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Obstetric complications and neurological soft signs in male patients with schizophrenia

Published online by Cambridge University Press:  24 June 2014

Giuseppe Bersani ,
Roberta Clemente ,
Simona Gherardelli ,
Francesco Saverio Bersani  and
Giorgiana Manuali
Giuseppe Bersani*
Affiliation:
Department of Medical – Surgical Sciences and Biotechnologies, Sapienza University of Rome, Rome, Italy
Roberta Clemente
Affiliation:
Department of Medical – Surgical Sciences and Biotechnologies, Sapienza University of Rome, Rome, Italy
Simona Gherardelli
Affiliation:
Department of Medical – Surgical Sciences and Biotechnologies, Sapienza University of Rome, Rome, Italy
Francesco Saverio Bersani
Affiliation:
Department of Medical – Surgical Sciences and Biotechnologies, Sapienza University of Rome, Rome, Italy
Giorgiana Manuali
Affiliation:
Department of Medical – Surgical Sciences and Biotechnologies, Sapienza University of Rome, Rome, Italy
*
Prof. Giuseppe Bersani, Department of Medical – Surgical Sciences and Biotechnologies, Sapienza University of Rome, via di Torre Argentina 21, 00186 Rome, Italy. Tel: +39 06 4454765; Fax: +39 06 6875237; E-mail: giuseppe.bersani@uniroma1.it
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Extract

Bersani G, Clemente R, Gherardelli S, Bersani FS, Manuali G. Obstetric complications and neurological soft signs in male patients with schizophrenia.

Objective: The study investigated the relationship between neurological soft signs (NSS) and obstetric complications (OCs) in patients with schizophrenia.

Methods: Sixty-three male patients with schizophrenia were divided into two subgroups, based on the OCs presence or absence, which were compared in relation to NSS prevalence. After that, a Person's correlation test was performed to explore the correlation between NSS and OCs severity.

Results: The subgroup with OCs showed more NSS, but there were not significant correlations between NSS and OCs severity.

Conclusions: It seems that any OC, without distinction in typology and severity, could unspecifically impair the neurodevelopment and inducing NSS expression. Our findings confirm the hypothesis that neurodevelopment alterations, such as those probably induced by OCs, can contribute to a premorbid brain dysfunctional state expressed by NSS.

Keywords

neurodevelopmentneurological soft signsobstetric complicationsschizophrenia
Type
Research Article
Information
Acta Neuropsychiatrica , Volume 24 , Issue 6 , December 2012 , pp. 344 - 348
Copyright
Copyright © Cambridge University Press 2011

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