Skip to main content Accessibility help

We use cookies to distinguish you from other users and to provide you with a better experience on our websites. Close this message to accept cookies or find out how to manage your cookie settings.

Close cookie message
×
Hostname: page-component-cd9895bd7-dk4vv Total loading time: 0 Render date: 2024-12-26T08:40:55.180Z Has data issue: false hasContentIssue false

18 - Integrating clinical with biobehavioural studies of depression and physical illness

from Part 4 - Conclusions

Published online by Cambridge University Press:  17 September 2009

By
Andrew Steptoe
Edited by
Andrew Steptoe
Andrew Steptoe
Affiliation:
Department of Epidemiology and Public Health, University College London, London, UK
Andrew Steptoe
Affiliation:
University College London
Get access

Summary

Depression and health outcomes

The chapters in Part 2 of this book addressed the relationship between depression and specific conditions, including coronary heart disease (CHD), diabetes, cancer, chronic pain and obesity. There is also research linking depression and depressed mood with a number of other health outcomes, including acquired immunodeficiency syndrome (AIDS)-related mortality [1], hospitalisation and death in patients with end-stage renal disease [2], and death among patients with Parkinson's disease [3]. In some of these conditions, depression is associated with worse outcomes, but this is not always the case. As noted in Chapter 10, evidence linking depression with poor outcome in cancer is inconclusive, and Stage et al. [4] have reported in a small study of chronic obstructive pulmonary disease that depressive illness was associated with reduced rather than greater mortality. Some studies have suggested that insulin resistance (a risk factor for CHD and diabetes) is protective against depression [5, 6].

There are two other common chronic conditions in which depression has been studied quite extensively, and these merit fuller discussion since they have not been the subject of separate chapters in this book. The first of these is stroke. Since the pathophysiology of many types of stroke closely resembles that of coronary artery disease, it is perhaps not surprising that associations between depression and future stroke have been identified.

Keywords

cancerchronic paincoronary heart diseasedepressionphysical illnessobesitydiabetes
Type
Chapter
Information
Depression and Physical Illness , pp. 397 - 408
Publisher: Cambridge University Press
Print publication year: 2006

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Cook, J. A., Grey, D., Burke, J., et al., Depressive symptoms and AIDS-related mortality among a multisite cohort of HIV-positive women. Am. J. Public Health 94 (2004), 1133–40.Google Scholar
Lopes, A. A., Bragg, J., Young, E., et al., Depression as a predictor of mortality and hospitalization among hemodialysis patients in the United States and Europe. Kidney Int. 62 (2002), 199–207.Google Scholar
Hughes, T. A., Ross, H. F., Mindham, R. H., Spokes, E. G., Mortality in Parkinson's disease and its association with dementia and depression. Acta Neurol. Scand. 110 (2004), 118–23.Google Scholar
Stage, K. B., Middelboe, T., Pisinger, C., Depression and chronic obstructive pulmonary disease (COPD): impact on survival. Acta Psychiatr. Scand. 111 (2005), 320–3.Google Scholar
Golomb, B. A., Tenkanen, L., Alikoski, T., et al., Insulin sensitivity markers: predictors of accidents and suicides in Helsinki Heart Study screenees. J. Clin. Epidemiol. 55 (2002), 767–73.Google Scholar
Lawlor, D. A., Smith, G. D., Ebrahim, S., Association of insulin resistance with depression: cross sectional findings from the British Women's Heart and Health Study. Br. Med. J. 327 (2003), 1383–4.Google Scholar
Larson, S. L., Owens, P. L., Ford, D., Eaton, W., Depressive disorder, dysthymia, and risk of stroke: thirteen-year follow-up from the Baltimore epidemiologic catchment area study. Stroke 32 (2001), 1979–83.Google Scholar
May, M., McCarron, P., Stansfeld, S., et al., Does psychological distress predict the risk of ischemic stroke and transient ischemic attack? The Caerphilly Study. Stroke 33 (2002), 7–12.Google Scholar
Gump, B. B., Matthews, K. A., Eberly, L. E., Chang, Y. F., Depressive symptoms and mortality in men: results from the Multiple Risk Factor Intervention Trial. Stroke 36 (2005), 98–102.Google Scholar
Wassertheil-Smoller, S., Shumaker, S., Ockene, J., et al., Depression and cardiovascular sequelae in postmenopausal women: the Women's Health Initiative (WHI). Arch. Intern. Med. 164 (2004), 289–98.Google Scholar
Jiang, W., Alexander, J., Christopher, E., et al., Relationship of depression to increased risk of mortality and rehospitalization in patients with congestive heart failure. Arch. Intern. Med. 161 (2001), 1849–56.Google Scholar
Murberg, T. A., Furze, G., Depressive symptoms and mortality in patients with congestive heart failure: a six-year follow-up study. Med. Sci. Monit. 10 (2004), CR643–8.Google Scholar
Junger, J., Schellberg, D., Muller-Tasch, T., et al., Depression increasingly predicts mortality in the course of congestive heart failure. Eur. J. Heart Fail. 7 (2005), 261–7.Google Scholar
Schulz, R., Drayer, R. A., Rollman, B. L., Depression as a risk factor for non-suicide mortality in the elderly. Biol. Psychiatry 52 (2002), 205–25.Google Scholar
Cuijpers, P., Smit, F., Excess mortality in depression: a meta-analysis of community studies. J. Affect. Disord. 72 (2002), 227–36.Google Scholar
Ensinck, K. T., Schuurman, A. G., Akker, M., et al., Is there an increased risk of dying after depression?Am. J. Epidemiol. 156 (2002), 1043–8.Google Scholar
Frojdh, K., Hakansson, A., Karlsson, I., Molarius, A., Deceased, disabled or depressed: a population-based 6-year follow-up study of elderly people with depression. Soc. Psychiatry Psychiatr. Epidemiol. 38 (2003), 557–62.Google Scholar
Wilson, R. S., Bienias, J. L., Leon, C. F. Mendes de, Evans, D. A., Bennett, D. A., Negative affect and mortality in older persons. Am. J. Epidemiol. 158 (2003), 827–35.Google Scholar
Everson-Rose, S. A., House, J. S., Mero, R. P., Depressive symptoms and mortality risk in a national sample: confounding effects of health status. Psychosom. Med. 66 (2004), 823–30.Google Scholar
Steptoe, A., Whitehead, D. L., Depression, stress and coronary heart disease: the need for more complex models. Heart 91 (2005), 419–20.Google Scholar
Dickens, C. M., Percival, C., McGowan, L., et al., The risk factors for depression in first myocardial infarction patients. Psychol. Med. 34 (2004), 1083–92.Google Scholar
Robinson, R. G., Poststroke depression: prevalence, diagnosis, treatment, and disease progression. Biol. Psychiatry 54 (2003), 376–87.Google Scholar
Dong, M., Dube, S. R., Felitti, V. J., Giles, W. H., Anda, R. F., Adverse childhood experiences and self-reported liver disease: new insights into the causal pathway. Arch. Intern. Med. 163 (2003), 1949–56.Google Scholar
Dong, M., Giles, W. H., Felitti, V. J., et al., Insights into causal pathways for ischemic heart disease: adverse childhood experiences study. Circulation 110 (2004), 1761–6.Google Scholar
Friedman, H. S., Booth-Kewley, S., The ‘disease-prone personality’: A meta-analytic view of the construct. Am. Psychol. 42 (1987), 539–55.Google Scholar
Suls, J., Bunde, J., Anger, anxiety, and depression as risk factors for cardiovascular disease: the problems and implications of overlapping affective dispositions. Psychol. Bull. 131 (2005), 260–300.Google Scholar
Friedman, M., Thoresen, C. E., Gill, J. J., et al., Feasibility of altering type A behavior pattern after myocardial infarction: Recurrent Coronary Prevention Project Study – methods, baseline results and preliminary findings. Circulation 66 (1982), 83–92.Google Scholar
Spiegel, D., Bloom, J. R., Kraemer, H. C., Gottheil, E., Effect of psychosocial treatment on survival of patients with metastatic breast cancer. Lancet 2 (1989), 888–91.Google Scholar
Schneiderman, N., Saab, P. G., Catellier, D. J., et al., Psychosocial treatment within sex by ethnicity subgroups in the Enhancing Recovery in Coronary Heart Disease clinical trial. Psychosom. Med. 66 (2004), 475–83.Google Scholar
Herrmann, C., International experiences with the Hospital Anxiety and Depression Scale: a review of validation data and clinical results. J. Psychosom. Res. 42 (1997), 17–41.Google Scholar
Kroenke, K., Spitzer, R. L., Williams, J. B., The PHQ-9: validity of a brief depression severity measure. J. Gen. Intern. Med. 16 (2001), 606–13.Google Scholar
Kroenke, K., Spitzer, R. L., Williams, J. B., The Patient Health Questionnaire-2: validity of a two-item depression screener. Med. Care 41 (2003), 1284–92.Google Scholar
Freedland, K. E., Skala, J. A., Carney, R. M., et al., The Depression Interview and Structured Hamilton (DISH): rationale, development, characteristics, and clinical validity. Psychosom. Med. 64 (2002), 897–905.Google Scholar
Lewis, G., Pelosi, A. J., Araya, R., Dunn, G., Measuring psychiatric disorder in the community: a standardized assessment for use by lay interviewers. Psychol. Med. 22 (1992), 465–86.Google Scholar
Druss, B. G., Bradford, D. W., Rosenheck, R. A., Radford, M. J., Krumholz, H. M., Mental disorders and use of cardiovascular procedures after myocardial infarction. J. Am. Med. Assoc. 283 (2000), 506–11.Google Scholar
Raison, C. L., Miller, A. H., Depression in cancer: new developments regarding diagnosis and treatment. Biol. Psychiatry 54 (2003), 283–94.Google Scholar

Save book to Kindle

To save this book to your Kindle, first ensure no-reply@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×