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Chapter 13 - Trust and Oxytocin

Context-Dependent Exogenous and Endogenous Modulation of Trust

from Part IV - Neuromolecular Level of Trust

Published online by Cambridge University Press:  09 December 2021

By
Zhimin Yan  and
Peter Kirsch
Edited by
Frank Krueger
Frank Krueger
Affiliation:
George Mason University, Virginia
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Summary

The neuropeptide oxytocin (OXT) has been linked to interpersonal trust. While initial behavioral studies demonstrated a facilitating effect of OXT on trusting behavior, more recently these findings have been challenged. In this chapter we review the literature reporting two approaches that are used to evaluate OXT’s effects: exogenous OXT administration and the investigation of the endogenous OXT system. With respect to trust, we report results from studies investigating trusting behavior, mostly using economic games, and studies looking on the intention to trust other individuals. Overall, clear evidence for a direct trust-promoting effect of OXT as proposed by early studies cannot be found. Instead, there is evidence that the relationship between OXT and trust is modulated by manifold contextual factors that are closely interrelated, e.g., social affiliation, personality traits, gender, mental disorders, and genetic disposition. Furthermore, it could be argued that the effect of OXT on trust is not a specific one but only a subphenomenon of the more general prosocial effect of the neuropeptide.

Future research should aim to conceive models of the OXT–trust connection considering the interactions between genes, brain functioning, and the environment, advancing the knowledge of understanding interpersonal trust.

Keywords

oxytocinintranasal applicationendogenous oxytocingenetic variationtrusting behaviorintention to trustprosocial behavior
Type
Chapter
Information
The Neurobiology of Trust , pp. 315 - 337
Publisher: Cambridge University Press
Print publication year: 2021

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