Skip to main content Accessibility help
×
Hostname: page-component-cd9895bd7-7cvxr Total loading time: 0 Render date: 2024-12-27T11:38:17.543Z Has data issue: false hasContentIssue false

3A - Female Age of Menopause Is a Fair Limit for Ovum Donation

For

from Section I - Limits for IVF

Published online by Cambridge University Press:  25 November 2021

Roy Homburg
Affiliation:
Homerton University Hospital, London
Adam H. Balen
Affiliation:
Leeds Centre for Reproductive Medicine
Robert F. Casper
Affiliation:
Mount Sinai Hospital, Toronto
Get access

Summary

Menopause marks the end of female fertility. This can be overcome by assisted reproductive technology to achieve pregnancy at any age by use of ovum donation with IVF and hormone replacement for embryo transfer. However, pregnancy is often hazardous for women over 45, with morbidity and mortality being increased around threefold due to increased risks of all obstetric complications. Risks to the children through prematurity are also significant and may cause lifelong disability or death. In childhood they may experience parental illness or bereavement. National fertility regulators in some countries, individual fertility clinics, and adoption agencies have all set parental age limits. Societal attitudes do not support post-menopausal pregnancy. Young egg donors also have reservations about giving to older recipients. Thus biologically, medically – both from the individual and public health perspectives – and sociologically, female age at menopause is a fair limit for ovum donation.

Type
Chapter
Information
Publisher: Cambridge University Press
Print publication year: 2021

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Heffner, LJ. Advanced maternal age – how old is too old? New Engl J Med. 2004;351:1927–9.CrossRefGoogle ScholarPubMed
Luke, B, Brown, MB. Elevated risks of pregnancy complications and adverse outcomes with increasing maternal age. Hum Reprod. 2007;22(5):1264–72.CrossRefGoogle ScholarPubMed
Knight, M, Bunch, K, Tuffnell, D, et al. (eds.) on behalf of MBRRACE–UK. Saving Lives, Improving Mothers’ Care – Lessons learned to inform maternity care from the UK and Ireland Confidential Enquiries into Maternal Deaths and Morbidity 2015–17. Oxford: National Perinatal Epidemiology Unit, University of Oxford, 2019.Google Scholar
Jeve, YB, Potdar, N, Opoku, A, Khare, M. Donor oocyte conception and pregnancy complications: a systematic review and meta-analysis. BJOG. 2016;123(9):1471–80.CrossRefGoogle ScholarPubMed
RCOG. Multiple pregnancies following assisted conception. Scientific impact paper no. 22. 2018. doi: 10.1111/1471-0528.14974. https://obgyn.onlinelibrary.wiley.com/doi/full/10.1111/1471-0528.14974.Google Scholar

Save book to Kindle

To save this book to your Kindle, first ensure no-reply@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×