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Chapter 12 - Opioid Effect and Acute Pain

Published online by Cambridge University Press:  14 November 2024

Merlin D. Larson
Merlin D. Larson
Affiliation:
University of California, San Francisco
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Summary

The fact that opioids constrict the pupil is known to healthcare workers and the lay public. In this chapter, the mechanism of this effect is discussed and how an understanding of this mechanism can be useful to the clinician. There are many parameters that can be measured from the pupil with portable pupillometers. The measure that most closely predicts the onset of severe respiratory depression is pupillary unrest in ambient light (PUAL). This measure is compared to pupil size and pupillary constriction amplitude as a measure of toxic levels of opioids.

Keywords

OpioidsPupilInhibition
Type
Chapter
Information
A Practical Guide to Portable Pupillometry , pp. 101 - 112
Publisher: Cambridge University Press
Print publication year: 2024

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  • Opioid Effect and Acute Pain
  • Merlin D. Larson, University of California, San Francisco
  • Book: A Practical Guide to Portable Pupillometry
  • Online publication: 14 November 2024
  • Chapter DOI: https://doi.org/10.1017/9781009436274.014
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  • Opioid Effect and Acute Pain
  • Merlin D. Larson, University of California, San Francisco
  • Book: A Practical Guide to Portable Pupillometry
  • Online publication: 14 November 2024
  • Chapter DOI: https://doi.org/10.1017/9781009436274.014
Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

  • Opioid Effect and Acute Pain
  • Merlin D. Larson, University of California, San Francisco
  • Book: A Practical Guide to Portable Pupillometry
  • Online publication: 14 November 2024
  • Chapter DOI: https://doi.org/10.1017/9781009436274.014
Available formats
×