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Chapter 27 - Sedation for Assisted Reproductive Technologies

Published online by Cambridge University Press:  12 December 2024

Richard D. Urman
Affiliation:
Ohio State University
Alan David Kaye
Affiliation:
Louisiana State University School of Medicine
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Summary

Assisted reproductive technologies (ART) refers to a set of techniques utilizing reproductive cells and/or embryos outside of the body to help patients conceive. These technologies have been made possible by advances in endocrine assays, controlled ovarian stimulation, cryopreservation, ultrasonography, and a range of procedures on oocytes, sperm, and embryos. An ART physician is a gynecologist specially trained in reproductive endocrinology. In vitro fertilization (IVF) is a term used to describe the process of obtaining an oocyte and uniting it with sperm outside of the body, and later transferring the developing embryo into the uterus. The most common method for obtaining oocytes is the transvaginal ultrasound-guided oocyte retrieval. This procedure is also the most painful part of an IVF cycle and therefore requires sedation and analgesia. This chapter focuses on sedation for oocyte retrieval and related ART procedures.

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Chapter
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Publisher: Cambridge University Press
Print publication year: 2024

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References

References

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Additional Reading

Bokhari, A, Pollard, BJ. Anaesthesia for assisted conception. Eur J Anaesthesiol. 1998;15:391–6.CrossRefGoogle ScholarPubMed
Elkington, M, Kehoe, J, Acharya, U. Policy and Practice Committee of the British Fertility Society. Recommendations for good practice for sedation in assisted conception. Hum Fertil (Camb). 2003;6:7780.CrossRefGoogle Scholar
Gan, TJ, Meyer, T, Apfel, CC, et al. Consensus guidelines for managing postoperative nausea and vomiting. Anesth Analg. 2003;97:6271.CrossRefGoogle ScholarPubMed
Kwan, I, Bhattacharya, S, Knox, F, McNeil, A. Conscious sedation and analgesia for oocyte retrieval procedures: a Cochrane review. Hum Reprod 2006;21:1672–9.CrossRefGoogle ScholarPubMed
Kwan, I, Wang, R, Pearce, E, Bhattacharya, S. Pain relief for women undergoing oocyte retrieval for assisted reproduction. Cochrane Database Syst Rev. 2018;5:CD004829.Google ScholarPubMed
Schenker, JG, Ezra, Y. Complications of assisted reproductive techniques. Fertil Steril. 1994;61:411–22.CrossRefGoogle ScholarPubMed
Toledano, RD, Kodali, BS, Camann, WR. Anesthesia drugs in the obstetric and gynecologic practice. Rev Obstet Gynecol. 2009;2:93100.Google ScholarPubMed
Trout, SW, Vallerand, AH, Kemmann, E. Conscious sedation for in vitro fertilization. Fertil Steril. 1998;69:799808.CrossRefGoogle ScholarPubMed
Tsen, LC. From Darwin to desflurane? Anesthesia for assisted reproductive technologies. Anesth Analg. 2002;94 (Suppl):109–14.Google Scholar
Wallach, EE, Zacur, HA. Reproductive Medicine and Surgery. St Louis, MO: Mosby, 1995:849.Google Scholar

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