Skip to main content Accessibility help
×
Hostname: page-component-cd9895bd7-lnqnp Total loading time: 0 Render date: 2024-12-25T17:07:18.793Z Has data issue: false hasContentIssue false

Case 24 - Drug-Induced Polyneuropathies: Amiodarone Polyneuropathy

from Peripheral Neuropathies

Published online by Cambridge University Press:  29 November 2024

Jessica E. Hoogendijk
Affiliation:
University Medical Center Utrecht
Marianne de Visser
Affiliation:
Amsterdam University Medical Center
Pieter A. van Doorn
Affiliation:
Erasmus MC, University Medical Center, Rotterdam
Erik H. Niks
Affiliation:
Leiden University Medical Center
Get access

Summary

A 76-year-old man complained about progressive dull feelings and weakness of the distal lower limbs that gradually progressed over a couple of months to the proximal legs and the hands. In addition, there was minor myalgia in the proximal muscles. He had had a myocardial infarction with cardiac arrhythmia three years earlier. He was treated with amiodarone afterwards. He did not have visual complaints and was otherwise healthy. He did not drink alcohol or use other drugs. He had not been treated with cytostatic drugs.

Type
Chapter
Information
Neuromuscular Disease
A Case-Based Approach
, pp. 137 - 138
Publisher: Cambridge University Press
Print publication year: 2024

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Suggested Reading

Orr, CF, Ahlskog, JE. Frequency, characteristics, and risk factors for amiodarone neurotoxicity. Arch Neurol 2009;66(7):865869. doi: 10.1001/archneurol.2009.96. PMID: 19597088.CrossRefGoogle ScholarPubMed
Peters, J, Staff, NP. Update on toxic neuropathies. Curr Treat Options Neurol 2022;24(5):203216. doi: 10.1007/s11940-022-00716-5. Epub 2022 Apr 6. PMID: 36186669; PMCID: PMC9518699.CrossRefGoogle ScholarPubMed
Smyth, D, Kramarz, C, Carr, AS, Rossor, AM, Lunn, MP. Toxic neuropathies: a practical approach. Pract Neurol 2023;23(2):120130. doi: 10.1136/pn-2022-003444. Epub 2023 Jan 25. PMID: 36697225.CrossRefGoogle ScholarPubMed
Stähli, BE, Schwab, S. Amiodarone-induced skin hyperpigmentation. QJM 2011;104(8):723724. doi: 10.1093/qjmed/hcq131. Epub 2010 Jul 30. PMID: 20675394.CrossRefGoogle ScholarPubMed
Vassallo, P, Trohman, RG. Prescribing amiodarone: an evidence-based review of clinical indications. JAMA 2007;298(11):13121322. doi: 10.1001/jama.298.11.1312. PMID: 17878423.CrossRefGoogle ScholarPubMed

Save book to Kindle

To save this book to your Kindle, first ensure no-reply@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×