Chronological studies are pivotal for understanding different dimensions of the past. Latin America has embraced various archaeometric dating methods, including radiocarbon (14C) dating. This article reviews the development and challenges of radiocarbon databases and datasets in Latin America, analyzing their integration with global projects and highlighting regional disparities. While global databases like IntChron and CARD often marginalize Latin American data, local projects such as ArqueoData, AndesC14, MesoRAD, SAAID and ExPaND focus on regional needs. The fragmentation of radiocarbon data across publications, technical reports, and limited-access archives hinders accessibility and collaboration. This article underscores the necessity of transitioning from static datasets to dynamic web applications, utilizing APIs to enhance data interoperability, incorporating FAIR principles (findability, accessibility, interoperability, and reusability). This article proposes embedding Latin American initiatives within stable, local institutions to ensure sustainability, establishing classification standards for both radiocarbon dates and associated archaeological contexts. Interdisciplinary collaboration between archaeologists and computer scientists is crucial to developing robust, interoperable databases. By embracing these strategies, Latin America can bridge technological and economic gaps, strengthening its contribution to global archaeological research and fostering new insights into the region’s past.