from Section 3 - Infection: General Principles
Published online by Cambridge University Press: 18 June 2025
Infection prevention and control (IPC) is defined by the World Health Organization as a practical and evidence-based approach to prevent patients and health workers from harm by avoidable infection and from antimicrobial resistance (WHO 2020a). Historically, IPC concepts emerged from the prevention and management of wound infections, but it has since evolved to approach health-care associated infections (HCAI) across the health system. HCAI are infections that occur in patients receiving care in health facilities, but which were not present or incubating at the time of admission. IPC also encompasses occupational illness as staff working in health settings may acquire HCAI from the workplace. For infection to occur, an infectious agent must leave an individual or reservoir, survive in the environment, and enter a susceptible host. IPC is the art and science of preventing this sequence of events from occurring. Improving IPC in health-care facilities is a mark of quality that encourages workplace safety for patients and health-care workers and safeguards hospitalized patients and their guardians from infectious disease outbreaks.
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