Book contents
- Case Studies in Dementia
- Case Studies in Dementia
- Copyright page
- Contents
- Contributors
- Preface
- Acknowledgments
- Introduction to the diagnosis of dementia
- Case 1 Subjective cognitive complaint
- Case 2 Man with subjective complaints but abnormal CSF
- Case 3 When mild cognitive impairment really is Alzheimer's disease
- Case 4 Lost for words
- Case 5 Woman with right-sided numbness
- Case 6 Don't be fooled by a misleadingly high MMSE score
- Case 7 Hemiparesis followed by dementia
- Case 8 Young man with behavioral symptoms
- Case 9 Woman with visual complaints
- Case 10 Difficulty playing tennis
- Case 11 Progressive aphasia complicated by intracerebral bleeding
- Case 12 Progressive difficulty with naming and object identification
- Case 13 A lady with weakness, fasciculations, and failing memory
- Case 14 Progressive difficulty producing speech
- Case 15 Young man with progressive speech impairment and weakness
- Case 16 Personality disintegration – it runs in the family
- Case 17 Woman with complaints about her left arm
- Case 18 The aged brain: when the pieces don't fit
- Case 19 Hypersexuality in a 69-year-old man
- Case 20 Man with fluctuating confusion
- Case 21 Man with post-operative cognitive impairment
- Case 22 Penicillin for dementia in a young man
- Case 23 Thiamine for dementia in a young woman
- Case 24 Dizziness in someone with HIV
- Case 25 Case of young man smoking pot but with a mother who died of dementia
- Case 26 University educated man with childish behavior
- Case 27 Frontotemporal lobar dementia vs. solvent intoxication: A piece that does not fit the puzzle
- Case 28 Man with difficulty keeping pace
- Case 29 Young woman with abnormal movements but no family history
- Case 30 Elderly lady with right-sided visual hallucinations
- Case 31 Woman with gait impairment and difficulty reading
- Case 32 Man with problems with reading and calculating
- Case 33 Man with gait impairment and urine incontinence
- Case 34 Falling before forgetting
- Case 35 Man who stopped drinking
- Case 36 Woman with dementia and hepatic disease
- Case 37 Young woman with recurrent “stroke” attacks
- Case 38 Young man with slow cognitive decline
- Case 39 Young woman with lateralized motor symptoms
- Index
Case 14 - Progressive difficulty producing speech
Published online by Cambridge University Press: 16 May 2011
Book contents
- Case Studies in Dementia
- Case Studies in Dementia
- Copyright page
- Contents
- Contributors
- Preface
- Acknowledgments
- Introduction to the diagnosis of dementia
- Case 1 Subjective cognitive complaint
- Case 2 Man with subjective complaints but abnormal CSF
- Case 3 When mild cognitive impairment really is Alzheimer's disease
- Case 4 Lost for words
- Case 5 Woman with right-sided numbness
- Case 6 Don't be fooled by a misleadingly high MMSE score
- Case 7 Hemiparesis followed by dementia
- Case 8 Young man with behavioral symptoms
- Case 9 Woman with visual complaints
- Case 10 Difficulty playing tennis
- Case 11 Progressive aphasia complicated by intracerebral bleeding
- Case 12 Progressive difficulty with naming and object identification
- Case 13 A lady with weakness, fasciculations, and failing memory
- Case 14 Progressive difficulty producing speech
- Case 15 Young man with progressive speech impairment and weakness
- Case 16 Personality disintegration – it runs in the family
- Case 17 Woman with complaints about her left arm
- Case 18 The aged brain: when the pieces don't fit
- Case 19 Hypersexuality in a 69-year-old man
- Case 20 Man with fluctuating confusion
- Case 21 Man with post-operative cognitive impairment
- Case 22 Penicillin for dementia in a young man
- Case 23 Thiamine for dementia in a young woman
- Case 24 Dizziness in someone with HIV
- Case 25 Case of young man smoking pot but with a mother who died of dementia
- Case 26 University educated man with childish behavior
- Case 27 Frontotemporal lobar dementia vs. solvent intoxication: A piece that does not fit the puzzle
- Case 28 Man with difficulty keeping pace
- Case 29 Young woman with abnormal movements but no family history
- Case 30 Elderly lady with right-sided visual hallucinations
- Case 31 Woman with gait impairment and difficulty reading
- Case 32 Man with problems with reading and calculating
- Case 33 Man with gait impairment and urine incontinence
- Case 34 Falling before forgetting
- Case 35 Man who stopped drinking
- Case 36 Woman with dementia and hepatic disease
- Case 37 Young woman with recurrent “stroke” attacks
- Case 38 Young man with slow cognitive decline
- Case 39 Young woman with lateralized motor symptoms
- Index
Summary
This chapter talks about an 83-year-old man with a 3-4-year history of progressive speech difficulty. Past medical history was remarkable for hypertension and ischemic heart disease. Psychiatric history was unremarkable. General neurological exam was remarkable for bilateral cogwheeling in the upper extremities, rigid posture, and bilateral decreased arm swing. Magnetic Resonance Imaging (MRI) of the brain showed diffuse atrophy. Single-Photon Emission Computed Tomography (SPECT) showed decreased perfusion in the left temporo-parietal region. The findings suggested a diagnosis of progressive non-fluent aphasia (PNFA). The possibility of corticobasal syndrome (CBS) was also raised. A variety of neuropathological changes have been associated with PNFA. The most common are non-Alzheimer tauopathies. Alzheimer pathology has also being identified in PNFA, with some reports showing these in up to 30% of cases. In these patients, the distribution of AD pathology may be unusual, showing a frontotemporal pattern.
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- Information
- Case Studies in DementiaCommon and Uncommon Presentations, pp. 98 - 104Publisher: Cambridge University PressPrint publication year: 2011