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4 - The Immune System

Innate and Adaptive

Published online by Cambridge University Press:  13 July 2023

Richard B. Tenser
Affiliation:
Professor Emeritus of Pennsylvania State University
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Summary

The innate and the acquired immune systems combat viral infections. The former is infection type independent. The latter is infection type dependent and takes several days to be “educated” as to the, for example, specific viral infection. With that, B and T lymphocytes are activated. B lymphocytes make specific antibody, which is readily measured, while T lymphocyte functions are not so easily measured.

Specific antibody is measured to indicate that a specific infection has occurred. Antibody (monoclonal or polyclonal) may also be used to treat individuals. Such antibody-treated individuals are passively immunized, which is short lasting as compared with more long-lasting active immunity. The latter is achieved by recovery from infection or vaccine immunization.

Immunization with vaccines has been very important in public health. New types of vaccines have been developed, with recent emphasis particularly on mRNA vaccines. These can be made much more quickly than prior types of vaccines. They target a specific viral protein (antigen) and may find use in other types of illnesses where a specific abnormal protein is identified.

While side effects may occur with vaccines, as is the case with all medications, they are very safe.

Type
Chapter
Information
Neurovirology
Measuring, Interpreting, and Understanding Viruses
, pp. 68 - 93
Publisher: Cambridge University Press
Print publication year: 2023

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References

Further Reading

Abbas, AK, Lichtman, AH, Pillai, S. Cellular and Molecular Immunology, 10th ed. Elsevier Health Sciences, 2017Google Scholar
Bagnoli, F, Rappuoli, R. Advanced Vaccine Research: Methods for the Decade of Vaccines, Caister Academic Press, 2015. Book 978–1–91090–03–6 E-book 978–1–91090–04–3Google Scholar

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  • The Immune System
  • Richard B. Tenser, Professor Emeritus of Pennsylvania State University
  • Book: Neurovirology
  • Online publication: 13 July 2023
  • Chapter DOI: https://doi.org/10.1017/9781009235563.005
Available formats
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  • The Immune System
  • Richard B. Tenser, Professor Emeritus of Pennsylvania State University
  • Book: Neurovirology
  • Online publication: 13 July 2023
  • Chapter DOI: https://doi.org/10.1017/9781009235563.005
Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

  • The Immune System
  • Richard B. Tenser, Professor Emeritus of Pennsylvania State University
  • Book: Neurovirology
  • Online publication: 13 July 2023
  • Chapter DOI: https://doi.org/10.1017/9781009235563.005
Available formats
×