from Part 2 - Depression and specific health problems
Published online by Cambridge University Press: 17 September 2009
Introduction
It is estimated that at least 300 million people worldwide are obese and two to three times more are overweight [1]. Rates vary enormously from country to country, but the situation in the USA is particularly alarming: current figures suggest that over 65% of US adults are overweight, of whom over 30% are obese (body mass index [BMI] ≥ 30) and almost 5% are severely obese (BMI ≥ 40) [2]. Although associations between obesity and physical health consequences such as diabetes, heart disease and cancer, as well as all-cause mortality, are well documented [3–6], the psychological impact of obesity remains poorly characterised.
In the heyday of psychosomatics, obesity was believed to be a consequence of either misinterpreting emotional arousal as hunger or using food as a form of self-medication in order to cope with distress [7]. Obese people were assumed to have extensive psychopathology, and the treatment of choice was psychotherapy. However, when larger-scale epidemiological studies were carried out, it became clear that there were no systematic differences in either personality or rates of psychiatric illness between obese and normal-weight adults [8]. With time, the psychosomatic theory lost ground as a basis for management of obesity, but interest in the link with depression has lived on. Recent years have seen evidence that stress is associated with adiposity [9, 10], and both cortisol and leptin have been implicated in linking the hypothalamic-pituitary-adrenocortical (HPA) axis and adipose tissue [11, 12].
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