Book contents
- Frontmatter
- Contents
- Acknowledgments
- Introduction
- 1 Clinical Trial Basics
- 2 Actionable Prognostic Biomarkers
- 3 Phase II Designs
- 4 Enrichment Designs
- 5 Including Both Test-Positive and Test-Negative Patients
- 6 Adaptive Threshold Design
- 7 Multiple Predictive Biomarkers
- 8 Prospective–Retrospective Design
- Appendix A Statistics Background
- Appendix B Prognostic Classifiers Based on High-Dimensional Data
- References
- Index
6 - Adaptive Threshold Design
Published online by Cambridge University Press: 05 February 2013
Book contents
- Frontmatter
- Contents
- Acknowledgments
- Introduction
- 1 Clinical Trial Basics
- 2 Actionable Prognostic Biomarkers
- 3 Phase II Designs
- 4 Enrichment Designs
- 5 Including Both Test-Positive and Test-Negative Patients
- 6 Adaptive Threshold Design
- 7 Multiple Predictive Biomarkers
- 8 Prospective–Retrospective Design
- Appendix A Statistics Background
- Appendix B Prognostic Classifiers Based on High-Dimensional Data
- References
- Index
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- Genomic Clinical Trials and Predictive Medicine , pp. 59 - 64Publisher: Cambridge University PressPrint publication year: 2013