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Chapter 21 - Posttraumatic Stress Disorder

An Update on Diagnosis, Etiology, and Treatment

Published online by Cambridge University Press:  02 January 2025

By
John M. Bouras
Edited by
Marsal Sanches  and
Jair C. Soares
Marsal Sanches
Affiliation:
McGovern Medical School, Texas
Jair C. Soares
Affiliation:
McGovern Medical School, Texas
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Summary

This chapter provides a review for post-traumatic stress disorder (PTSD). It starts by presenting the epidemiological data as well as the risk factors in the development of PTSD. It then defines the diagnosis of PTSD, by using both DSM-5 and ICD-11 criteria, and provides a clinical approach on how to clarify differential diagnoses and comorbidities. It then reviews the pathophysiology and pathogenesis of PTSD by looking at neuroanatomic, neuroendocrine, neurochemical, and genetic changes in brain neural networks. It concludes by presenting the current evidence-based options for the treatment and management of PTSD that include psychotherapy and pharmacotherapy.

Keywords

Post-Traumatic Stress DisorderPathophysiologyTraumaAnxiety
Type
Chapter
Information
Fundamentals of Clinical Psychiatry
A Practical Handbook
 , pp. 212 - 220
Publisher: Cambridge University Press
Print publication year: 2025

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References

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