Darth Vaper strikes again

doi:10.1017/9781108623872.010

Case 10: - Darth Vaper strikes again

Published online by Cambridge University Press: 03 April 2024

Sutanaya Pal and

Daniel Jackson

Edited by

Nevena V. Radonjić ,

Thomas L. Schwartz and

Stephen M. Stahl

Show author details

Nevena V. Radonjić: Affiliation:
State University of New York Upstate Medical University
Thomas L. Schwartz: Affiliation:
State University of New York Upstate Medical University
Stephen M. Stahl: Affiliation:
University of California, San Diego

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Summary

Which is part of the criteria for treatment-resistant schizophrenia (TRS)?

Keywords

schizophrenia treatment-resistant psychosis smoking electronic nicotine delivery system vaping CYP1D2 clozapine (Clozaril)paliperidone (Invega Sustenna)risperidone (Risperdal)olanzapine (Zyprexa)aripiprazole (Abilify)haloperidol (Haldol)electronic nicotine delivery system (ENDS)

Type: Chapter
Information: Case Studies: Stahl's Essential Psychopharmacology , pp. 167 - 182

DOI: https://doi.org/10.1017/9781108623872.010 [Opens in a new window]

Publisher: Cambridge University Press

Print publication year: 2024

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References

Asenjo Lobos, C, Komossa, K, Rummel-Kluge, C, et al. Clozapine versus other atypical antipsychotics for schizophrenia. Cochrane Database Syst Rev 2010; CD006633CrossRef Google Scholar

Bozzatello, P, Bellino, S, Rocca, P. Predictive factors of treatment resistance in first episode of psychosis: a systematic review. Front Psychiatry 2019; 10:67CrossRef Google Scholar PubMed

Demjaha, A, Lappin, JM, Stahl, D, et al. Antipsychotic treatment resistance in first-episode psychosis: prevalence, subtypes and predictors. Psychol Med 2017; 47:1981–9CrossRef Google Scholar PubMed

Gillespie, AL, Samanaite, R, Mill, J, et al. Is treatment-resistant schizophrenia categorically distinct from treatment-responsive schizophrenia? A systematic review. BMC Psychiatry 2017; 17:12CrossRef Google Scholar PubMed

Glasser, AM, Collins, L, Pearson, JL, et al. Overview of Electronic Nicotine Delivery Systems: a systematic review. Am J Prev Med 2017; 52:e33–e66CrossRef Google Scholar PubMed

Granfors, MT, Backman, JT, Laitila, J, et al. Oral contraceptives containing ethinylestradiol and gestodene markedly increase plasma concentrations and effects of tizanidine by inhibiting cytochrome P450 1A2. Clin Pharmacol Ther 2005; 78:400–11CrossRef Google Scholar PubMed

Grover, S, Sahoo, S, Rabha, A, et al. ECT in schizophrenia: a review of the evidence. Acta Neuropsychiatr 2019; 31:115–27CrossRef Google Scholar PubMed

Howes, OD, McCutcheon, R, Agid, O, et al. Treatment-resistant schizophrenia: Treatment Response and Resistance in Psychosis (TRRIP) Working Group consensus guidelines on diagnosis and terminology. Am J Psychiatry 2017; 174:216–29CrossRef Google Scholar

Huhn, M, Nikolakopoulou, A, Schneider-Thoma, J, et al. Comparative efficacy and tolerability of 32 oral antipsychotics for the acute treatment of adults with multi-episode schizophrenia: a systematic review and network meta-analysis. Focus (Am Psychiatr Publ) 2020; 18:443–55Google Scholar PubMed

Kane, J, Honigfeld, G, Singer, J, et al. Clozapine for the treatment-resistant schizophrenic: a double-blind comparison with chlorpromazine. Arch Gen Psychiatry 1988; 45:789–96CrossRef Google Scholar PubMed

Keepers, GA, Fochtmann, LJ, Anzia, JM, et al. The American Psychiatric Association practice guideline for the treatment of patients with schizophrenia. Am J Psychiatry 2020; 177:868–72CrossRef Google Scholar PubMed

Lally, J, Ajnakina, O, Di Forti, M, et al. Two distinct patterns of treatment resistance: clinical predictors of treatment resistance in first-episode schizophrenia spectrum psychoses. Psychol Med 2016; 46:3231–40CrossRef Google Scholar PubMed

Marder, SR, Yang, YS. Clozapine. In Schatzberg, AF, Nemeroff, CB, eds. The American Psychiatric Association Publishing Textbook of Psychopharmacology. Arlington, VA: American Psychiatric Publishing, Inc. 2017.Google Scholar

McEvoy, JP, Lieberman, JA, Stroup, TS, et al. Effectiveness of clozapine versus olanzapine, quetiapine, and risperidone in patients with chronic schizophrenia who did not respond to prior atypical antipsychotic treatment. Am J Psychiatry 2006; 163:600–10CrossRef Google Scholar

Meyer, JM, Stahl, SM. The Therapeutic Threshold and the Point of Futility. Cambridge: Cambridge University Press, 2021, 34–59Google Scholar

Meltzer, HY, Alphs, L, Green, AI, et al. Clozapine treatment for suicidality in schizophrenia: International Suicide Prevention Trial (InterSePT). Arch Gen Psychiatry 2003; 60:82–91CrossRef Google Scholar PubMed

Meyer, JM, Stahl, SM. The Clozapine Handbook: Stahl’s Handbooks. Cambridge: Cambridge University Press, 2019CrossRef Google Scholar

Prior, TI, Baker, GB. Interactions between the cytochrome P450 system and the second-generation antipsychotics. J Psychiatry Neurosci 2003; 28:99–112Google Scholar PubMed

Saffari, AA, Daher, N, Ruprecht, AA, et al. Particulate metals and organic compounds from electronic and tobacco-containing cigarettes: comparison of emission rates and secondhand exposure. Environ Sci Process Impacts 2014; 16(10):2259–67CrossRef Google Scholar PubMed

Schatzberg, A, Nemeroff, C. The American Psychiatric Association Publishing Textbook of Psychopharmacology, 5. Arlington, VA: American Psychiatric Publishing, Inc., 2017CrossRef Google Scholar

Sinclair, DJM, Zhao, S, Qi, F, et al. Electroconvulsive therapy for treatment-resistant schizophrenia. Schizophr Bull 2019; 45:730–2CrossRef Google Scholar PubMed

Singh, H, Dubin, WR, Kaur, S. Drug interactions affecting clozapine levels. J Psychiatr Intensive Care 2015; 11:52–65CrossRef Google Scholar

Smith, T, Mican, L. What to do when your patient who takes clozapine enters a smoke-free facility. Curr Psychiatry 2014; 13:47–8, 57Google Scholar

Stahl, SM. Stahl’s Essential Psychopharmacology: Neuroscientific Basis and Practical Applications, 5. Cambridge: Cambridge University Press, 2021CrossRef Google Scholar

Swainston Harrison, T, Perry, CM. Aripiprazole: a review of its use in schizophrenia and schizoaffective disorder. Drugs 2004; 64:1715–36CrossRef Google Scholar PubMed

Taylor, D, Paton, C, Kapur, S. The Maudsley Prescribing Guidelines in Psychiatry, 11th edn. Chichester: Wiley-Blackwell, 2012Google Scholar

Tiihonen, J, Taipale, H, Mehtälä, J, et al. Association of antipsychotic polypharmacy vs monotherapy with psychiatric rehospitalization among adults with schizophrenia. JAMA Psychiatry 2019; 76:499–507CrossRef Google Scholar PubMed

Tiihonen, J, Vartiainen, H, Hakola, P. Carbamazepine-induced changes in plasma levels of neuroleptics. Pharmacopsychiatry 1995; 28:26–8CrossRef Google Scholar PubMed

Tsuda, Y, Saruwatari, J, Yasui-Furukori, N. Meta-analysis: the effects of smoking on the disposition of two commonly used antipsychotic agents, olanzapine and clozapine. BMJ Open 2014; 4:e004216CrossRef Google Scholar PubMed

Vermeulen, JM, van Rooijen, G, van de Kerkhof, MPJ, et al. Clozapine and long-term mortality risk in patients with schizophrenia: a systematic review and meta-analysis of studies lasting 1.1–12.5 years. Schizophr Bull 2019; 45:315–29CrossRef Google Scholar PubMed

Wagner, E, Löhrs, L, Siskind, D, et al. Clozapine augmentation strategies – a systematic meta-review of available evidence. Treatment options for clozapine resistance. J Psychopharmacol 2019; 33:423–35CrossRef Google Scholar PubMed

Wagner, E, McMahon, L, Falkai, P, et al. Impact of smoking behavior on clozapine blood levels – a systematic review and meta-analysis. Acta Psychiatr Scand 2020; 142:456–66CrossRef Google Scholar

Wang, G, Zheng, W, Li, XB, et al. ECT augmentation of clozapine for clozapine-resistant schizophrenia: a meta-analysis of randomized controlled trials. J Psychiatr Res 2018; 105:23–32CrossRef Google Scholar PubMed

Youn, T, Jeong, SH, Kim, YS, et al. Long-term clinical efficacy of maintenance electroconvulsive therapy in patients with treatment-resistant schizophrenia on clozapine. Psychiatry Res 2019; 273:759–66CrossRef Google Scholar PubMed