Practical Psychopharmacology Book contents
- Practical Psychopharmacology
- Practical Psychopharmacology
- Copyright page
- Dedication
- Contents
- Foreword
- Preface
- Abbreviations
- Part I General Principles
- 1 Core Concepts of Good Psychopharmacology
- 2 Targets of Treatment: Categories versus Dimensions of Psychopathology
- 3 Interpreting and Using the Literature: Integrating Evidence-Based Trials with Real-World Practice
- 4 Placebo and Nocebo Effects
- 5 Tailoring the Fit: Moderators and Mediators of Treatment Outcome
- 6 Complex Regimens and Rationale-Based Combination Drug Therapies
- 7 Laboratory Values and Psychiatric Symptoms: What to Measure, What Not to Measure, and What to Do With The Results
- 8 Pharmacogenetics: When Relevant, When Not
- 9 Cross-tapering and the Logistics of Drug Discontinuation
- 10 Managing Major Adverse Drug Effects: When to Avoid, Switch, or Treat Through
- 11 Novel Drug Therapeutics: Nutraceuticals, Steroids, Probiotics, and Other Dietary Supplements
- 12 Human Diversity and Considerations in Special Populations
- Part II Targets of Pharmacotherapy
- References
- Index
2 - Targets of Treatment: Categories versus Dimensions of Psychopathology
from Part I - General Principles
Published online by Cambridge University Press: 19 October 2021
- Practical Psychopharmacology
- Practical Psychopharmacology
- Copyright page
- Dedication
- Contents
- Foreword
- Preface
- Abbreviations
- Part I General Principles
- 1 Core Concepts of Good Psychopharmacology
- 2 Targets of Treatment: Categories versus Dimensions of Psychopathology
- 3 Interpreting and Using the Literature: Integrating Evidence-Based Trials with Real-World Practice
- 4 Placebo and Nocebo Effects
- 5 Tailoring the Fit: Moderators and Mediators of Treatment Outcome
- 6 Complex Regimens and Rationale-Based Combination Drug Therapies
- 7 Laboratory Values and Psychiatric Symptoms: What to Measure, What Not to Measure, and What to Do With The Results
- 8 Pharmacogenetics: When Relevant, When Not
- 9 Cross-tapering and the Logistics of Drug Discontinuation
- 10 Managing Major Adverse Drug Effects: When to Avoid, Switch, or Treat Through
- 11 Novel Drug Therapeutics: Nutraceuticals, Steroids, Probiotics, and Other Dietary Supplements
- 12 Human Diversity and Considerations in Special Populations
- Part II Targets of Pharmacotherapy
- References
- Index
Summary
Diagnostic systems such as the DSM have long struggled over whether to organize psychiatric disorders as black-and-white categories defined by operational criteria (where “casehood” is unambiguously either present or absent) versus dimensions of psychopathology (where certain clinical elements are present but insufficient in number or duration to meet minimum criteria that define a particular clinical condition). Clinicians, meanwhile, often tend to identify and treat prominent symptoms, with varying degrees of awareness and concern about their broader context for defining the presence or absence of a distinct syndrome. In this chapter we will examine when pharmacological treatment targets can or should be thought of as unambiguous disease categories as opposed to dimensions of psychopathology that may not always be so clear-cut.
Diagnoses are clusters of signs and symptoms that should form a coherent constellation based on their inter-relationships.
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- Practical PsychopharmacologyTranslating Findings From Evidence-Based Trials into Real-World Clinical Practice, pp. 25 - 46Publisher: Cambridge University PressPrint publication year: 2021