Skip to main content Accessibility help

We use cookies to distinguish you from other users and to provide you with a better experience on our websites. Close this message to accept cookies or find out how to manage your cookie settings.

Close cookie message
×
Hostname: page-component-cd9895bd7-dzt6s Total loading time: 0 Render date: 2024-12-28T15:11:10.706Z Has data issue: false hasContentIssue false

Chapter 10 - Methods for Enhancing Surgical Sperm Retrieval Success

from Part II - Sperm Retrieval

Published online by Cambridge University Press:  09 April 2021

By
Jordan A. Cohen  and
Ranjith Ramasamy
Edited by
Ashok Agarwal ,
Ahmad Majzoub  and
Sandro C. Esteves
Ashok Agarwal
Affiliation:
The Cleveland Clinic Foundation, Cleveland, OH, USA
Ahmad Majzoub
Affiliation:
Hamad Medical Corporation, Doha, Qatar
Sandro C. Esteves
Affiliation:
Andrology & Human Reproduction Clinic, Sao Paulo, Brazil
Get access

Summary

Patients with azoospermia were once considered to be infertile, with few treatment options. A number of sperm retrieval methods have been developed to obtain spermatozoa from the epididymis and testicles of azoospermic men. This chapter addresses methods for enhancing surgical sperm retrieval and highlights the techniques, imaging modalities, medical therapies, and additional procedures that have led to this increased success.

Keywords

sperm retrievalmicro-TESEmultiphoton microscopyvaricocele repair
Type
Chapter
Information
Manual of Sperm Retrieval and Preparation in Human Assisted Reproduction , pp. 86 - 89
Publisher: Cambridge University Press
Print publication year: 2021

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Rosenlund, B, Westlander, G, Wood, M, et al. Sperm retrieval and fertilization in repeated percutaneous epididymal sperm aspiration. Hum Reprod Update 1998;13(1O):2805–2807.Google Scholar
Esteves, SC, Lee, W, Benjamin, DJ, et al. Reproductive potential of men with obstructive azoospermia undergoing percutaneous sperm retrieval and intracytoplasmic sperm injection according to the cause of obstruction. J Urology 2013;189(1):232–237.Google Scholar
Coward, R, Mills, J. A step-by-step guide to office-based sperm retrieval for obstructive azoospermia. Transl Androl Urol 2017;6(4):730–744.Google Scholar
Lin, YM, Hsu, CC, Kuo, TC, et al. Percutaneous epididymal sperm aspiration versus microsurgical epididymal sperm aspiration for irreparable obstructive azoospermia: experience with 100 cases. JFMA 2000;99(6):459–465.Google Scholar
Esteves, SC, Miyaoka, R, Orosz, JE, et al. An update on sperm retrieval for azoospermic males. Clinics 2013;68(S1):99–110.Google Scholar
Donoso, P. Which is the best sperm retrieval technique for non-obstructive azoospermia? A systematic review. Hum Reprod Update 2007;13(6):539–549.CrossRefGoogle ScholarPubMed
Ramasamy, R, Yagan, N, Schlegel, PN. Structural and functional changes to the testis after conventional vs. microdissection testicular sperm extraction. Urology 2005;65:1190–1194.Google Scholar
Fraietta, R. Microdissection is the best way to perform sperm retrieval in men with non-obstructive azoospermia. Int Braz J Urol 2018;44(6):1063–1066.Google Scholar
Shin, DH, Turek, PJ. Sperm retrieval techniques. Urol Nat Rev 2013;10:723–730.CrossRefGoogle ScholarPubMed
Shiraishi, K, Ohmi, C, Shimabukuro, T, Matsuyama, H. Human chorionic gonadotropin treatment prior to microdissection testicular sperm extraction in non-obstructive azoospermia. Hum Reprod 2012;27(2):331–339.Google Scholar
Hussein, A, Ozgok, Y, Ross, L, Rao, P, Niederberger, C. Optimization of spermatogenesis-regulating hormones in patients with non-obstructive azoospermia and its impact on sperm retrieval. BJU Int 2013;111(3):110–114.Google Scholar
Ramasamy, R, Sterling, J, Fisher, ES, et al. Identification of spermatogenesis with multiphoton microscopy: an evaluation in a rodent model. J Urol 2011;186:2487–2492.Google Scholar
Ramasamy, R, Sterling, J, Manzoor, M, et al. Full field optical coherence tomography can identify spermatogenesis in a rodent Sertoli-cell only model. J Pathol Inform 2012;3:4.Google Scholar
Ran, R, Kohn, TP, Ramasamy, R. Innovations in surgical management of nonobstructive azoospermia. Indian J Urol 2016;32(1):15–20.Google Scholar
Guercio, C, Patil, D, Mehta, A. Hypogonadism is independently associated with varicocele repair in a contemporary cohort of men in the USA. Asian J Androl 2018;21(1):45–49.Google Scholar
Abdelrahim, F, Mostafa, A, Hamdy, A, et al. Testicular morphology and function in varicocele patients: pre-operative and post-operative histopathology. Br J Urol 1993;72:643–647.Google Scholar
Agarwal, A, Deepinder, F, Cocuzza, M, et al. Efficacy of varicocelectomy in improving semen parameters: new meta-analytical approach. Urology. 2007;70(3):532–538.Google Scholar
Kroese, AC, de Lange, NM, Collins, J, Evers, JL. Surgery or embolization for varicoceles in subfertile men. Cochrane Database Syst Rev 2012;10:CD000479.Google Scholar
Zampieri, N, Bosaro, L, Costantini, C, Zaffagnini, S, Zampieri, G. Relationship between testicular sperm extraction and varicocelectomy in patients with varicocele and nonobstructive azoospermia. Urology 2013;82(1):74–77.Google Scholar

Save book to Kindle

To save this book to your Kindle, first ensure no-reply@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×