Skip to main content Accessibility help
×
Hostname: page-component-78c5997874-dh8gc Total loading time: 0 Render date: 2024-11-10T11:01:29.088Z Has data issue: false hasContentIssue false

29 - Carbon dioxide pathophysiology

from 1 - Ventilation

Published online by Cambridge University Press:  05 August 2011

J. S. Gravenstein
Affiliation:
University of Florida
Michael B. Jaffe
Affiliation:
Philip Healthcare
Nikolaus Gravenstein
Affiliation:
University of Florida
David A. Paulus
Affiliation:
University of Florida
Get access

Summary

This chapter discusses the reduced and increased CO2 pressures and outlines some of the pathophysiology of CO2 production and transport, with special reference to capnography. Capnography has a special use in the assessment of patients for brain death with regard to the apnea test, wherein measurement of CO2 tensions are a component of assessing the viability of the brainstem. Any disruption in normal mitochondrial function manifests as diminished energy reserves and CO2 production, and is most rapidly evident in organs with high-energy requirements such as the brain, heart, kidney, and, especially, the eye. Carbonic anhydrase comprises a family name for a group of zinc-dependent enzymes that catalyze the reaction of bicarbonate and a proton to form water and CO2. Sodium bicarbonate is sometimes intravenously injected to treat acidemia in patients suffering from metabolic acidosis.
Type
Chapter
Information
Capnography , pp. 283 - 294
Publisher: Cambridge University Press
Print publication year: 2011

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

Save book to Kindle

To save this book to your Kindle, first ensure coreplatform@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×