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Chapter 61 - Paragonimiasis

from Section 8 - Helminth Infections

Published online by Cambridge University Press:  18 June 2025

David Mabey
Affiliation:
London School of Hygiene and Tropical Medicine
Martin W. Weber
Affiliation:
World Health Organization
Moffat Nyirenda
Affiliation:
London School of Hygiene and Tropical Medicine
Dorothy Yeboah-Manu
Affiliation:
Noguchi Memorial Institute for Medical Research, University of Ghana
Jackson Orem
Affiliation:
Uganda Cancer Institute, Kampala
Laura Benjamin
Affiliation:
University College London
Michael Marks
Affiliation:
London School of Hygiene and Tropical Medicine
Nicholas A. Feasey
Affiliation:
Liverpool School of Tropical Medicine
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Summary

Paragonimiasis is a food-borne disease caused by lung flukes of the genus Paragonimus. The focus of paragonimiasis on the African continent is in West and Central Africa. Humans acquire the infection by eating raw or undercooked crustaceans. Paragonimiasis most frequently affects the lungs, yet extrapulmonary infection may involve any other organ system. Pulmonary paragonimiasis is characterized by a chronic productive cough, chest pain and haemoptysis. It can easily be mistaken for tuberculosis.

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Publisher: Cambridge University Press
Print publication year: 2025

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References

Appleton, C. C. 2014. Paragonimiasis in KwaZulu-Natal Province, South Africa. J Helminthol, 88, 123–8.10.1017/S0022149X12000831CrossRefGoogle ScholarPubMed
Chai, J. Y. 2013. Paragonimiasis. Handb Clin Neurol, 114, 283–96.10.1016/B978-0-444-53490-3.00023-6CrossRefGoogle ScholarPubMed
Cumberlidge, N., Rollinson, D., Vercruysse, J., Tchuente, Tchuem, Webster, L. A., B. & Clark, P. F. 2018. Paragonimus and paragonimiasis in West and Central Africa: unresolved questions. Parasitology, 145, 1748–57.10.1017/S0031182018001439CrossRefGoogle ScholarPubMed
Rabone, M., Wiethase, J., Clark, P. F., Rollinson, D., Cumberlidge, N. & Emery, A. M. 2021. Endemicity of Paragonimus and paragonimiasis in Sub-Saharan Africa: a systematic review and mapping reveals stability of transmission in endemic foci for a multi-host parasite system. PLoS Negl Trop Dis, 15, e0009120.10.1371/journal.pntd.0009120CrossRefGoogle ScholarPubMed
WHO. 2021. Foodborne parasitic infections: Paragonimiasis (lung fluke).Geneva. www.who.int/publications/i/item/WHO-UCN-NTD-VVE-2021.5.Google Scholar

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