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Clinical Case Studies in Long-Term Care Psychiatry Schizophrenia and Long-Acting Injectable Antipsychotics
from Section 3 - Psychotic Disorders
Published online by Cambridge University Press: 31 October 2024
Medication adherence is a major challenge in treating psychiatric conditions, especially conditions that can involve impaired insight and judgement. Conditions requiring strict adherence to antipsychotics may be helped by the use of long-acting injectable medications (LAIs), such as aripiprazole, paliperidone, olanzapine, and risperidone. Long-acting injectible antipsychotics are best started by those with experience in their use but continuing therapy may be managed by primary providers in areas underserved by mental health specialists. Benefits of LAIs include better adherence when compared to oral therapies, the bypassing of potentially unpredictable gastrointestinal pharmacokinetics, and improved steady-state blood levels of medication.
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