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Chapter 6 - Visualization of Ultrasound-Guided Intramuscular Injections in Muscles Relevant for Cervical Dystonia

Published online by Cambridge University Press:  02 November 2023

Daniel Truong
Affiliation:
University of California, Riverside
Dirk Dressler
Affiliation:
Hannover Medical School
Mark Hallett
Affiliation:
National Institutes of Health (NIH)
Christopher Zachary
Affiliation:
University of California, Irvine
Mayank Pathak
Affiliation:
Truong Neuroscience Institute
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Summary

Botulinum toxin injection is a safe and effective procedure, with outcomes improved if selection and targeting of intended muscles is precisely executed. Individual differences in patient anatomy, and in muscle location or size, render the standard landmark-based, blind approach less effective. Also, adjacent structures such as blood vessels, nerves, the lung, or the thyroid gland, may be injured when hit by the cannula. Therefore, image-based guidance is recommended.

Ultrasound is a very safe imaging modality and is superior in image quality and more flexible during the procedure compared to other modalities (fluoroscopy, CT and MRI). Finally, the costs of acquisition and maintenance of a clinical ultrasound system are moderate, compared to other imaging modalities.

In this chapter, we performed selective ultrasound-guided injections using cadaver specimens to illustrate the muscles relevant in the treatment of cervical dystonia. With ultrasound, we advanced the needle using the in-plane technique to the center of each muscle, and performed a selective intramuscular injection using dilute India ink. The specific muscle was then exposed in a standard dissection and the extent of the staining was photo documented. In the last section we present panoramic still images of neck regions with a difficult muscle topology.

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Publisher: Cambridge University Press
Print publication year: 2023

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References

Castagna, A, Albanese, A (2019). Management of cervical dystonia with botulinum neurotoxins and EMG/ultrasound guidance. Neurol Clin Pract, 9(1):6473.Google Scholar
Castelao, M, Marques, RE, Duarte, GS et al. (2017). Botulinum toxin type A therapy for cervical dystonia. Cochrane Database Syst Rev, 12, CD003633.Google ScholarPubMed
Lorentzen, T, Nolsoe, CP, Ewertsen, C et al. (2015). EFSUMB Guidelines on Interventional Ultrasound (INVUS), Part I. General aspects (long version). Ultraschall Med, 36(5), E114.Google ScholarPubMed
Nyhsen, CM, Humphreys, H, Nicolau, C, Mostbeck, G, Claudon, M. (2016). Infection prevention and ultrasound probe decontamination practices in Europe: a survey of the European Society of Radiology. Insights Imaging, 7(6), 841–7.Google Scholar
Schramm, A, Baumer, T, Fietzek, U et al. (2015). Relevance of sonography for botulinum toxin treatment of cervical dystonia: an expert statement. J Neural Transm (Vienna), 122(10), 1457–63.Google ScholarPubMed
Truong, DD, Jost, WH (2006). Botulinum toxin: clinical use. Parkinsonism Relat Disord, 12(6), 331–55.CrossRefGoogle ScholarPubMed

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