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12 - Cerebrovascular Disease

from SECTION III - SPECIFIC NEUROLOGICAL CONDITIONS

Published online by Cambridge University Press:  06 August 2009

Michael R. Frankel
Affiliation:
Department of Neurology Grady Memorial Hospital Atlanta, Georgia
Marc Chimowitz
Affiliation:
Department of Neurology Grady Memorial Hospital Atlanta, Georgia
Sam Josvai
Affiliation:
Kalamazoo Center for Medical Studies/MSU Emergency Medicine Residency Program Kalamazoo, Michigan
Rashmi U. Kothari
Affiliation:
Kalamazoo Center for Medical Studies/MSU Emergency Medicine Residency Program Kalamazoo, Michigan
Sid M. Shah
Affiliation:
M.D. Ingham Regional Medical Center Sparrow Hospital/MSU, Emergency Medicine Residency Program Lansing, Michigan
Sid M. Shah
Affiliation:
Michigan State University
Kevin M. Kelly
Affiliation:
Drexel University, Philadelphia
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Summary

Cerebrovascular disease encountered in the emergency department (ED) includes transient ischemic attacks (TIAs) and infarcts (strokes). The purpose of the initial evaluation is to determine whether there is evidence of a stroke, what part of the brain is affected, and whether the patient is a candidate for urgent intervention such as thrombolytic therapy. A chemistry profile, complete blood count (CBC) with platelets, and coagulation profile are essential after completion of brief examination. Attention to adequate airway protection, oxygenation, and circulatory function is essential for management of patients with acute stroke. The use of anticoagulants (heparin or low molecular heparins) remains the most controversial subject in the management of acute stroke. Patients with acute or hemorrhagic strokes need to be admitted to the hospital for further evaluation and management. A neurosurgeon should participate in the care of most patients with intracerebral hemorrhages (ICH) and all patients with subarachnoid hemorrhages (SAH).
Type
Chapter
Information
Principles and Practice of Emergency Neurology
Handbook for Emergency Physicians
, pp. 131 - 145
Publisher: Cambridge University Press
Print publication year: 2003

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References

A special Writing Group of the Stroke Council, American Heart Association Guidelines for Thrombolytic Therapy for acute stroke. A supplement to the guidelines for the management of patients with acute ischemic stroke. 1996; 94: 1167–74
Albers, G W, Bates, V E, Clark, W M, Bell, R, Verro, Hamilton S A. Intravenous tissue-type plasminogen activator for treatment of acute stroke: the Standard Treatment with Altepase to Reverse Stroke (STARS) study. JAMA. 2000; 283: 1145–50Google Scholar
Bath, P M W, Lindenstrom, E, Boysen, G, et al. Tinzaparin in acute ischaemic stroke (TAIST): a randomized aspirin-controlled trial. Lancet. 2001; 358: 702–10Google Scholar
Berge, E, Abdelnoor, M, Nakstad, P H, Sandset, P M. Low molecular-weight heparin versus aspirin in patients with acute ischaemic stroke and atrial fibrillation: a double-blind randomised study. HAEST Study Group Heparin in Acute Embolic Stroke Trial. Lancet. 2000; 355: 1205–10Google Scholar
Broderick, J P, et al. Guidelines for the management of spontaneous intracerebral hemorrhage: a statement for healthcare professionals from a special writing group of the Stroke Council, American Heart Association. Stroke. 1999; 30: 905–15Google Scholar
CAST (Chinese Acute Stroke Trial) Collaboration Group. CAST: randomized placebo-controlled trial of early aspirin use in 20,000 patients with acute ischaemic stroke. Lancet. 1997; 349: 1641–9
Chen, Z M, Sandercock, P, Pan, H C, et al. Indications for early aspirin use in acute ischemic stroke: a combined analysis of 40,000 randomized patients from the Chinese acute stroke trial and the international stroke trial. On behalf of the CAST and IST collaborative groups. Stroke. 2000; 31: 1240–49Google Scholar
Ciuffetti, G, Aisa, G, Mercuri, M, et al. Effects of ticlopidine on the neurologic outcome and the hemorheologic pattern in the postacute phase of ischemic stroke: a pilot study. Angiology. 1990; 41: 505–11Google Scholar
Clark, W M, Wissman, S, Albers, G W, Jhamandas, J H, Madden, K P, Hamilton, S. Recombinant tissue-type plasminogen activator (Altepase) for ischemic stroke 3 to 5 hours after symptom onset. The ATLANTIS study: a randomized controlled trial. Altepase Thrombolysis for Acute Noninterventional Therapy in Ischemic Stroke. JAMA. 1999; 282: 1504–9Google Scholar
Counsell C, Sandercock P. Low-molecular-weight heparins or heparinoids versus standard unfractionated heparin for acute ischemic stroke. In: The Cochrane Library, Issue 1. Oxford, UK; 2000
Diener, H C, Ringelstein, E B, Kummer, R, et al. Treatment of acute ischemic stroke with the low-molecular-weight heparin certoparin. Results of the TOPAS Trial. Stroke. 2001; 32: 22–9Google Scholar
EAFT Study Group. Secondary prevention in non-rheumatic atrial fibrillation after transient ischaemic attack or minor stroke. Lancet. 1993; 342: 1255–62
European Stroke Council, European Neurological Society and European Federation of Neurological Societies. European Stroke Initiative recommendations for stroke management. Cerebrovasc Dis. 2000; 10: 335–51
Gubitz G, Counsell C, Sandercock P, et al. Anticoagulants for acute ischemic stroke (Cochrane Review). In: The Cochrane Library, Issue 1. Oxford, UK; 2000
Gubitz G, Sandercock P, Counsell C. Antiplatelet therapy for acute ischemic stroke. In: The Cochrane Library, Issue 1. Oxford, UK; 2000
International Stroke Trial Collaborative Group. The International Stroke Trial (IST): a randomized trial of aspirin, subcutaneous heparin, both, or neither among 19,435 patients with acute ischaemic stroke. Lancet. 1997; 349: 1569–81
Kay, R, Sing Wong, K, Yu, Y L, et al. Low-molecular-weight heparin for the treatment of acute ischemic stroke. N Engl J Med. 1995; 333: 1588–93Google Scholar
Lewandowski, C, Barsan, W. Treatment of acute ischemic stroke. Ann Emerg Med. 2001; 37: 202–16Google Scholar
McCarthy, S T, Turner, J. Low-dose subcutaneous heparin in the prevention of deep-vein thrombosis and pulmonary emboli following acute stroke. Age Ageing. 1986; 15: 84–8Google Scholar
Mayberg, M R, et al. Guidelines for the management of aneurismal subarachnoid hemorrhage. A statement for healthcare professional from a special writing group of the stroke council, American Heart Association, Circulation. 1994; 90: 2592–605Google Scholar
Multicentre Acute Stroke Trial – Italy (MAST-I) Group. Randomised controlled trial of streptokinase, aspirin, and combination of both in treatment of acute ischaemic stroke. Lancet. 1995; 346: 1509–14
Publications Committee for the Trial of ORG 10172 in Acute Stroke Treatment (TOAST) Investigators. Low molecular weight heparinoid, ORG 10172 (Dsanaparoid), and outcome after acute ischemic stroke. JAMA. 1998; 279: 1265–72
The Abciximab in Ischemic Stroke Investigators. Abciximab in acute ischemic stroke: a randomized, double-blind, placebo-controlled, dose-escalation study. Stroke. 2000; 31: 601–9
The NINDS rt-PA Stroke Study Group. Tissue plasminogen activator for acute ischemic stroke. N Engl J Med. 1995; 333:1581–7

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  • Cerebrovascular Disease
    • By Michael R. Frankel, Department of Neurology Grady Memorial Hospital Atlanta, Georgia, Marc Chimowitz, Department of Neurology Grady Memorial Hospital Atlanta, Georgia, Sam Josvai, Kalamazoo Center for Medical Studies/MSU Emergency Medicine Residency Program Kalamazoo, Michigan, Rashmi U. Kothari, Kalamazoo Center for Medical Studies/MSU Emergency Medicine Residency Program Kalamazoo, Michigan, Sid M. Shah, M.D. Ingham Regional Medical Center Sparrow Hospital/MSU, Emergency Medicine Residency Program Lansing, Michigan
  • Edited by Sid M. Shah, Michigan State University, Kevin M. Kelly, Drexel University, Philadelphia
  • Book: Principles and Practice of Emergency Neurology
  • Online publication: 06 August 2009
  • Chapter DOI: https://doi.org/10.1017/CBO9780511547256.013
Available formats
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Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

  • Cerebrovascular Disease
    • By Michael R. Frankel, Department of Neurology Grady Memorial Hospital Atlanta, Georgia, Marc Chimowitz, Department of Neurology Grady Memorial Hospital Atlanta, Georgia, Sam Josvai, Kalamazoo Center for Medical Studies/MSU Emergency Medicine Residency Program Kalamazoo, Michigan, Rashmi U. Kothari, Kalamazoo Center for Medical Studies/MSU Emergency Medicine Residency Program Kalamazoo, Michigan, Sid M. Shah, M.D. Ingham Regional Medical Center Sparrow Hospital/MSU, Emergency Medicine Residency Program Lansing, Michigan
  • Edited by Sid M. Shah, Michigan State University, Kevin M. Kelly, Drexel University, Philadelphia
  • Book: Principles and Practice of Emergency Neurology
  • Online publication: 06 August 2009
  • Chapter DOI: https://doi.org/10.1017/CBO9780511547256.013
Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

  • Cerebrovascular Disease
    • By Michael R. Frankel, Department of Neurology Grady Memorial Hospital Atlanta, Georgia, Marc Chimowitz, Department of Neurology Grady Memorial Hospital Atlanta, Georgia, Sam Josvai, Kalamazoo Center for Medical Studies/MSU Emergency Medicine Residency Program Kalamazoo, Michigan, Rashmi U. Kothari, Kalamazoo Center for Medical Studies/MSU Emergency Medicine Residency Program Kalamazoo, Michigan, Sid M. Shah, M.D. Ingham Regional Medical Center Sparrow Hospital/MSU, Emergency Medicine Residency Program Lansing, Michigan
  • Edited by Sid M. Shah, Michigan State University, Kevin M. Kelly, Drexel University, Philadelphia
  • Book: Principles and Practice of Emergency Neurology
  • Online publication: 06 August 2009
  • Chapter DOI: https://doi.org/10.1017/CBO9780511547256.013
Available formats
×