from Section 2 - Common Neurologic Presentations: A Symptom-Based Approach
Published online by Cambridge University Press: 10 January 2024
Pain is one of the most common presenting complaints in the emergency department (ED), both acute pain and exacerbation of chronic pain syndromes. Acute pain is accompanied by anxiety and sympathetic hyperactivity, whereas chronic pain is often associated with affective symptoms of depression. Nociceptive (musculoskeletal, inflammatory, or somatic) pain involves activation of the peripheral receptors secondary to tissue damage from trauma or heat. Neuropathic pain involves direct activation of either sensory nerves or ganglia by nerve injury or disease. Differentiation between nociceptive and neuropathic pain in the ED can be difficult, but should be considered for successful management of the pain.
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