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Chapter 24 - Meningitis

from Section 4 - Major Common Infections

Published online by Cambridge University Press:  18 June 2025

David Mabey
Affiliation:
London School of Hygiene and Tropical Medicine
Martin W. Weber
Affiliation:
World Health Organization
Moffat Nyirenda
Affiliation:
London School of Hygiene and Tropical Medicine
Dorothy Yeboah-Manu
Affiliation:
Noguchi Memorial Institute for Medical Research, University of Ghana
Jackson Orem
Affiliation:
Uganda Cancer Institute, Kampala
Laura Benjamin
Affiliation:
University College London
Michael Marks
Affiliation:
London School of Hygiene and Tropical Medicine
Nicholas A. Feasey
Affiliation:
Liverpool School of Tropical Medicine
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Summary

Meningitis, a clinical syndrome that results from inflammation of the meninges, can be caused by a wide range of organisms – viruses, bacteria, yeasts or helminths and, rarely, it has a non-infectious cause (Table 24.1). Inflammation of the pia and arachnoid membranes results in the leakage of plasma proteins across the blood–brain barrier and the accumulation of inflammatory cells and proteins in the cerebrospinal fluid.

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Publisher: Cambridge University Press
Print publication year: 2025

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References

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