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Complex Symptomatology Simulated By Unstructured Neural Nets

Published online by Cambridge University Press:  18 September 2015

R.A. Cyrulnik ,
P.A. Anninos  and
R. Marsh
R.A. Cyrulnik
Affiliation:
Department of Anatomy and Biomathematics School of Medicine and The Mental Retardation Program, Neuropsychiatric Institute, University of California, Los Angeles, California 90024
P.A. Anninos*
Affiliation:
Department of Anatomy and Biomathematics School of Medicine and The Mental Retardation Program, Neuropsychiatric Institute, University of California, Los Angeles, California 90024
R. Marsh
Affiliation:
Department of Anatomy and Biomathematics School of Medicine and The Mental Retardation Program, Neuropsychiatric Institute, University of California, Los Angeles, California 90024
*
Dept. of Physics, Dawson College, 350 Selby St., West-mount, P.Q, Canada
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Summary

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A neural net model with random interconnections is shown capable of exhibiting the features of Parkinson’s disease, including cogwheel rigidity, resting tremor, and dysdiadochokinesis. These properties are simulated uniquely for extrapyramidal disease, with spasticity and hypereflexia predicted for other upper motoneuron lesions.

Type
Research Article
Information
Canadian Journal of Neurological Sciences , Volume 1 , Issue 1 , February 1974 , pp. 17 - 22
Copyright
Copyright © Canadian Neurological Sciences Federation 1974

References

1.Andersen, P. (1966). “Rhythmic10c/sec activity in the Thalamus,” in: The Thalamus, New York: Columbia University Press (Purpura, ed.).Google Scholar
2.Anninos, P.A.Beek, B.Csermely, T.J.Harth, E.M. and Pertile, G. (1970). Dynamics of Neural structures. Journal of Theoretical Biology, 26, pp.121– 148.CrossRefGoogle ScholarPubMed
3.Anninos, P.A. (1969), “Dynamics and function of neural structures,” Ph.D. Thesis, University Microfilms, Ann Arbor, Michigan, 1970.Google Scholar
4.Anninos, P.A. and Harth, E.M. (1971). Hysteresis Effects in Artificial Neural Nets, 24th ACEMB, 13, pp. 121.Google Scholar
5.Anninos, P.A. (1972a). Mathematical model of memory trace and forgetfulness. Kybernetik, 10, pp. 165–167.CrossRefGoogle ScholarPubMed
6.Anninos, P.A. (1972b). Cyclic modes in artificial neural nets. Kybernetik, 11, pp. 5–14.CrossRefGoogle ScholarPubMed
7.Hassler, R. (1937). Zur pathologie der paralysis agitans und des postencephlitische parkinsonismus. J. Psychol., 48, 367.Google Scholar
8.Hoffman, P. (1951). Die Aufklarung der Wickung de Jendrassikschen Handgriffsdurch de Arbeiten von Sommer und Kuffler. Dtsch. Z. Nervenheilk, 166, pp. 60–64.CrossRefGoogle Scholar
9.Jasper, H.H. and Bertrand, G. (1966). “Thalamic Units involved in somatic sensation and voluntary and involuntary movements,” in: The Thalamus, New York: Columbia University Press (Purpura, D., ed.), pp. 365–390.Google Scholar
10.Jung, R. and Hassler, R. (1960). The extrapyramidal motor system, in: Handbook of Physiology, pp.863–927.Google Scholar
11.Liddell, E.G.T. and Sherrington, C.S. (1925). Further observations on myotatic reflexes. Proc. Roy. Soc. B., 97, pp.267–283.Google Scholar
12.Merritt, H.H. (1967). “A Textbook of Neurology,” Philadelphia, Lea and Febiger, pp.473–482.Google Scholar
13.Mettler, F.A. (1942). Relations between pyramidal and extrapyramidal function. Res. Publ. Ass. Nerv. Ment. Dis., 21, pp. 150–227.Google Scholar
14.Patton, H.D. (1945). “Reflexregulation of movement and posture,” in: Neurophysiology, Philadelphia: W.B. Saunders (Ruch, T.C.Patton, H.D.Woodbury, J.W. and Towe, A.L. eds.), 184–195.Google Scholar
15.Pollock, L.G. and Davis, L.(1930). Muscle tone in parkinsonian states. Arch. Neurol, and Psychiat. (Chicago), 303–317.Google Scholar
16.Ruch, T.C. (1965). “The cerebral Cortex: Its Structure and Motor Function,” in Neurophysiology, Philadelphia: W.B. Saunders (Ruch, T.C.Patton, H.D.Woodbury, J.W. and Towe, A.L. eds.), 273.Google Scholar
17.Sommer, J. “Periphere bahnung von muskeleigenreflexen als wesen des jendrassikschen phanomena.” Dtsch.Z.Nervenheilk, 150, pp. 249–269.CrossRefGoogle Scholar
18.Tower, S.S. (1949). Chapter 6 in: The precentral motor cortex, 2nd ed. (Bucy, P. C , ed.), Univ. of III. Press, Urbana, 14, 615.Google Scholar
19.Ward, A.J. (1968). “The function of the basal ganglia,” in: Handbook of clinical Neurology (Vinken, P.J. and Bruyn, G.W. eds.), North-Holland Publishing Co., Amsterdam.Google Scholar