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11 - Disrupted Circadian Rhythms, Time Restricted Feeding, and Blood Pressure Regulation

Published online by Cambridge University Press:  07 October 2023

By
Zhenheng Guo ,
Tianfei Hou  and
Ming C. Gong
Edited by
Laura K. Fonken  and
Randy J. Nelson
Laura K. Fonken
Affiliation:
University of Texas, Austin
Randy J. Nelson
Affiliation:
West Virginia University
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Summary

Typical blood pressure (BP) manifests a circadian rhythm, which is often disrupted in hypertension, type 2 diabetes mellitus, kidney disease, and sleep apnea. Disrupted circadian rhythm of BP is emerging as an index for detrimental cardiovascular outcomes. Time-restricted feeding or eating (TRF or TRE) involves restraining the daily food intake time window to 4–12 hours, mostly during the active phase. In addition to the well-documented numerous metabolic benefits of active phase-TRF, emerging evidence indicates profound effects of active phase-TRF on BP circadian rhythm. This chapter reviews the evidence and the underlying mechanisms via which the timing of food intake profoundly affects BP circadian rhythm and briefly discusses the potential of active phase-TRF as a novel behavioral intervention to reduce cardiometabolic risk.

Keywords

time restricted eatingcircadian systemcardiometabolic riskhypertension
Type
Chapter
Information
Biological Implications of Circadian Disruption
A Modern Health Challenge
 , pp. 238 - 255
Publisher: Cambridge University Press
Print publication year: 2023

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