Skip to main content Accessibility help

We use cookies to distinguish you from other users and to provide you with a better experience on our websites. Close this message to accept cookies or find out how to manage your cookie settings.

Close cookie message
×
Hostname: page-component-cd9895bd7-mkpzs Total loading time: 0 Render date: 2024-12-28T23:25:23.180Z Has data issue: false hasContentIssue false

Chapter 10 - Neurological complications of systemic disorders

Published online by Cambridge University Press:  07 October 2011

By
Brian J. Scott
Edited by
S. Andrew Josephson ,
W. David Freeman  and
David J. Likosky
S. Andrew Josephson
Affiliation:
University of California, San Francisco
W. David Freeman
Affiliation:
Mayo Clinic
David J. Likosky
Affiliation:
Evergreen Hospital Medical Center, Kirkland, WA
Get access

Summary

Neurological symptoms can occur in a multitude of infectious, inflammatory, autoimmune or metabolic disorders. In hospitalized patients, neurological manifestations of systemic disorders may include confusion, depressed level of consciousness or coma, focal neurological deficits, seizures, headaches or meningeal signs. Thyroid disease is present in approximately 1-2% of hospitalized patients. Systemic lupus erythematosis (SLE) is an autoimmune disorder that affects multiple organ systems. Neurological involvement is not a requirement for diagnosis, but the presence of seizures or psychosis without any plausible alternate explanation fulfills one of the 11 American College of Rheumatology (ACR) diagnostic criteria. Hepatic encephalopathy (HE) encompasses a wide range of neurological findings in the context of acute or chronic liver failure. Studies of liver transplant patients show a rate of neurological complications between 20 and 30%, with encephalopathy (11-15%) and seizure (6%) accounting for the majority of events.

Keywords

cerebral bloodflowcerebral vasospasmcerebrovascular diseasessubarachnoid hemorrhageintracerebral hemorrhageCT imaging
Type
Chapter
Information
Neurohospitalist Medicine , pp. 142 - 152
Publisher: Cambridge University Press
Print publication year: 2011

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

Save book to Kindle

To save this book to your Kindle, first ensure no-reply@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×