Published online by Cambridge University Press: 14 October 2021
Depression is a common mental illness that is receiving increasing clinical, academic and even political attention. The World Health Organization (WHO) stated in its report of 2004 that depression is one of the most significant health challenges of the twenty-first century in terms of its effect on disability and loss of function, and it ranked depression as the third leading cause of burden of disease worldwide, as measured by disease-adjusted life-years. It is the leading cause of disease burden in the Americas, and is projected to be the leading cause of disease burden worldwide by 2030. In addition to being an important condition in its own right, it is increasingly being recognised as a condition that, when comorbid with physical illness, has a significant effect on recovery and even mortality. Comorbid mental disorders with endocrine conditions may present challenges both for the patient and for their healthcare providers. The evidence for effective joint interventions is at an early stage, and individuals with psychiatric disorders often experience inequalities in accessing routine physical healthcare.
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