2024 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease: known knowns and known unknowns. Kidney International 105(4), 684–701.10.1016/j.kint.2023.10.016CrossRefGoogle Scholar
Lima Verde, F. A. A. et al. (2007) Evaluation of renal function in human visceral leishmaniasis (kala-azar): a prospective study on 50 patients from Brazil. Journal of Nephrology 20(4), 430–436.Google Scholar
Lima Verde, F. A. A. et al. (2009) Renal tubular dysfunction in human visceral leishmaniasis (Kala-azar). Clinical Nephrology. doi: 10.5414/cnp71492.CrossRefGoogle Scholar
Liyanage, T. et al. (2015) Worldwide access to treatment for end-stage kidney disease: a systematic review. Lancet 385(9981), 1975–1982. doi: 10.1016/S0140-6736(14)61601-9.CrossRefGoogle ScholarPubMed
Magee, L. A. et al. (2019) Management of non-severe pregnancy hypertension – A summary of the CHIPS Trial (Control of Hypertension in Pregnancy Study) research publications. Pregnancy Hypertension. doi: 10.1016/j.preghy.2019.08.166.CrossRefGoogle Scholar
Martinez-Rojas, M. A., Vega-Vega, O. & Bobadilla, X. N. A. (2020) Is the kidney a target of SARS-CoV-2? American Journal of Physiology – Renal Physiology. doi: 10.1152/AJPRENAL.00160.2020.CrossRefGoogle Scholar
Maule, S. P. et al. (2020) CKD and pregnancy outcomes in Africa: a narrative review. Kidney International Reports. doi: 10.1016/j.ekir.2020.05.016.CrossRefGoogle Scholar
May, R. M. et al. (2021) A multi-center retrospective cohort study defines the spectrum of kidney pathology in coronavirus 2019 disease (COVID-19). Kidney International. doi: 10.1016/j.kint.2021.07.015.CrossRefGoogle Scholar
Menon, T. et al. (2021) Impact of chronic kidney disease on severity and mortality in COVID-19 patients: a systematic review and meta-analysis. Cureus. doi: 10.7759/cureus.14279.CrossRefGoogle Scholar
Oguejiofor, F. et al. (2021) International Society of Nephrology Global Kidney Health Atlas: structures, organization, and services for the management of kidney failure in Africa. Kidney International Supplements. doi: 10.1016/j.kisu.2021.01.009.CrossRefGoogle Scholar
Ogunlade, O et al. (2018) Jugulometer, a medical device: history, description and uses in non-invasive assessment of jugular venous pressure, cardiology and cardiovascular research. Cardiology and Cardiovascular Research 2(1), 4–7. doi: 10.11648/j.ccr.20180201.12CrossRefGoogle Scholar
Ojji, D. B. et al. (2019) Comparison of dual therapies for lowering blood pressure in black Africans. New England Journal of Medicine. doi: 10.1056/nejmoa1901113.CrossRefGoogle Scholar
Okafor, U. H. (2017) Transplant tourism among kidney transplant patients in Eastern Nigeria. BMC Nephrology. doi: 10.1186/s12882-017-0635-1.CrossRefGoogle Scholar
Okpechi, I. G. et al. (2016) Epidemiology of histologically proven glomerulonephritis in Africa: a systematic review and meta-analysis. PLoS ONE, 11(3). doi: 10.1371/journal.pone.0152203.CrossRefGoogle Scholar
Perazella, M. A. (2018) Pharmacology behind common drug nephrotoxicities. Clinical Journal of the American Society of Nephrology. doi: 10.2215/CJN.00150118.CrossRefGoogle Scholar
Perkovic, V. et al. (2019) Canagliflozin and renal outcomes in type 2 diabetes and nephropathy. New England Journal of Medicine, 380(24), pp. 2295–2306. doi: 10.1056/nejmoa1811744.CrossRefGoogle ScholarPubMed
Ray, D. & Thukral, S. (2017) Microfilariae in the kidney. Tropical Journal of Medical Research. doi: 10.4103/1119-0388.198139.CrossRefGoogle Scholar
Romanowski, K. et al. (2016) Tuberculosis and chronic kidney disease: an emerging global syndemic. Kidney International. doi: 10.1016/j.kint.2016.01.034.CrossRefGoogle Scholar
Sepúlveda, C. et al. (2002) Palliative care: the World Health Organization’s global perspective. Journal of Pain and Symptom Management. doi: 10.1016/S0885-3924(02)00440-2.CrossRefGoogle Scholar
da Silva Junior, G. B. et al. (2017) Kidney involvement in malaria: an update. Revista do Instituto de Medicina Tropical de Sao Paulo. doi: 10.1590/S1678-9946201759053.CrossRefGoogle Scholar
da Silva Junior, G. B., Guardão Barros, E. J. & De Francesco Daher, E. (2014) Kidney involvement in leishmaniasis – a review. Brazilian Journal of Infectious Diseases. doi: 10.1016/j.bjid.2013.11.013.CrossRefGoogle Scholar
Stanifer, J. W. et al. (2015) The epidemiology of chronic kidney disease in Northern Tanzania: a population-based survey. PLoS ONE, 10(4). doi: 10.1371/journal.pone.0124506.CrossRefGoogle ScholarPubMed
Swanepoel, C. R. et al. (2018) Kidney disease in the setting of HIV infection: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference. Kidney International. 10.1016/j.kint.2017.11.007.Google Scholar
Tong, X. & Spradling, P. R. (2015) Increase in nonhepatic diagnoses among persons with hepatitis C hospitalized for any cause, United States, 2004–2011. Journal of Viral Hepatitis. doi: 10.1111/jvh.12414.CrossRefGoogle Scholar
Van der Werf, MJ, de Vlas, SJ, Brooker, S et al. (2003) Quantification of clinical morbidity associated with schistosome infection in sub-Saharan Africa. Acta Tropica 86, 125–139.10.1016/S0001-706X(03)00029-9CrossRefGoogle ScholarPubMed
Van Velthuysen, M. L. F. & Florquin, S. (2000) Glomerulopathy associated with parasitic infections. Clinical Microbiology Reviews. doi: 10.1128/CMR.13.1.55-66.2000.CrossRefGoogle Scholar
Watson, A. R. et al. (2011) Transition from pediatric to adult renal services: a consensus statement by the International Society of Nephrology (ISN) and the International Pediatric Nephrology Association (IPNA). Kidney International. doi: 10.1038/ki.2011.209.CrossRefGoogle Scholar
Wearne, N. et al. (2017) Continuous ambulatory peritoneal dialysis: perspectives on patient selection in low- to middle-income countries. International Journal of Nephrology and Renovascular Disease. doi: 10.2147/IJNRD.S104208.CrossRefGoogle Scholar
Wearne, N. et al. (2020) HIV, drugs and the kidney. Drugs in Context. doi: 10.7573/DIC.2019-11-1.CrossRefGoogle Scholar
WHO (2016) WHO epidemiology adolescent health. www.who.int/maternal_child_adolescent/epidemiology/adolescence/en/.Google Scholar
WHO (2021a) Leishmaniasis, 2021. www.who.int/news-room/fact-sheets/detail/leishmaniasis.Google Scholar
WHO (2021b) Malaria. www.who.int/news-room/fact-sheets/detail/malaria.Google Scholar
WHO (2021c) Schistosomiasis, 2021. www.who.int/schistosomiasis/epidemiology/table/en/.Google Scholar
Yang, C. W., Wu, M. S. & Pan, M. J. (2001) Leptospirosis renal disease. Nephrology Dialysis Transplantation 16(Suppl. 5). doi: 10.1093/ndt/16.suppl_5.73.CrossRefGoogle ScholarPubMed

Bibliography

Adebajo, A, Gabriel, SE (2010). Addressing musculoskeletal health inequity in Africa. Arthritis Care Res (Hoboken); 62: 439–41.10.1002/acr.20032CrossRefGoogle ScholarPubMed
Adebajo, AO, Reid, DM (1991). The pattern of rheumatoid arthritis in West Africa and comparison with a cohort of British patients. Q J Med; 80: 633–40.Google ScholarPubMed
Adelowo, O, Mody, GM, Tikly, M. et al. (2021). Rheumatic diseases in Africa. Nat Rev Rheumatol; 17: 363–74.10.1038/s41584-021-00603-4CrossRefGoogle ScholarPubMed
Agarwal, SS, Phadke, SR, Fredlund, V, Viljoen, D, Beighton, P (1997). Mseleni and Handigodu familial osteoarthropathies: syndromic identity? Am J Med Genetics; 72: 435–9.Google Scholar
American College of Rheumatology guidelines for the initial evaluation of the adult patient with acute musculoskeletal symptoms. Arthritis Rheum; 39: 1–8.Google Scholar
Belachew, DA, Sandu, N, Schaller, B, Guta, Z (2009). Ankylosing spondylitis in sub-Saharan Africa. Postgrad Med J; 85: 353–7.10.1136/pgmj.2007.064717CrossRefGoogle ScholarPubMed
Cassim, B, Mody, GM, Rubin, DL (1990). The prevalence of diffuse idiopathic skeletal hyperostosis in African blacks. Br J Rheumatol; 29: 131–2.10.1093/rheumatology/29.2.131CrossRefGoogle ScholarPubMed
Courtney, P, Doherty, M (2009). Joint aspiration and injection and synovial fluid analysis. Best Pract Res Clin Rheumatol; 23: 161–92.10.1016/j.berh.2009.01.003CrossRefGoogle ScholarPubMed
Daniels, ED, Pettifor, JM, Schnitzler, CM, Russell, SW, Patel, DN (1995). Ethnic differences in bone density in female South Africans. J Bone Miner Res; 10: 359–67.10.1002/jbmr.5650100305CrossRefGoogle Scholar
Erzer et al. (2020) Systemic sclerosis in sub-Saharan Africa: a systematic review. Pan African Medical Journal; 37: 176.Google Scholar
Essouma, M et al. (2020) Systemic lupus erythematosus in native sub-Saharan Africans: a systematic review and meta-analysis. J Autoimmun; 106: 102–348.10.1016/j.jaut.2019.102348CrossRefGoogle ScholarPubMed
Fanouriakis, A, Kostopoulou, M, Alunno, A et al. (2019). 2019 update of the EULAR recommendations for the management of systemic lupus erythematosus. Ann Rheum Dis; 78: 736–45.Google ScholarPubMed
Johansson, H, Dela, SS, Cassim, B et al. (2021). FRAX-based fracture probabilities in South Africa. Arch Osteoporos; 16(1): 51.10.1007/s11657-021-00905-wCrossRefGoogle ScholarPubMed
Maritz, NG, Gerber, AJ, Greyling, SJ, Sandra, BB (2005). A radiological study of the rheumatoid hand in black South Africans. S Afr Med J; 95: 795–7.Google ScholarPubMed
Mathews, CJ, Weston, VC, Jones, A, Field, M, Coakley, G (2010). Bacterial septic arthritis in adults. Lancet; 375: 846–55.10.1016/S0140-6736(09)61595-6CrossRefGoogle ScholarPubMed
McGill, PE (1995). Bacterial infections: pyomyositis. Baillières Clin Rheumatol; 9: 193–200.10.1016/S0950-3579(05)80155-4CrossRefGoogle ScholarPubMed
Mody, GM, Cardiel, MH (2008). Challenges in the management of rheumatoid arthritis in developing countries. Best Pract Res Clin Rheumatol; 22: 621–41.10.1016/j.berh.2008.04.003CrossRefGoogle ScholarPubMed
Njobvu, P, McGill, P, Kerr, H, Jellis, J, Pobee, J (1998) Spondyloarthropathy and human immunodeficiency virus infection in Zambia. J Rheumatol; 25(8): 1553–9.Google ScholarPubMed
Pettifor, JM (2004). Nutritional rickets: deficiency of vitamin D, calcium, or both? Am J Clin Nutr; 80: 1725S–9S.10.1093/ajcn/80.6.1725SCrossRefGoogle ScholarPubMed
Petty, RE, Southwood, TR, Baum, J et al. (1998). Revision of the proposed classification criteria for juvenile idiopathic arthritis: Durban, 1997. J Rheumatol; 25: 1991–4.Google ScholarPubMed
Schneider, M, Manabile, E, Tikly, M (2008). Social aspects of living with rheumatoid arthritis: a qualitative descriptive study in Soweto, South Africa – a low resource context. Hlth Qual Life Outcomes; 6: 54.10.1186/1477-7525-6-54CrossRefGoogle ScholarPubMed
Singwe-Ngandeu, M, Meli, J, Ntsiba, H et al. (2007). Rheumatic diseases in patients attending a clinic at a referral hospital in Yaounde, Cameroon. East Afr Med J; 84: 404–9.Google Scholar
Smolen, JS, Landewé, RBM, Bijlsma, JWJ et al. (2020) EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2019 update. Ann Rheum Dis; 79: 685–99.10.1136/annrheumdis-2019-216655CrossRefGoogle ScholarPubMed
Tikly, M, Navarra, SV (2008). Lupus in the developing world – is it any different? Best Pract Res Clin Rheumatol; 22: 643–55.Google Scholar
Usenbo, A, Kramer, V, Young, T, Musekiwa, A (2015). Prevalence of arthritis in Africa: a systematic review and meta-analysis. PLoS ONE; 10: e0133858.10.1371/journal.pone.0133858CrossRefGoogle Scholar

Bibliography

Arlt, W, Allolio, B (2003). Adrenal insufficiency. Lancet; 361: 1881–93.10.1016/S0140-6736(03)13492-7CrossRefGoogle ScholarPubMed
Baylis, PH, Cheetham, T (1998). Diabetes insipidis. Arch Dis Child; 79: 84–9.10.1136/adc.79.1.84CrossRefGoogle Scholar
Bleichrodt, N, Shrestha, RM, West, CE, Hautvast, JG, van de Vijver, FJ, Born, MP (1996). The benefits of adequate iodine intake. Nutr Rev; 54: S72–8.Google ScholarPubMed
Bornstein, SR, Allolio, B, Arlt, W et al. (2018). Diagnosis and treatment of primary adrenal insufficiency: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab; 101: 364–89.Google Scholar
Food and Drug Administration (2010). FDA Drug Safety Communication: New boxed warning on severe liver injury with propylthiouracil. www.fda.gov/Drugs/DrugSafety/PostmarketDrugSafetyInformationforPatientsandProviders/ucm209023.htm.Google Scholar
Fraser, WD (2009). Hyperparathyroidism. Lancet; 374: 145–58.10.1016/S0140-6736(09)60507-9CrossRefGoogle ScholarPubMed
Hermus, AR, Huysmans, DA (1998). Treatment of benign nodular thyroid disease. N Engl J Med; 338: 1438–47.10.1056/NEJM199805143382007CrossRefGoogle ScholarPubMed
Huddle, KRL (1988). Cardiac dysfunction in primary hypoparathyroidism. S Afr Med J; 73: 242–4.Google ScholarPubMed
Huddle, KRL, Ally, R (1989). Idiopathic hypoparathyroidism in black South Africans. Quart J Med; 70: 53–60.Google ScholarPubMed
Huddle, KRL (2011). Phaeochromocytoma in black South Africans – a 30-year audit. S Afr Med J; 101: 184–8.10.7196/SAMJ.4320CrossRefGoogle ScholarPubMed
Klibanski, A (2010). Prolactinomas. N Engl J Med; 362: 1219–26.10.1056/NEJMcp0912025CrossRefGoogle ScholarPubMed
Lenders, JWM, Eisenhofer, G, Mannelli, M, Pacak, K (2005). Phaeochromocytoma. Lancet; 366: 665–75.10.1016/S0140-6736(05)67139-5CrossRefGoogle ScholarPubMed
Melmed, S (2006). Acromegaly. N Engl J Med; 355: 2558–73.10.1056/NEJMra062453CrossRefGoogle ScholarPubMed
Mofokeng, TRP, Beshyah, SA, Mohamed, F, Ndlovu, KCZ, Ross, IL (2020). Significant barriers to diagnosis and management of adrenal insufficiency in Africa. Endocrine Connect; 5: 445–56.Google Scholar
Nieman, LK Biller, BMK, Findling, JW et al. (2015). Treatment of Cushing’s syndrome: an Endocrine Society clinical practice guideline. JCEM; 100: 2807–31.10.1210/jc.2015-1818CrossRefGoogle ScholarPubMed
Ogbera, AO, Fasanmade, O, Adediran, O (2007). Pattern of thyroid disorders in the southwestern region of Nigeria. Ethn Dis; 17: 327–30.Google ScholarPubMed
Okosieme, OE (2006). Impact of iodination on thyroid pathology in Africa. J Roy Soc Med; 99: 396–401.10.1177/014107680609900816CrossRefGoogle ScholarPubMed
Pearce, EN (2006). Diagnosis and management of thyrotoxicosis. Br Med J; 332: 1369–73.10.1136/bmj.332.7554.1369CrossRefGoogle ScholarPubMed
Pembe, AB, Abeid, MS (2009). Polycystic ovaries and associated clinical and biochemical features among women with infertility in a tertiary hospital in Tanzania. Tanzan J Hlth Res 11: 178–80.Google Scholar
Schneider, HJ, Aimaretti, G, Stalla, IK, Ghigo, E (2007). Hypopituitarism. Lancet; 369: 1461–70.10.1016/S0140-6736(07)60673-4CrossRefGoogle ScholarPubMed
Todd, CH, Allain, T, Gomo, ZAR, Hasler, JA, Ndiweni, M, Oken, E (1995). Increase in thyrotoxicosis associated with iodine supplements in Zimbabwe. Lancet; 346: 1563–4.10.1016/S0140-6736(95)92095-1CrossRefGoogle ScholarPubMed
Todd, CH (1999). Hyperthyroidism and other thyroid disorders – a practical handbook for the recognition and management. WHO/ICCIDD. WHO/NDH/ 99.1.Google Scholar
Todd, CH (2009). Management of thyroid disorders in primary care: challenges and controversies. Postgrad Med J; 85: 655–9.10.1136/pgmj.2008.077701CrossRefGoogle ScholarPubMed
UNICEF (2008). Sustainable elimination of iodine deficiency. Progress since the 1990 World Summit for Children. New York: UNICEF.Google Scholar
Vaidya, B, Pearce, SHS (2008). Management of hypothyroidism in adults. Br Med J; 337: a801.10.1136/bmj.a801CrossRefGoogle ScholarPubMed
WHO, UNICEF, ICCIDD (2007). Assessment of iodine deficiency disorders and monitoring their elimination. A guide for programme managers. 3rd ed. Geneva: WHO.Google Scholar
Williams, TA, Reincke, M (2018) Diagnosis and management of primary aldosteronism: the Endocrine Society guideline 2016 revisited. European Journal of Endocrinology; 179: R19–29.10.1530/EJE-17-0990CrossRefGoogle ScholarPubMed
Young, WF (2007a). Primary aldosteronism. Clin Endocrinol; 66: 607–18.10.1111/j.1365-2265.2007.02775.xCrossRefGoogle ScholarPubMed
Young, WF (2007b). Clinical practice. The incidentally discovered adrenal mass. N Engl J Med; 356: 601–10.10.1056/NEJMcp065470CrossRefGoogle ScholarPubMed
An excellent free on-line resource is ‘The Thyroid Manager’: www.thyroidmanager.org.Google Scholar
‘ICCIDD’ stands for International Council for the Control of Iodine Deficiency Disorders.Google Scholar

References

Adeloye, D, Thompson, JY, Akanbi, MA et al. (2016). The burden of road traffic crashes, injuries, and deaths in Africa: a systematic review and meta-analysis. Bull World Health Organ; 94(7): 510–521. A. doi: 10.2471/BLT.15.163121.CrossRefGoogle Scholar
Ba-Diop, A, Marin, B, Michel Druet-Cabanac, M et al. (2014). Epidemiology, causes, and treatment of epilepsy in sub-Saharan Africa. Lancet Neurol; 13(10): 1029–1044. doi: 10.1016/S1474-4422(14)70114-0.CrossRefGoogle ScholarPubMed
Ballo, R, Viljoen, D, Beighton, P (1994). Duchenne and Becker muscular dystrophy prevalence in South Africa and molecular findings in 128 persons affected. S Afr Med J; 84: 494–497. PMID: 7825085.Google ScholarPubMed
Bateman, KJ, Schinkel, M, Little, F et al. (2007). Incidence of seropositive myasthenia gravis in Cape Town and South Africa. S Afr Med J; (10): 959–962. PMID: 18000579.Google Scholar
Bell, SJ, Koffie, RM, Rattani, A et al. (2019). Global incidence of brain and spinal tumors by geographic region and income level based on cancer registry data. J Clin Neurosci; 66: 121–127.10.1016/j.jocn.2019.05.003CrossRefGoogle ScholarPubMed
Bhigjee, I, Madurai, S, Bill, PL et al. (2001). Spectrum of myelopathies in HIV seropositive South African patients. Neurology; 57: 348–351.10.1212/WNL.57.2.348CrossRefGoogle ScholarPubMed
Cliff, J, Lundquist, P, Martensson, J et al. (1985). Association of high cyanide and low sulphur intake in cassava induced spastic paraparesis. Lancet; 326: 1211–1213.10.1016/S0140-6736(85)90742-1CrossRefGoogle Scholar
Cooper, S, van dr Loeff MS, McConkey S et al. (2009). Neurological morbidity among HTLV – Type 1 infected individuals in a rural West Africa population. J Neurol Neurosurg Psychiatry; 80: 66–68.10.1136/jnnp.2008.152819CrossRefGoogle Scholar
Dekker, MCJ, Suleiman, JM, Bhwana, D et al. (2020). PRKN-related familial Parkinson’s disease: first molecular confirmation from East Africa. Parkinsonism & Related Disoders; 73: 14–15.10.1016/j.parkreldis.2020.02.014CrossRefGoogle ScholarPubMed
Dekker, MCJ, Urasa, SJ, Aerts, MB et al. (2018). Motor neuron disease in sub-Saharan Africa: case series from a Tanzanian referral hospital. J Neurol Neurosurg Psychiatry; 89: 1349–1350.10.1136/jnnp-2017-317858CrossRefGoogle ScholarPubMed
Dewan, MC, Rattani, A, Gupta, S et al. (2018). Estimating the global incidence of traumatic brain injury. J Neurosurg; 1: 1–18.Google Scholar
Donovana, J, Thwaites, GE, Huynha, J. (2020). Tuberculous meningitis: where to from here? Curr Opin Infect Dis; 33: 259–266.10.1097/QCO.0000000000000648CrossRefGoogle Scholar
Dotchin, CL, Walker, RW (2008). The prevalence of essential tremor in rural northern Tanzania. J Neurol Neurosurg Psychiatry; 79(10): 1107–1109.10.1136/jnnp.2007.134304CrossRefGoogle ScholarPubMed
Dotchin, C, Msuya, O, Kissima, J et al. (2008). The prevalence of Parkinson’s disease in rural Tanzania. Mov Disord; 23: 1567–1672.CrossRefGoogle ScholarPubMed
Fisher, RS, Cross, H, French, JA et al. (2017). Operational classification of seizure types by the International League Against Epilepsy: Position Paper of the ILAE Commission for Classification and Terminology. Epilepsia; 58(4): 522–530, doi: 10.1111/epi.13670.CrossRefGoogle Scholar
GBD 2016 Headache Collaborators (2018). Global, regional, and national burden of migraine and tension-type headache, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet Neurol; 17: 954–976.Google Scholar
GBD 2016 Meningitis Collaborators (2018). Global, regional, and national burden of meningitis, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet Neurol; 17: 1061–1082.Google Scholar
Getahun, H, Mekonnen, A, Tekle-Haimanot, R et al. (1999). Epidemic of neurolathyrism in Ethiopia. Lancet; 354: 306–307.10.1016/S0140-6736(99)02532-5CrossRefGoogle ScholarPubMed
Guerchet, M, Mbelesso, P, Ndamba-Bandzouzi, B et al. (2014). Epidemiology of dementia in Central Africa (EPIDEMCA): protocol for a multicentre population-based study in rural and urban areas of the Central African Republic and the Republic of Congo. Springerplus; 3(1): 338. doi: 10.1186/2193-1801-3-338.CrossRefGoogle Scholar
Habib, AG, Yakasai, AM, Owolabi, LF et al. (2013). Neurocognitive impairment in HIV-1-infected adults in Sub-Saharan Africa: a systematic review and meta-analysis. Int J Infect Dis; 17: e820–e831. doi: 10.1016/j.ijid.2013.06.011.CrossRefGoogle ScholarPubMed
Howlett, WP (2018). The role of LP in NDs where there is no neuroimaging. J Neurol Sci; 15(393): 110–112. doi: 10.1016/j.jns.2018.08.005.CrossRefGoogle Scholar
Howlett, WP (2019). Neurological disorders in HIV in Africa: a review. Afri Health Sci; 19(2): 1953–1977.10.4314/ahs.v19i2.19CrossRefGoogle ScholarPubMed
Howlett, WP, Nkya, WM, Mmuni, KA, Missalek, WR (1989). Neurological disorders in AIDS and HIV disease in the northern zone of Tanzania. AIDS; 3: 289–96.10.1097/00002030-198905000-00007CrossRefGoogle ScholarPubMed
Howlett, WP, Brubaker, GR, Mlingi, N et al. (1990). Konzo, an epidemic upper motor neuron disease studied in Tanzania. Brain; 113: 223–235.10.1093/brain/113.1.223CrossRefGoogle ScholarPubMed
Howlett, WP, Vedeler, CA, Nyland, H et al. (1996). Guillain–Barré syndrome in northern Tanzania: a comparison of epidemiological and clinical findings with western Norway. Acta Neurol Scand; 93(1): 44–49.10.1111/j.1600-0404.1996.tb00169.xCrossRefGoogle ScholarPubMed
Joseph, C, Delcarme, A, Vlok, I et al. (2015). Incidence and aetiology of traumatic spinal cord injury in Cape Town, South Africa: a prospective, population-based study. Spinal Cord; 53: 692–696.10.1038/sc.2015.51CrossRefGoogle ScholarPubMed
Kaddumukasa, M, Mugenyi, L, Kaddumukasa, MN et al. (2016). Prevalence and incidence of neurological disorders among adult Ugandans in rural and urban Mukono district; a cross-sectional study. BMC Neurology 16: 227. doi: 10.1186/s12883-016–0732-y.CrossRefGoogle Scholar
Kalaria, RN, Maestre, GE, Arizaga, R et al. (2008). Alzheimer’s disease and vascular dementia in developing countries: prevalence, management, and risk factors. Lancet Neurol; 7(9): 812–826.10.1016/S1474-4422(08)70169-8CrossRefGoogle ScholarPubMed
Kennedy, PGE, Rodgers, J (2019). Clinical and neuropathogenetic aspects of human African trypanosomiasis. Front. Immunol; 10: 39. doi: 10.3389/fimmu.2019.00039.CrossRefGoogle ScholarPubMed
Laizer, S, Kilonzo, K, Urasa, S et al. (2019). Neurological disorders in a consultant hospital in Northern Tanzania. A cohort study. eNeurological Sci; 14: 101–105.Google Scholar
Lekoubou, A, Echouffo-Tcheugui, JB, Kengne, AP (2014). Epidemiology of neurodegenerative diseases in sub-Saharan Africa: a systematic review. BMC Public Health; 14: 653. doi: 10.1186/1471-2458-14-653.CrossRefGoogle ScholarPubMed
Madhusudanan, M, Menon, M, Ummer, K et al. (2008). Clinical and etiological profile of tropical ataxic neuropathy in Kerala, South India. Eur Neurol; 60: 21–26.10.1159/000127975CrossRefGoogle ScholarPubMed
Makene, WJ, Wilson, J (1972). Biochemical studies in Tanzanian patients with ataxic tropical neuropathy. J Nerol Neurosurg Psychiatry; 35: 31–33.10.1136/jnnp.35.1.31CrossRefGoogle ScholarPubMed
Mallewa, M, Vallely, P, Faragher, B et al. (2013). Viral CNS infections in children from a malaria-endemic area of Malawi: a prospective cohort study. Lancet Glob Health; 1: e153–60.10.1016/S2214-109X(13)70060-3CrossRefGoogle ScholarPubMed
Marks, M, Jarvis, JN, Howlett, W et al. (2017). Neurosyphilis in Africa: a systematic review. PLoS Negl Trop Dis; 11(8): e0005880. doi.org/10.1371/journal.pntd.0005880.CrossRefGoogle ScholarPubMed
Mbewe, E, Zairemthiama, P, Yeh, H-H et al. (2015). The epidemiology of primary headache disorders in Zambia: a population-based door-to-door survey. J Headache Pain; 16: 30. doi: 10.1186/s10194-015-0515-7.Google ScholarPubMed
Mboera, LEG, Kishamawe, C, Kimario, E et al. (2019). mortality patterns of toxoplasmosis and its comorbidities in Tanzania: a 10-year retrospective hospital-based survey. Front Public Health; 7: 25. doi: 10.3389/fpubh.2019.00025.CrossRefGoogle ScholarPubMed
Mochan, A, Anderson, D, Modi, G (2016). CIDP in a HIV endemic population: a prospective case series from Johannesburg. South Africa J Neurol Sci; 363: 39–42.10.1016/j.jns.2015.11.013CrossRefGoogle Scholar
Modi, G, Ranchhod, J, Hari, K et al (2011). Non-traumatic myelopathy at the Chris Hani Baragwaneth Hospital, South Africa – the influence of HIV. QJM; 104: 697–703.10.1093/qjmed/hcr038CrossRefGoogle Scholar
Moodley, K, Bill, PLA, Bhigjee, AI et al. (2019). A comparative study of motor neuron disease in HIV-infected and HIV-uninfected patients. J Neurol Sci; 397: 96–102.10.1016/j.jns.2018.12.030CrossRefGoogle ScholarPubMed
Musubire, AK, Meya, DB, Bohjanen, PR et al. (2017). A systematic review of non-traumatic spinal cord injuries in sub-Saharan Africa and a proposed diagnostic algorithm for resource-limited settings. Front Neurol; 8: 618. doi: 10.3389/fneur.2017.00618.CrossRefGoogle Scholar
Oluwole, OS, Onabolu, AO, Link, H et al. (2000). Persistence of tropical ataxic neuropathy in a Nigerian community. J Neurol Neurosurg Psychiatry; 69: 96–101.10.1136/jnnp.69.1.96CrossRefGoogle Scholar
Osuntokun, BO (1968). An ataxic neuropathy in Nigeria: a clinical, biochemical, and electro-physiological study. Brain; 91: 215–248.10.1093/brain/91.2.215CrossRefGoogle Scholar
Paddick S-M, , Longdon, A, Kisoli, A. et al. (2014). The prevalence of dementia sub-types in rural Tanzania. Am J Geriatric Psychiatr; 22(12): 1613–1622.10.1016/j.jagp.2014.02.004CrossRefGoogle Scholar
Paddick, S-M, Longdon, AR, Kisoli, A et al. (2013). Dementia prevalence estimates in sub-Saharan Africa: comparison of two diagnostic criteria. Glob Health Act; 6: 19646. doi.org/10.3402/gha.v6i0.19666:19646.CrossRefGoogle ScholarPubMed
Philip-Ephraim, E, Eyong, K, Chinenye, S et al. (2013). The burden of inpatient neurologic disease in a tropical African hospital. Can J Neurol Sci; 40: 576–579.10.1017/S0317167100014694CrossRefGoogle Scholar
Plant, GT, Mtanda, AT, Arden, GB et al. (1997). An epidemic of optic neuropathy in Tanzania: characterization of the visual disorder and associated peripheral neuropathy. J Neurol Sci; 145: 127–140.10.1016/S0022-510X(96)00162-1CrossRefGoogle ScholarPubMed
Rahimi-Movaghar, V, Sayyah, MK, Akbari H et al. (2013). Epidemiology of traumatic spinal cord injury in developing countries: a systematic review. Neuroepidemiology; 41: 65–85.10.1159/000350710CrossRefGoogle ScholarPubMed
Siddiqi, OK, M, Kapina, R, Kumar et al. (2020). Konzo outbreak in the Western Province of Zambia. Neurology; 94(14): 1495–1501.10.1212/WNL.0000000000009017CrossRefGoogle ScholarPubMed
Tenforde, MW, Gertz, AM, Lawrence, DS et al. (2020). Mortality from HIV-associated meningitis in sub-Saharan Africa: a systematic review and meta-analysis. J Int AIDS Soc; 23(1): e25416.10.1002/jia2.25416CrossRefGoogle ScholarPubMed
Theadom, A, Rodrigues, M, Roxburgh, R et al. (2014). Dystrophies: a systematic literature review. Neuroepidemiology; 43: 259–268. doi.org/10.1159/000369343.CrossRefGoogle ScholarPubMed
Tylleskar, T, Howlett, WP, Aquilonius, SM et al. (1993). Konzo: a distinct disease entity with selective upper motor neuron damage. J Neurol Neurosurg Psychiatry; 56: 638–643.10.1136/jnnp.56.6.638CrossRefGoogle ScholarPubMed
Veltman, JA, Bristow, CC, Klausner, JD (2014). Meningitis in HIV-positive patients in sub-Saharan Africa: a review. J Int AIDS Soc; 10;17(1): 19184. doi: 10.7448/IAS.17.1.19184.CrossRefGoogle ScholarPubMed
Wahlers, K, Menezes, CN, Wong, ML et al. (2012). Cystic echinococcosis in sub-Saharan Africa. Lancet Infect Dis; 12(11): 871–880.10.1016/S1473-3099(12)70155-XCrossRefGoogle ScholarPubMed
Wall, EC, Everett, DB, Mukaka, M et al. (2014). Bacterial meningitis in Malawian adults, adolescents, and children during the era of antiretroviral scale-up and Haemophilus influenzae type b vaccination, 2000–2012. Clin Infect Dis; 58(10): e137–e145.10.1093/cid/ciu057CrossRefGoogle ScholarPubMed
Winkler, AS, Stelzhammer, B, Kerschbaumsteiner, K et al. (2009). The prevalence of headache with emphasis on tension-type headache in rural Tanzania: a community-based study. Cephalalgia; 29: 1317–1325.10.1111/j.1468-2982.2009.01885.xCrossRefGoogle ScholarPubMed
Winkler, AS (2012). Neurocysticercosis in sub-Saharan Africa: a review of prevalence, clinical characteristics, diagnosis, and management. Pathogens Glob Health; 106(5): 261–274.10.1179/2047773212Y.0000000047CrossRefGoogle ScholarPubMed
Woldeamanuel, YW, Andemeskel, AT, Kyei, K et al. (2016). Case fatality of adult tetanus in Africa: Systematic review and meta-analysis. J Neurolog Sci; 368: 292–299.10.1016/j.jns.2016.07.025CrossRefGoogle ScholarPubMed
Woldeamanuel, YW, Andreou, AP, Cowan, RP (2014). Prevalence of migraine headache and its weight on neurological burden in Africa: a 43-year systematic review and meta-analysis of community-based studies. J Neurol Sci; 342(1–2): 1–15. doi: 10.1016/j.jns.2014.04.019.CrossRefGoogle Scholar
Yizengaw, E, Getahun, T, Mulu W et al. (2018). Incidence of human rabies virus exposure in northwestern Amhara, Ethiopia. BMC Infect Dis; 18: 597. doi.org/10.1186/s12879-018-3500-3.CrossRefGoogle ScholarPubMed

References

Bakker, P, Woerdenbach, H, Gooskens, V, Naafs, B, van der Kaaij, R, Wieringa, N (2012). Dermatological preparations for the Tropics Beta Science Shop. University of Groningen, the Netherlands. https://research.rug.nl/en/publications/dermatological-preparations-for-the-tropics-a-formulary-of-dermat.Google Scholar
Dassoni, F, A, Workalemahu, Moronne, A, Naafs, B (2020). Autoimmune skin diseases in Sub Sahara Africa: experience in Ethiopia and South Sudan and review of the prevalence. Community Skin Health; 61(2): 17–24.Google Scholar
Dieng, MT, Ndiaye, D, Ndiaye, AM (1998). Scabies complicated by acute glomerulonephritis in children: 114 cases observed in two years in a pediatric service in Dakar. Dakar Med; 43: 201–4.Google Scholar
Iwuala, C, Taylor, SC (2021). Structural and functional differences in skin of colour. Clin Exp Dermatol. doi: 10.1111/ced.14892.CrossRefGoogle Scholar
Mensah-Quainoo, E, Yeboah-Manu, D, Asebi, C et al. (2008). Diagnosis of Mycobacterium ulcerans infection (Buruli ulcer) at a treatment centre in Ghana: a retrospective analysis of laboratory results of clinically diagnosed cases. Trop Med Int Hlth; 13: 191–8.10.1111/j.1365-3156.2007.01990.xCrossRefGoogle Scholar
Morrone A, Hay R, Naafs B (Eds.). (2020). Skin disorders in migrants. Cham: Springer Nature Switserland AG.10.1007/978-3-030-37476-1CrossRefGoogle Scholar
Mwageni, N, Masenga, JE, Mavura, D, Naafs, B. Management of TEN in developing countries: Care and Clinical skills. http://scitechz.com/dermatology/fulltext/Dermatology-17-1002.pdf.Google Scholar
Naafs, B, Padovese, V (2009). Rural dermatology in the tropics. Clin Dermatol; 27: 252–70.Google Scholar
Naafs, B. (2006). Allergic skin reactions in the tropics. Clin Dermatol; 24: 158–67.Google Scholar
Nienhuis, WA, Stienstra, Y, Thompson, WA et al. (2010). Antimicrobial treatment for early, limited Mycobacterium ulcerans infection: a randomised controlled trial. Lancet; 375: 664–72.10.1016/S0140-6736(09)61962-0CrossRefGoogle ScholarPubMed
Noordhoek, GT, Cockayne, A, Schouls, LM, Meloen, RH, Stolz, E, van Embden, JD (1990). A new attempt to distinguish serologically the subspecies of Treponema pallidum causing syphilis and yaws. J Clin Microbiol; 28: 1600–7.10.1128/jcm.28.7.1600-1607.1990CrossRefGoogle ScholarPubMed
Rampen, F (1980). Melanoma in Africans. Arch Dermatol; 116: 159–60.10.1001/archderm.1980.01640260035006CrossRefGoogle ScholarPubMed
Phillips, R, Sarfo, FS, Guenin-Mace, L et al. (2009). Immunosuppressive signature of cutaneous Mycobacterium ulcerans infection in the peripheral blood of patients with Buruli ulcer disease. J Infect Dis; 200: 1675–84.10.1086/646615CrossRefGoogle ScholarPubMed
Phillips RO, et al. (2020). Rifampicin and clarithromycin (extended release) versus rifampicin and streptomycin for limited Buruli ulcer lesions: a randomised, open-label, non-inferiority phase 3 trial. Lancet; 395(10232):1259–67.Google Scholar
Shibeshi, D (2000). Pattern of skin diseases at the University teaching hospital Addis Ababa, Ethiopia. Int J Dermatol; 39; 822–5.10.1046/j.1365-4362.2000.00085.xCrossRefGoogle ScholarPubMed
Van Hees, CLM, Kunkeler, ACM, Naafs, B (2007). Cutaneous allergies in tropical countries. Expert Rev Dermatol; 2: 639–54.Google Scholar
Van Hees, C, Naafs, B (2014). Common skin diseases in Africa. An illustrated guide. 3rd revised ed. Voorburg: Stichting Troderma. http://africanskindiseases.org/wiki/pdf/skindiseases.pdf.Google Scholar
Burton, M. J., Ramke, J., Marques, A. P. et al. Rapid assessment of avoidable blindness for health service planning. Bulletin of the World Health Organization 2018; 96: 726–728.Google Scholar
Mactaggart, I. , Wallace, S. , Ramke, J. et al. Causes of blindness and vision impairment in 2020. Lancet Global Health 2021; 9: e144–e160.Google Scholar
The Lancet Global Health Commission on Global Eye Health: vision beyond 2020. Lancet Global Health 2021; 9(4): e489–e551.Google Scholar
Vision Loss Expert Group of the Global Burden of Disease Study. World Report on Vision. WHO 2019.Google Scholar

Bibliography

Bright, T, Mulwafu, W, Phiri, M et al. (2019) Diagnostic accuracy of non-specialist versus specialist health workers in diagnosing hearing loss and ear disease in Malawi. Trop Med Int Health; 24(7): 817–828.10.1111/tmi.13238CrossRefGoogle ScholarPubMed
Forsyth, H, Kalumbi, F, Mphaka, E, Tembo, M, Mwenechanya, J, Kayira, K (2004) Hearing loss in Malawian children after bacterial meningitis: incidence and risk factors. Audiologic Med; 2: 100–107.10.1080/16513860410033711CrossRefGoogle Scholar
Irmeli, R, Pelkonen, T, Cruzeiro, ML, Kataja, M, Peltola, H, Pitkaranta, A (2013) Hearing impairment and its predictors in childhood bacterial meningitis in Angola. Pediatric Infectous Disease Journal; 32(5): 563–565.Google Scholar
Maiga, S, Ndiaye, C, Diouf, M et al. (2017) Laryngeal papillomatosis in Senegal: a ten-year experience. Eur Arch Otorhinolaryngol; 135: 221–224.Google Scholar
Monasta, L, Ronfani, L, Marchetti, F, Montico, M, Vecchi Brumatti, L, Bavcar, A (2012) Burden of disease caused by otitis media: systemic review and global estimates. PLoS ONE; 4: e36226.10.1371/journal.pone.0036226CrossRefGoogle Scholar
Mulwafu, W, Kuper, H, Ensink, RJH (2016) Prevalence and causes of hearing impairment in Africa. Trop Med Int Health; 21(2): 158–165.10.1111/tmi.12640CrossRefGoogle ScholarPubMed
Mulwafu, W, Ensink, RJH, Kuper, H, Fagan, J (2017) Survey of ENT services in sub-Saharan Africa: little progress between 2009 and 2015. Global Health Action; 10(1): 1289736.10.1080/16549716.2017.1289736CrossRefGoogle ScholarPubMed
Pascolini, D, Smith, A (2009) Hearing impairment in 2008: A compilation of available epidemiological studies. Int J Audiol; 48: 473–485.10.1080/14992020902803120CrossRefGoogle ScholarPubMed
Sando, Z, Fokouo, J, Mebada, AO, Djoumo, F, Ndjolo, A, Essame Oyono, JL (2016) Epidemiological and histopathological patterns of salivary gland tumors in Cameroon. Pan African Med J; 23; 6. doi:10.11604/pamj.2016.23.66.5105.CrossRefGoogle ScholarPubMed
Stevens, G, Flaxman, S, Brunskill, E, Mascarentas, M, Mathers, CD, Finucane, M (2011) Global and regional hearing impairment prevalence: an analysis of 42 studies in 29 countries. Eur J Publ Health; 23: 146–152.10.1093/eurpub/ckr176CrossRefGoogle ScholarPubMed
WHO (1997) Primary ear and hearing care training resources: advanced level. Geneva www.who.int/pbd/deafness/activities/hearing_care/advanced.pdf?ua=1Google Scholar
Wonkam, A, Noubia, JJ, Djomou, F, Fieggen, K, Njock, R, Bengono Toure, G (2013) Aetiology of childhood hearing in Cameroon. Eur J Med Genet; 56: 20–25.10.1016/j.ejmg.2012.09.010CrossRefGoogle ScholarPubMed

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