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Case 20 - Diabetic Neuropathy

from Peripheral Neuropathies

Published online by Cambridge University Press:  29 November 2024

Jessica E. Hoogendijk
Affiliation:
University Medical Center Utrecht
Marianne de Visser
Affiliation:
Amsterdam University Medical Center
Pieter A. van Doorn
Affiliation:
Erasmus MC, University Medical Center, Rotterdam
Erik H. Niks
Affiliation:
Leiden University Medical Center
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Summary

A 76-year-old man was referred with a diagnosis of ‘motor neuron disease’ or ‘polyneuropathy’. For about eight months he had noticed progressive muscle weakness in his right leg associated with pain, initially more intense than at referral, and a numb feeling around the right knee. Two years previously his left hand had become weak and wasted, associated with loss of sensation of the ring finger, the little finger, and the ulnar part of the palm of his hand. He had lost weight (5 kg) unintentionally over the past six months. He had always been very active, but was now no longer able to walk his dog or do some gardening. He was recently diagnosed with diabetes mellitus (DM) for which oral antidiabetics were prescribed. Family history was unremarkable.

Type
Chapter
Information
Neuromuscular Disease
A Case-Based Approach
, pp. 127 - 129
Publisher: Cambridge University Press
Print publication year: 2024

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References

Suggested Reading

Feldman, EL, Callaghan, BC, Pop-Busui, R, et al. Diabetic neuropathy. Nat Rev Dis Primers 2019;5(1):41. doi: 10.1038/s41572-019-0092-1. PMID: 31197153.CrossRefGoogle ScholarPubMed
Izenberg, A, Perkins, BA, Bril, V. Diabetic neuropathies. Semin Neurol 2015;35(4):424430. doi: 10.1055/s-0035-1558972. Epub 2015 Oct 6. PMID: 26502765.Google ScholarPubMed
Ng, PS, Dyck, PJ, Laughlin, RS, et al. Lumbosacral radiculoplexus neuropathy: incidence and the association with diabetes mellitus. Neurology 2019;92(11):e1188e1194. doi: 10.1212/WNL.0000000000007020. Epub 2019 Feb 13. PMID: 30760636; PMCID: PMC6511105.CrossRefGoogle ScholarPubMed

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