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Case 22 - A 40-Year-Old G0 Woman with Endometrial Intraepithelial Neoplasia Desiring Hysterectomy

Published online by Cambridge University Press:  19 November 2021

Todd R. Jenkins
Affiliation:
University of Alabama, Birmingham
Lisa Keder
Affiliation:
Ohio State University School of Medicine, Columbus
Abimola Famuyide
Affiliation:
Mayo Clinic, Rochester
Kimberly S. Gecsi
Affiliation:
Medical College of Wisconsin
David Chelmow
Affiliation:
Virginia Commonwealth University School of Medicine
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Summary

A 40-year-old nulligravid woman last menstrual period 15 weeks ago presents with irregular menstrual bleeding. Upon questioning, she has had irregular cycles for the last 20 years. She has never taken any hormonal medication to regulate her bleeding. She has never been pregnant despite not using contraception since age 21. You perform an endometrial biopsy and the pathologic diagnosis is endometrial intraepithelial neoplasia (EIN). She does not desire future fertility. Her past medical history is significant for hypertension and morbid obesity. She was recently diagnosed with diabetes and has adjusted her diet to try and control her blood sugar. She requests to have a hysterectomy for treatment of her irregular menses. She denies any significant family history of breast, ovarian, or colon cancer. She has no past surgical history. She is currently taking hydrochlorothiazide 25 mg PO daily and has no known drug allergies.

Type
Chapter
Information
Surgical Gynecology
A Case-Based Approach
, pp. 61 - 63
Publisher: Cambridge University Press
Print publication year: 2021

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References

Javadian, P, Nezhat, F. Endometrial carcinoma and its precursors. Adv Exp Med Biol 2020; 1242: 5972.CrossRefGoogle ScholarPubMed
Parkash, V, Fadare, O, Tornos, C, McCluggage, WG. Committee Opinion No. 631: Endometrial intraepithelial neoplasia. Obstet Gynecol 2015; 126(4): 897.Google Scholar
Trimble, CL, Method, M, Leitao, M, et al. Management of endometrial precancers. Obstet Gynecol 2012; 120(5): 1160–75.CrossRefGoogle ScholarPubMed
Gentry-Maharaj, A, Karpinskyj, C. Current and future approaches to screening for endometrial cancer. Best Pract Res Clin Obstet Gynaecol 2020; 65: 7997.CrossRefGoogle ScholarPubMed
Owings, RA, Quick, CM. Endometrial intraepithelial neoplasia. Arch Pathol Lab Med 2014; 138(4): 484–91.CrossRefGoogle ScholarPubMed
Sobczuk, K, Sobczuk, A. New classification system of endometrial hyperplasia WHO 2014 and its clinical implications. Menopause Rev 2017; 16(3): 107–11.Google ScholarPubMed
Perkins, RB, Guido, RS, Castle, PE, et al. 2019 ASCCP Risk-Based Management Consensus Guidelines for Abnormal Cervical Cancer Screening Tests and Cancer Precursors. J Low Genit Tract Dis 2020; 24(2): 102–31.Google ScholarPubMed
Ceci, O, Bettocchi, S, Pellegrino, A, et al. Comparison of hysteroscopic and hysterectomy findings for assessing the diagnostic accuracy of office hysteroscopy. Fertil Steril 2002; 78(3): 628–31.CrossRefGoogle ScholarPubMed
Practice Bulletin No. 149: Endometrial cancer. Obstet Gynecol 2015; 125(4): 1006–26.Google Scholar
Rungruang, B, Olawaiye, A. Comprehensive surgical staging for endometrial cancer. Rev Obstet Gynecol 2012; 5(1): 2834.Google ScholarPubMed

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