Skip to main content Accessibility help
×
Hostname: page-component-cd9895bd7-jn8rn Total loading time: 0 Render date: 2024-12-27T06:32:42.005Z Has data issue: false hasContentIssue false

Chapter 26 - Kidney Disease

from Section III - Care of the Elderly by Organ System

Published online by Cambridge University Press:  30 June 2022

Jan Busby-Whitehead
Affiliation:
University of North Carolina, Chapel Hill
Samuel C. Durso
Affiliation:
The Johns Hopkins University, Maryland
Christine Arenson
Affiliation:
Thomas Jefferson University, Philadelphia
Rebecca Elon
Affiliation:
The Johns Hopkins University School of Medicine
Mary H. Palmer
Affiliation:
University of North Carolina, Chapel Hill
William Reichel
Affiliation:
Georgetown University Medical Center
Get access

Summary

Kidney disease is common in older age and associated with adverse health outcomes. Guidelines recommend estimating GFR (eGFR) using a standardized estimating equation that includes age, race, gender, and serum creatinine. Management for chronic kidney disease (CKD) includes identification and management of underlying causes to slow the progression, recognition, and treatment of CKD-related complications, and preparation for renal replacement therapy prior to end-stage renal disease. Despite the high burden of CKD in older adults, the evidence underlying existing guidelines comes primarily from young and middle-aged adults and often does not take into account multimorbidity, geriatric conditions, and heterogeneity in life expectancy and health goals at older age. A person-centered approach to CKD that includes geriatric assessment, engages and supports family caregivers, and incorporates palliative care principles across the spectrum of kidney disease is appropriate for older adults.

Type
Chapter
Information
Reichel's Care of the Elderly
Clinical Aspects of Aging
, pp. 324 - 334
Publisher: Cambridge University Press
Print publication year: 2022

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Kidney Disease: Improving Global Outcomes (KDIGO) CKD Work Group. KDIGO 2012 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease. Kidney Int Suppl. 2013; 3(1):1150.Google Scholar
Bowling, CB, Muntner, P. Epidemiology of chronic kidney disease among older adults: A focus on the oldest old. J Gerontol A Biol Sci Med Sci. 2012; 67(12):13791386.Google Scholar
Coca, SG. Acute kidney injury in elderly persons. Am J Kidney Dis. 2010; 56(1):122131.Google Scholar
Bowling, CB, Booth, JN 3rd, Gutierrez, OM, Tamura, MK, Huang, L, Kilgore, M, Judd, S, Warnock, DG, McClellan, WM, Allman, RM, Muntner, P. Nondisease-specific problems and all-cause mortality among older adults with CKD: The REGARDS Study. Clin J Am Soc Nephrol. 2014; 9(10):17371745.Google Scholar
Muntner, P, Bowling, CB, Gao, L, Rizk, D, Judd, S, Tanner, RsM, McClellan, W, Warnock, DG. Age-specific association of reduced estimated glomerular filtration rate and albuminuria with all-cause mortality. Clin J Am Soc Nephrol. 2011; 6(9):22002207.Google Scholar
Centers for Disease Control and Prevention. Chronic Kidney Disease in the United States, 2019. Atlanta, GA: US Department of Health and Human Services, Centers for Disease Control and Prevention, 2019.Google Scholar
Bowling, CB, Sharma, P, Fox, CS, O’Hare, AM, Muntner, P. Prevalence of reduced estimated glomerular filtration rate among the oldest old from 1988–1994 through 2005–2010. JAMA. 2013; 310(12):12841286.Google Scholar
Bowling, CB, Sharma, P, Muntner, P. Prevalence, trends and functional impairment associated with reduced estimated glomerular filtration rate and albuminuria among the oldest-old U.S. adults. Am J Med Sci. 2014; 348(2):115120.Google Scholar
United States Renal Data System. 2019 Annual Data Report: Epidemiology of kidney disease in the United States. Bethesda, MD: National Institutes of Health, 2019.Google Scholar
Kurella, M, Covinsky, KE, Collins, AJ, Chertow, GM. Octogenarians and nonagenarians starting dialysis in the United States. Ann Intern Med. 2007; 146(3):177183.Google Scholar
O’Hare, AM, Batten, A, Burrows, NR, et al. Trajectories of kidney function decline in the 2 years before initiation of long-term dialysis. Am J Kidney Dis. 2012; 59(4):513522.Google Scholar
Moore, PK, Hsu, RK, Liu, KD. Management of acute kidney injury: Core curriculum 2018. Am J Kidney Dis. 2018; 72(1):136148.Google Scholar
Mesropian, PD, Othersen, J, Mason, D, Wang, J, Asif, A, Mathew, RO. Community-acquired acute kidney injury: A challenge and opportunity for primary care in kidney health. Nephrology (Carlton). 2016; 21(9):729735.Google Scholar
Anderson, S, Eldadah, B, Halter, JB, et al. Acute kidney injury in older adults. J Am Soc Nephrol. 2011; 22(1):2838.Google Scholar
Tangri, N, Stevens, LA, Griffith, J, Tighiouart, H, Djurdjev, O, Naimark, D, Levin, A, Levey, A. A predictive model for progression of chronic kidney disease to kidney failure. JAMA. 2011; 305(15):15531559.Google Scholar
Anderson, S, Halter, JB, Hazzard, WR, et al. Prediction, progression, and outcomes of chronic kidney disease in older adults. J Am Soc Nephrol. 2009; 20(6):11991209.CrossRefGoogle ScholarPubMed
Levey, AS, Stevens, LA, Schmid, CH, et al., for the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI). A new equation to estimate glomerular filtration rate. Ann Intern Med. 2009; 150(9):604612.Google Scholar
Glassock, R, Delanaye, P, El Nahas, M. An age-calibrated classification of chronic kidney disease. JAMA. 2015; 314(6):559560.CrossRefGoogle ScholarPubMed
Vandenberg, A, Echt, K, Johnson, TM 2nd, Bowling, CB. Patient discourse on chronic kidney disease monitoring and practical strategies for improving physician-patient communication: A qualitative study. BMC Nephrol. 2018; 19:183.Google Scholar
Sprint Research Group, Wright, JT Jr., Williamson, JD, Snyder, JK, et al. A randomized trial of intensive versus standard blood-pressure control. N Engl J Med. 2015; 373(22):21032116.Google Scholar
Whelton, PK, Carey, RM, Aronow, WS, et al. 2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA guideline for the prevention, detection, evaluation, and management of high blood pressure in adults: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. J Am Coll Cardiol. 2018 (May 15); 71(19):e127e248.Google Scholar
Bowling, CB, Vandenberg, A, Phillips, LS, McClellan, W, Johnson, TM 2nd, Echt, K. Older patients’ perspectives on managing complexity in CKD self-management. Clin J Am Soc Nephrol. 2017; 12(4):635643.Google Scholar
Fishbane, S, Spinowitz, B. Update on anemia in ESRD and earlier stages of CKD: Core curriculum 2018. Am J Kidney Dis. 2018; 71(3):423435.Google Scholar
Kidney Disease: Improving Global Outcomes CKD-MBD Work Group. KDIGO 2017 clinical practice guideline update for the diagnosis, evaluation, prevention, and treatment of chronic kidney disease – mineral and bone disorder (CKD-MBD). Kidney Int Suppl (2011). 2017; 7(1):159.Google Scholar
Wong, SPY, Boyapati, S, Engelberg, RA, Thorsteinsdottir, B, Taylor, JS, O’Hare, AM. Experiences of US nephrologists in the delivery of conservative care to patients with advanced kidney disease: A national qualitative study. Am J Kidney Dis. 2020; 75(2):167176.CrossRefGoogle ScholarPubMed
Bowling, CB, O’Hare, AM. Managing older adults with CKD: Individualized versus disease-based approaches. Am J Kidney Dis. 2012; 59(2):293302.CrossRefGoogle ScholarPubMed
O’Hare, AM, Rodriguez, RA, Bowling, CB. Caring for patients with kidney disease: Shifting the paradigm from evidence-based medicine to patient-centered care. Nephrol Dial Transplant. 2016; 31(3):368375.Google Scholar
Bowling, CB, Plantinga, L, Phillips, LS, McClellan, W, Echt, K, Chumbler, N, McGwin, G, Vandenberg, A, Allman, RM, Johnson, TM 2nd. Association of multimorbidity with mortality and healthcare utilization in chronic kidney disease. J Am Geriatr Soc. 2017; 65(4):704711.Google Scholar
Hall, RK, Zhou, H, Reynolds, K, Harrison, TN, Bowling, CB. A novel approach to developing a discordance index for older adults with chronic kidney disease. J Gerontol A Biol Sci Med Sci. 2020; 75(3):522528.Google Scholar
Plantinga, LC, Patzer, RE, Franch, HA, Bowling, CB. Serious fall injuries before and after initiation of hemodialysis among older ESRD patients in the United States: A retrospective cohort study. Am J Kidney Dis. 2017; 70(1):7683.Google Scholar
Bowling, CB, Batten, A, O’Hare, AM. Distribution of survival times in a real-world cohort of older adults with chronic kidney disease: The median may not be the message. J Am Geriatr Soc. 2015; 63(5):10331035.Google Scholar
Morton, RL, Sellars, M. From patient-centered to person-centered care for kidney diseases. Clin J Am Soc Nephrol. 2019; 14(4):623625.Google Scholar
Valentijn, PP, Pereira, FA, Ruospo, M, Palmer, SCs, Hegbrant, J, Sterner, VW, Vrijhoef, HJM, Ruwaard, D, Strippoli, GFM. Person-centered integrated care for chronic kidney disease: A systematic review and meta-analysis of randomized controlled trials. Clin J Am Soc Nephrol. 2018; 13(3):375386.Google Scholar
Hall, RK, Haines, C, Gorbatkin, SM, Schlanger, L, Shaban, H, Schell, JO, Gurley, SB, Colon-Emeric, CS, Bowling, CB. Incorporating geriatric assessment into a nephrology clinic: Preliminary data from two models of care. J Am Geriatr Soc. 2016; 64(10):21542158.CrossRefGoogle ScholarPubMed
Bowling, CB, Plantinga, L, Hall, RK, Mirk, A, Zhang, R, Kutner, N. Association of nondisease-specific problems with mortality, long-term care, and functional impairment among older adults who require skilled nursing care after dialysis initiation. Clin J Am Soc Nephrol. 2016; 11(12):22182224.Google Scholar
Bowling, CB, Muntner, P, Sawyer, P, Sanders, PW, Kutner, N, Kennedy, R, Allman, RM. Community mobility among older adults with reduced kidney function: A study of life-space. Am J Kidney Dis. 2014; 63(3):429436.Google Scholar
Hoang, VL, Green, T, Bonner, A. Informal caregivers’ experiences of caring for people receiving dialysis: A mixed-methods systematic review. J Ren Care. 2018; 44(2):8295.Google Scholar
DePasquale, N, Cabacungan, A, Ephraim, PL, Lewis-Boyer, L, Powe, NR, Boulware, LE. Perspectives of African-American family members about kidney failure treatment. Nephrol Nurs J. 2020; 47(1):5365.Google Scholar
Nygardh, A, Wikby, K, Malm, D, Ahlstrom, G. Empowerment in outpatient care for patients with chronic kidney disease – From the family member’s perspective. BMC Nurs. 2011; 10:21.CrossRefGoogle ScholarPubMed
Flythe, JE, Hilbert, J, Kshirsagar, AV, Gilet, CA. Psychosocial factors and 30-day hospital readmission among individuals receiving maintenance dialysis: A prospective study. Am J Nephrol. 2017; 45(5):400408.Google Scholar
Sugisawa, H, Shinoda, T, Shimizu, Y, Kumagai, T, Sugisaki, H, Sugihara, Y. Caregiving for older adults requiring hemodialysis: A comparison study. Ther Apher Dial. 2020; 24(4):423430. doi: 10.1111/1744-9987.13453.Google Scholar
Kurella Tamura, M, Cohen, LM. Should there be an expanded role for palliative care in end-stage renal disease? Curr Opin Nephrol Hypertens. 2010; 19(6):556560.Google Scholar
Renal Physicians Association. Shared Decision-Making in the Appropriate Initiation of and Withdrawal from Dialysis. Clinical practice guideline, 2nd edition. Rockville, MD: The Association, 2010.Google Scholar

Save book to Kindle

To save this book to your Kindle, first ensure no-reply@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×