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22 - Can one identify preschizophrenia children?

Published online by Cambridge University Press:  04 August 2010

By
Eugenia Kravariti ,
Paola Dazzan ,
Paul Fearon  and
Robin M. Murray
Edited by
Matcheri S. Keshavan ,
James L. Kennedy  and
Robin M. Murray
Eugenia Kravariti
Affiliation:
Institute of Psychiatry, King's College, London, UK
Paola Dazzan
Affiliation:
Institute of Psychiatry, King's College, London, UK
Paul Fearon
Affiliation:
Institute of Psychiatry, King's College, London, UK
Robin M. Murray
Affiliation:
Institute of Psychiatry, King's College, London, UK
Matcheri S. Keshavan
Affiliation:
University of Pittsburgh
James L. Kennedy
Affiliation:
Clarke Institute of Psychiatry, Toronto
Robin M. Murray
Affiliation:
Institute of Psychiatry, London
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Summary

Childhood antecedents of schizophrenia may variably reflect integral components of the schizophrenia diathesis, non-specific factors that potentiate this predisposition, or early manifestations of the disorder itself. This chapter explores the nature of the childhood antecedents of schizophrenia. It explores whether children who develop schizophrenia in adulthood are distinguishable from control children. The chapter examines how strong the association between the distinguishing features of preschizophrenia children as a group and the later development of the disorder is. It also explains ways we can identify preschizophrenia children on the basis of these characteristics. The early risk factors that flag the preschizophrenia status are also considered. Particular emphasis is on prospective population-based, high-risk, and follow-back studies. The measures investigated by the high-risk paradigm can aid in identification of truly vulnerable individuals within the high-risk population.

Keywords

archival-observational studieschildhood antecedentscontrol childrenschizophreniapreschizophrenia childrenhigh-risk studies
Type
Chapter
Information
Neurodevelopment and Schizophrenia , pp. 415 - 431
Publisher: Cambridge University Press
Print publication year: 2004

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