The sensitivity principle in epistemology has faced numerous, considerable, and relentless challenges since it emerged in Nozick’s Philosophical Explanations (1981). In this paper, I develop a version of sensitivity, based on Dretske’s notion of conclusive reasons (1971), that responds to the complaint that sensitivity is either incompatible with or makes an unprincipled mess of higher-level knowledge. There are three key moves in formulating reasons-based Dretskean sensitivity (RDS). First, sensitivity is conceived in terms of reasons, rather than beliefs, that track the truth. Second, focus shifts from whether S would have those reasons in the relevant counterfactual worlds to whether those reasons would be the case. Third, closer attention is paid to the structure of reasons. Critics of Nozick point out that, typically, even when S knows that they do not have a false belief that p, if S were to have a false belief that p, S would nonetheless believe that they do not have a false belief that p, violating Nozickean sensitivity. I explain how this fact does not preclude higher-level knowledge according to RDS, even if the false belief that p were based on their actual method.