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Chapter 40 - Diagnosis of Epithelial Ovarian, Fallopian Tubal and Peritoneal Surface Cancers

from Section 9 - Ovary and Fallopian Tubes

Published online by Cambridge University Press:  24 November 2021

By
Céline Montavon Sartorius  and
Viola Heinzelmann-Schwarz
Edited by
Tahir Mahmood ,
Charles Savona-Ventura ,
Ioannis Messinis  and
Sambit Mukhopadhyay
Tahir Mahmood
Affiliation:
Victoria Hospital, Kirkcaldy
Charles Savona-Ventura
Affiliation:
University of Malta, Malta
Ioannis Messinis
Affiliation:
University of Thessaly, Greece
Sambit Mukhopadhyay
Affiliation:
Norfolk & Norwich University Hospital, UK
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Summary

Epithelial ovarian cancers probably derive in the case of the serous histotype from the fimbrial end of the fallopian tube. There is no screening for this disease, which might impact on the overall mortality rate. Therefore, it is crucial to identify patients with higher risk by taking a thorough family history and performing genetic counselling and testing. Diagnostic methods used are tumour marker CA-125, transvaginal ultrasound and CT imaging; however, neither alone nor in combination will these methods detect the disease earlier, even if performed in regular controls. A fixed pelvic mass on bimanual examination is a typical feature for pelvic disease, while extended abdomen and ascites is pathognomonic for peritoneal disease. The prognosis has improved over the years due to more radical debulking in advanced stages and improved adjuvant therapies.

Keywords

cancerepithelialfallopianperitonealrisk factors
Type
Chapter
Information
The EBCOG Postgraduate Textbook of Obstetrics & Gynaecology
Gynaecology
 , pp. 348 - 356
Publisher: Cambridge University Press
Print publication year: 2021

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