What is persuasion and how does it differ from coercion, indoctrination, and manipulation? Which persuasive strategies are effective, and which contexts are they effective in? The aim of persuasion is attitude change, but when does a persuasive strategy yield a rational change of attitude? When is it permissible to engage in rational persuasion? In this paper, I address these questions, both in general and with reference to particular examples. The overall aims are (i) to sketch an integrated picture of the psychology, epistemology, and ethics of persuasion and (ii) to argue that there is often a tension between the aim we typically have as would-be persuaders, which is bringing about a rational change of mind, and the ethical constraints which partly distinguish persuasion from coercion, indoctrination, and manipulation.