Book contents
- The EBCOG Postgraduate Textbook of Obstetrics & Gynaecology
- The EBCOG Postgraduate Textbook of Obstetrics & Gynaecology
- Copyright page
- Dedication
- Contents
- Videos
- Contributors
- Preface
- Section 1 Basic Sciences in Gynaecology
- Section 2 Menstrual Disorders
- Section 3 Reproductive Endocrinology and Infertility
- Section 4 Contraception and STIs
- Section 5 Post-Reproductive Care
- Section 6 Vulva and Vagina
- Section 7 Cervix
- Section 8 Uterus
- Chapter 35 Malignant Disease of Uterine Corpus
- Chapter 36 Uterine Sarcoma and Rare Uterine Malignant Disease
- Section 9 Ovary and Fallopian Tubes
- Section 10 Operative Gynaecology
- Section 11 Public Health Issues in Gynaecology
- Section 12 Miscellaneous
- Index
- Plate Section (PDF Only)
- References
Chapter 35 - Malignant Disease of Uterine Corpus
from Section 8 - Uterus
Published online by Cambridge University Press: 24 November 2021
- The EBCOG Postgraduate Textbook of Obstetrics & Gynaecology
- The EBCOG Postgraduate Textbook of Obstetrics & Gynaecology
- Copyright page
- Dedication
- Contents
- Videos
- Contributors
- Preface
- Section 1 Basic Sciences in Gynaecology
- Section 2 Menstrual Disorders
- Section 3 Reproductive Endocrinology and Infertility
- Section 4 Contraception and STIs
- Section 5 Post-Reproductive Care
- Section 6 Vulva and Vagina
- Section 7 Cervix
- Section 8 Uterus
- Chapter 35 Malignant Disease of Uterine Corpus
- Chapter 36 Uterine Sarcoma and Rare Uterine Malignant Disease
- Section 9 Ovary and Fallopian Tubes
- Section 10 Operative Gynaecology
- Section 11 Public Health Issues in Gynaecology
- Section 12 Miscellaneous
- Index
- Plate Section (PDF Only)
- References
Summary
Malignant disease of uterine corpus is mostly represented by endometrial cancer, the most frequent genital tract neoplasia in developed countries, affecting women more frequently in perimenopause or after menopause.
Classically divided into type I endometrioid tumours (80–90%) and type II tumours, associated with a worse prognosis (e.g. serous, clear cell), it recently became clear that the genomic analysis of these tumours is the most accurate tool to recognize the prognosis of an endometrial neoplasia much earlier.
The diagnosis usually involves a combination of ultrasound and hysteroscopy, and the latter remains the gold standard to obtain an endometrial sample in this setting. The standard treatment and extension of the surgical staging will depend on the pre- and perioperative evaluation, including the histological type and grade, as well as the depth of myometrial invasion. The need for adjuvant therapy is currently decided by the assessment of the risk for recurrence.
- Type
- Chapter
- Information
- The EBCOG Postgraduate Textbook of Obstetrics & GynaecologyGynaecology, pp. 293 - 304Publisher: Cambridge University PressPrint publication year: 2021